Brendan McDermid/Reuters
Tosi has been with Blackstone since 2008, according to the report. In that time, the firm more than doubled its assets under management to $333 million.
At Airbnb, he would replace Andrew Swain, who left his role as CFO a year ago.
This is not the first Wall Street financial chief to ditch the industry for tech.
In March, Morgan Stanley's CFO, Ruth Porat, made headlines when she left that investment bank for Google.
And it's not just the CFOs, either.
In the past several years, all of these Wall Street bankers and dealmakers have jumped ship for tech:
Bankers are being drawn to Silicon Valley riches as investment banking becomes a less lucrative profession. Google's paying Porat as much as $70 million in salary and bonuses, filings show.
"Tosi has gone from 'Hard Times' to 'Field of Dreams,' if this were the movies," said Richard Stein, a partner at Wall Street search firm Options Group. It's "a good choice for him and Airbnb."
Business Insider has reached out to Blackstone for comment. Request for comment to Airbnb was not returned.