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Only human trials will help understand the efficacy of the new Rs 100 pill developed to prevent recurrence of cancer, said doctors on Wednesday. According to a report by NDTV, researchers at the Tata Memorial Centre (<keyword id="19942089" type="General" weightage="20" keywordseo="tmc" source="keywords">TMC</keyword>) in Mumbai claimed to have discovered a treatment to prevent relapse of cancer that would cost only Rs 100. The study on mice showed that the pill, named 'R+Cu', containing a pro-oxidant combination of resveratrol and copper, generated oxygen radicals in the stomach to curb cancer recurrence. The experimental mice study "is not a substitute for established treatments, which continue to result in cures in a substantial proportion of cancer patients," Dr <keyword id="20763261" type="General" weightage="20" keywordseo="shyam-aggarwal" source="keywords">Shyam Aggarwal</keyword>, Chairman, Department of Medical Oncology, at Sir <keyword id="20162656" type="General" weightage="20" keywordseo="ganga-ram-hospital" source="keywords">Ganga Ram Hospital</keyword> told IANS. In a post on X, Dr. <keyword id="20763262" type="General" weightage="20" keywordseo="rajeev-jayadevan" source="keywords">Rajeev Jayadevan</keyword>, Co-Chairman National IMA Covid Task Force called it "an exaggerated claim". While calling the research "interesting, praiseworthy", he said it cannot be seen as "cancer cure." Dr Shyam Aggarwal explained that the research shows the effect of cell-free chromatin (fragments of chromosomes released from cancer cells after chemotherapy) on normal tissues causing a cascade of inflammation leading to side effects such as mucositis, low blood counts, etc. "Use of a combination of copper and resveratrol (a commercially-available nutraceutical) has been shown to degrade circulating cell-free chromatin, leading to reduction of toxicity in some human studies. Other human studies are underway," he said. The study claims that the pill can halve the side effects caused by chemotherapy, while also reducing the odds of getting cancer by 30 per cent. The researchers "used a pro-oxidant combination of copper and resveratrol (found in peanuts, cocoa, grapes) known to damage DNA by generating oxygen radicals," Dr. Rajeev Jayadevan wrote in his post on X. "Whether this will translate into real world outcomes for people with cancer (beyond mice), what toxicities could occur from its pro-oxidant, DNA-damaging effect, is yet to be determined," he said. However, Dr. <keyword id="20763263" type="General" weightage="20" keywordseo="rahul-bhargava" source="keywords">Rahul Bhargava</keyword>, Principal Director &amp; Chief BMT, Fortis Memorial Research Institute, Gurugram, called it "a great breakthrough in the field of medical research. Indian researchers are creating history. If the drug works, it will be a great benefit for cancer patients." "The tablet is promising and shows potential to be effective, but human trials are yet to be completed, which could take about five years," he told IANS. The tablet is awaiting approval from the Food Safety and Standards Authority of India (FSSAI) and is expected to be available in the market by June-July. --IANS rvt/rad

Human trials may reveal efficacy of new Rs 100 cancer pill: Docs

<ul><li>With their sales being hit, the Indian business community which has so far been an active supporter of the Indian government, has been raising its voices.</li><li><keyword id="6359432" type="UNKNOWN" weightage="20" keywordseo="britannia">Britannia</keyword>’s MD Varun Berry said there is some serious issue in the economy.</li><li>He’s not alone, leaders from the auto industry have raised their concerns as the segment is witnessing its worst sales slowdown.</li></ul>Questions are being raised by top Indian businessmen about the economic health of the country. The latest one to cry foul is fast moving consumer goods company Britannia. In the <a href="https://www.dnaindia.com/business/report-consumers-thinking-twice-before-buying-a-rs-5-pack-britannia-2781047">latest earnings call</a> of Britannia, the company’s MD Varun Berry raised some serious concerns about the <keyword id="6356076" type="DEFINITION" weightage="20" keywordseo="indian-economy">Indian economy</keyword>. "We've grown only 6% and the market is growing slower than that. And that's a little bit of a worry, because even for a ₹5 product if the consumer is thinking twice before buying it, then there is some serious issue in the economy,” he said. This comes in even though Britannia holds one-third of market share in the Indian biscuit industry. With their sales hit, the Indian business community which has so far been an active supporter of the Indian government, has been raising its voices. India’s GDP has slumped to 6.8% in FY19, whereas <a href="https://www.businesstoday.in/current/economy-politics/india-economy-9-per-cent-gdp-growth-pm-modi-5-trillion-dollar-economy-target-ey/story/370433.html">analysts </a>say that for India to reach its dream of being a $5 trillion economy, the country’s GDP needs to grow steadily at 9%. The industry that has been worst hit has the auto industry which has seen a massive slowdown in sales has seen. Auto industry leaders like Pawan Munjal of HeroCorp, RC Bhargava of Maruti, Anand Mahindra of Mahindra &amp; Mahindra, have all been rallying for reduction of GST to boost growth in sales. Rahul Bajaj, the chairman of Indian conglomerate Bajaj Group. During his company’s Annual General Meeting, he spoke of the government’s role in the weak sales of the auto industry. “There is no demand and no private investment, so where will growth come from? It doesn’t fall from the heavens. The auto industry is going through a very difficult period. Cars, commercial vehicles and two-wheelers are going through a rough patch,” Bajaj added. Earlier, Adi Godrej, chairman of the Godrej group, too <a href="https://www.firstpost.com/business/industry-leaders-reaction-on-budget-2019-adi-godrej-says-budget-is-not-growth-oriented-stock-market-comes-down-considerably-6940161.html">said</a> that the Budget presented by Finance Minister Nirmala Sitharaman is not “growth-oriented”. <a href="https://www.ndtv.com/india-news/adi-godrej-rising-intolerance-hate-crimes-can-seriously-damage-growth-2068996">Godrej also touched upon a sensitive subject </a>saying that rising intolerance in the country is also affecting growth. However, there are also some who believe this is just a phase. HDFC Chairman <a href="https://www.businesstoday.in/current/economy-politics/indias-economic-slowdown-driven-by-lower-consumption-temporary-in-nature-says-hdfcs-deepak-parekh/story/370229.html">Deepak Parekh</a> in the recent annual general meeting of the bank said, “While there has been an across-the-board slowdown in consumption, given the inherent demand and low penetration levels, I believe this is temporary in nature.”

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Human trials may reveal efficacy of new Rs 100 cancer pill: Docs

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