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<ul class="summary-list"><li>Social media star <keyword id="12954417" type="UNKNOWN" weightage="60" keywordseo="adalia-rose-williams" source="Orion">Adalia Rose Williams</keyword> died on Wednesday. She was 15.</li><li>The YouTuber had a <keyword id="12948404" type="UNKNOWN" weightage="60" keywordseo="genetic-condition" source="Orion">genetic condition</keyword> called <keyword id="12948403" type="UNKNOWN" weightage="60" keywordseo="progeria" source="Orion">progeria</keyword> that is characterized by rapid aging.</li></ul><keyword id="12954416" type="UNKNOWN" weightage="60" keywordseo="michael-costello" source="Orion">Michael Costello</keyword>, a fashion designer featured on "Project Runway," paid tribute to social media star Adalia Rose Williams after her family announced that the 15-year-old had died. Costello <a href="https://www.instagram.com/p/CYrxI_0PFnk/" target="_blank" rel="noopener">wrote on Instagram</a> that his heart was "broken" at the <keyword id="11893589" type="UNKNOWN" weightage="100" keywordseo="news" source="Orion">news</keyword> Williams "was called home to God.""I am at a loss for words and cannot stop crying," he said. "Adalia has been so special to every single person that she met. She was an angel. Despite the cards she was dealt with, she had the most positive attitude and such big dreams of helping everyone around her."Williams died on Wednesday evening, according to posts on <a href="https://www.instagram.com/p/CYqNhVVsGpL/">her Instagram</a> and <a href="https://www.facebook.com/photo/?fbid=458523922396156&amp;set=a.277220670526483">Facebook</a> pages. Her mother Natalia Pallante also posted <a href="https://www.instagram.com/p/CYqNcZsMRCY/" target="_blank" rel="noopener">on the family's shared Instagram page</a> that Williams was "set free from this world" on January 12.Williams had 2.9 million subscribers on her YouTube channel, where she documented living with a genetic condition called progeria that is characterized by rapid aging. Children with the condition have an average life expectancy of 13 years, according to <a href="https://www.mayoclinic.org/diseases-conditions/progeria/symptoms-causes/syc-20356038">Mayo Clinic</a>.Costello added Williams had changed his life, and he would miss her dearly."I promise to cherish all the wonderful memories we've had together," he said.Costello posted four videos with his statement, showing Williams receiving and trying on dresses he had designed and made for her. One of the clips showed a video message from Williams thanking Costello for the dresses.Costello also shared Williams' family's statement about her death, along with <a href="https://www.gofundme.com/f/memorial-for-adalia-rose?utm_source=customer&amp;utm_medium=copy_link_all&amp;utm_campaign=m_pd+share-sheet" target="_blank" rel="noopener">a GoFundMe link</a> to raise money for Williams' funeral costs and medical expenses.

Designer Michael Costello pays tribute to social media star Adalia Rose Williams, who died at 15: 'She was an angel'

<ul class="summary-list"><li>Adalia Rose Williams, a YouTuber with a rare <keyword id="12948404" type="UNKNOWN" weightage="60" keywordseo="genetic-condition" source="Orion">genetic condition</keyword>, has died, her social accounts say.</li><li>Williams had <keyword id="12948403" type="UNKNOWN" weightage="60" keywordseo="progeria" source="Orion">progeria</keyword>, a condition that involves rapid aging.</li></ul>Adalia Rose Williams, a social-media star who documented her life with a rare genetic condition, has died at 15, according to posts on <a href="https://www.instagram.com/p/CYqNhVVsGpL/">her Instagram</a> and <a href="https://www.facebook.com/photo/?fbid=458523922396156&amp;set=a.277220670526483">Facebook</a> pages. She died Wednesday evening, the posts said. The Texas teenager had over 12 million Facebook followers and 2.9 million subscribers on <keyword id="11894124" type="UNKNOWN" weightage="60" keywordseo="youtube" source="Orion">YouTube</keyword>, where she posted health updates, makeup videos, comedy skits, and videos featuring her family members."She touched MILLIONS of people and left the biggest imprint in everyone that knew her," the post, which was published Wednesday evening, said. "She is no longer in pain and is now dancing away to all the music she loves."Williams was diagnosed with Hutchinson-Gilford progeria syndrome when she was about 3 months old, her mother, Natalia Pallante, told <a href="https://www.nzherald.co.nz/lifestyle/adalia-rose-11-suffers-from-a-rare-genetic-condition-that-accelerates-the-ageing-process/73EGXHZCPBEK7LF54SPZJCREXM/">The New Zealand Herald</a> in 2018.The condition, also known as progeria, has no known cure and causes children to age much faster than normal, with symptoms including hair loss and slow growth, according to <a href="https://www.mayoclinic.org/diseases-conditions/progeria/symptoms-causes/syc-20356038">Mayo Clinic</a>. The average life expectancy for a child with the condition is 13 years old, according to Mayo Clinic. About 400 children across the globe have the condition, according to <a href="https://www.progeriaresearch.org/progeria-101faq/">the Progeria Research Foundation</a>.Williams' earliest videos date to 2012 and feature her dancing. The YouTube star's most recent video, posted in November, shows her unboxing a silicone baby doll named Luka. Her channel has over 339 million views. An email address listed on Williams' Facebook page did immediately return to Insider's request for comment.

Adalia Rose Williams, a social-media star who documented her life with a rare genetic disorder, has died at 15

<ul class="summary-list"><li>There were many important scientific discoveries unrelated to COVID-19 this year.</li><li>Scientists have studied and developed new treatments for everything from depression to rare genetic disease.</li></ul><keyword id="11908717" type="UNKNOWN" weightage="60" keywordseo="2021" source="Orion">2021</keyword> was another big year for coronavirus <keyword id="12094404" type="UNKNOWN" weightage="60" keywordseo="research" source="Orion">research</keyword>, as vaccines were authorized and new treatments developed. But the scope of scientific discovery extended beyond the pandemic into other areas of <keyword id="11894571" type="UNKNOWN" weightage="100" keywordseo="health" source="Orion">health</keyword>.This year, we saw advancements in treating other illnesses big and small, from groundbreaking to wacky.Here are six of the most remarkable health discoveries of the year. <h2>Medical psychedelics</h2><div type="image" title="Psilodep psychedelic research at Imperial College London" height="2664" width="3552" msid="88523947" hostid="261"></div>Psychedelic drugs have shown promise for treating several mental health conditions in recent years. In 2021, two studies reinforced the success of mind-altering substances in combination with therapy.For people with post-traumatic stress disorder, the party drug MDMA may offer some relief. In a phase 3 clinical trial with results published in <a href="https://www.nature.com/articles/s41591-021-01336-3.pdf">Nature Medicine</a>, 67% of patients who received MDMA along with talk therapy saw such an improvement that they no longer qualified for the diagnosis two months after treatment.Separately, the <a href="https://ir.compasspathways.com/news-releases/news-release-details/compass-pathways-announces-positive-topline-results">largest randomized controlled trial of psilocybin</a>, the active ingredient in "magic" mushrooms, found that the hallucinogenic-assisted therapy significantly reduced symptoms of treatment-resistant depression.In an <a href="https://www.nejm.org/doi/full/10.1056/NEJMoa2032994">earlier study</a> of psilocybin as a treatment for depression (April vs. November), two sessions with the psychedelic worked "at least as well" as a daily dose of escitalopram, the antidepressant also known as Lexapro.<h2>A blood test that spots 50 types of cancer</h2><div type="image" title="Blood sample" height="3398" width="4530" msid="88523949" hostid="261"></div>A new technology could reveal early signs of more than 50 types of cancer based on a single blood draw.The <a href="https://www.galleri.com/hcp/the-galleri-test">Galleri test</a>, made by biotech giant Illumina, looks for DNA fragments in the blood that could signal the presence of cancer. Those fragments can also point to the location of a tumor with "high accuracy," giving patients a head start on diagnosis and treatment.In <a href="https://www.annalsofoncology.org/article/S0923-7534%2821%2902046-9/fulltext#%20">clinical trials</a> involving people who had already been diagnosed with cancer, the Galleri test identified 51.9% of cancers at any stage of development. However, the test could come in handy for catching cancers that are not diagnosed at regular screenings.Doctors <a href="https://www.businessinsider.com/cancer-detecting-blood-tests-are-set-to-hit-the-market-by-2022-2021-10">previously told Insider</a> that the Galleri test and similar diagnostics need to improve their success rates, but they could make a real difference for individual patients. Early diagnosis has been proven to improve cancer outcomes and may let patients avoid the physical toll of chemotherapy.The "liquid biopsy" is advertised to return results within 10 business days, and it's meant to be ordered by healthcare providers along with other screening tools. Although the FDA approval hasn't come through yet, you can get a Galleri test with a doctor's prescription for $949. <h2>The first treatment for progeria</h2><div type="image" title="sibling with progeria" height="2661" width="3548" msid="88523951" hostid="261"></div><a href="https://www.mayoclinic.org/diseases-conditions/progeria/symptoms-causes/syc-20356038">Progeria</a> is a genetic disease that causes features of premature aging in roughly 400 children worldwide. Until recently, there was no treatment to slow the progression of disease. It's typically fatal after an average of 13 years.<a href="https://www.zokinvy.com/">Zokinvy</a>, a new drug developed by Eiger Pharmaceuticals this year, can extend that lifespan by about 2.5 years. Zokivny is the first and only FDA-approved treatment for Hutchinson-Gilford progeria syndrome, and it works by preventing the buildup of detective proteins.Those faulty proteins, called progerin, typically cause cells to die and damage the heart and bones. Children with progeria usually die of heart failure or stroke, according to <a href="https://www.mayoclinic.org/diseases-conditions/progeria/symptoms-causes/syc-20356038">Mayo Clinic</a>.In clinical trials, Zokivny prolonged lifespans by an average of 2.5 yeaand either reduced or delayed the onset of symptoms associated with the disease. The earlier the <keyword id="12037532" type="UNKNOWN" weightage="60" keywordseo="medicine" source="Orion">medicine</keyword> was given, the greater the benefit.<h2>An implant to heal the ACL</h2><div type="image" title="ACL knee injury" height="3491" width="4655" msid="88523953" hostid="261"></div>The ACL, or the anterior cruciate ligament, is the most common source of knee injury, according to a 2016 report in the <a href="https://www.journals.elsevier.com/journal-of-clinical-orthopaedics-and-trauma">Journal of Clinical Orthopedics and Trauma</a>.The injury is as devastating as it is common. Repairing a torn ACL can involve multiple surgeries or even a full reconstruction, which requires removing a healthy tendon for grafting and means a lengthier recovery.A new knee implant recently approved by the FDA can "basically stimulate the ACL to heal itself," Martha Murray, MD, orthopedic surgeon-in-chief at Boston Children's Hospital and creator of the BEAR implant, said in a <a href="https://miachortho.com/about-us/news-and-events/2021/miach-orthopaedics-announces-us-commercial-availability-of-bear-implant-to-treat-acl-tears/">press release</a>. The groundbreaking device, made of bovine collagen and a drop of the patient's blood, bridges the gap between the torn ends of the ACL. After a minimally invasive procedure to insert the implant, it can heal the ACL faster and with better patient satisfaction than a reconstruction.<h2>A new yeast infection pill</h2><div type="image" title="yeast infection" height="1466" width="1955" msid="88523955" hostid="261"></div>Scientists recently developed the first new antifungal drug in more than 20 years to block the growth of Candida, the fungi involved in vaginal yeast infections.Over-the-counter treatments for yeast infections work in most cases; however, stubborn cases sometimes persist. A brand-new treatment called <a href="https://www.scynexis.com/news-media/press-releases/detail/264/brexafemme-ibrexafungerp-tablets-receives-2021-popular">Brexafemme</a> offers a departure from existing antifungals. Brexafemme works by blocking the creation of a protective coating around the fungi, causing the bug to die off. The medicine remains in the system for as long as two weeks to prevent the infection from returning, according to a press release.The drug is now available as a two-tablet formulation to be prescribed by healthcare providers.<h2>A close-to-human breast milk formula</h2><div type="image" title="nurse holding bottle of breast milk" height="2699" width="3598" msid="88523958" hostid="261"></div>Two female scientists made the first lab-grown batch of breast milk this year, and it could eventually be a solution for parents who cannot or choose not to breastfeed.<a href="https://www.biomilq.com/">Biomilq</a> is the first cell-cultured milk with the nutritional components and complexity of breast milk, <a href="https://www.insider.com/biomilq-scientists-make-human-breast-milk-in-lab-2021-6">Insider reported in June</a>. It's made from mammary cells grown in a lab, rather than adding up ingredients to make something similar to the real thing.While Biomilq may be more nutritionally complex than formula, the founders don't claim that it's an exact replacement for breast milk. It cannot reflect a mother's diet or pass on important immune protections from the parent to child. However, it will offers an alternative to formula when it reaches the market.The founders previously told Insider they expect Biomilq will be available to consumers in about three years. After more research and approval from regulators, they also hope to bring the cost down to make the breast milk product financially accessible.

The 6 most mind-blowing human health discoveries of 2021

He's 80 and going stronger than ever, spooling in celluloid miles' with the roles rolling in and directors still lining up to sign him on. <keyword id="6357912" type="General" weightage="20" keywordseo="Amitabh-Bachchan" source="Orion">Amitabh Bachchan</keyword>, they say, was and is still an exciting actor, perhaps the best there ever has been. From Ramesh Sippy who directed him in the 1975 cult film <keyword id="6407374" type="General" weightage="50" keywordseo="sholay" source="Orion">Sholay</keyword> to Ayan Mukerji who helmed his latest Brahmastra 47 years later, <keyword id="6354348" type="General" weightage="80" keywordseo="bachchan" source="Orion">Bachchan</keyword> is the man for all seasons and all kinds of films. "What a wonderful innings it has been and he just keeps getting better. He has played so many varied roles in comedy, drama, romance, dancing and songs. He can do anything and everything perfectly. Has there been anybody bigger or better? I doubt it, Sippy told PTI as the star celebrates his 80th birthday on Tuesday. It's been just five days since his latest release Goodbye . "For me, to have Mr. Bachchan walk in my film is a big deal. He is the father of Indian cinema. He is the most respected person in the film industry, Mukerji added. Making his debut with the relatively low profile Saat Hindustani in 1969, remembered all these years primarily for serving as his launchpad, Bachchan exploded on the silver screen with <keyword id="31017" type="General" weightage="50" keywordseo="zanjeer" source="Orion">Zanjeer</keyword> in 1973. There was no looking back after that, and storytellers across five decades are still trying to decode the success of the man who keeps on reinventing himself - the angry young man' of Zanjeer , Don and Deewaar , the amiable, fun professor of Chupke Chupke and the conflicted singing star of Abhimaan in the 1970s. Then came the 1980s with films such as Shakti and Silsila . The 1990s saw a slump in Bachchan's career and many of films, including "Mrityudata" and "Lal Baadshah", tanked at the box office. Bachchan was back in the reckoning the following decade as a television host in Kaun Banega Crorepati in 2000. Twenty-two years later, the show is still running. This is also the time Bachchan transitioned into age appropriate characters in films. It started with Mohabbatein and continues with varied roles, be it Pink , Cheeni Kum or Jhund . Sippy recalled the casting for Sholay , which saw Bachchan and Dharmendra as two friends thick as thieves . "I had seen two of his earlier films -- Anand' in which he played a serious role, it was a difficult role and he stood out, and Bombay to Goa', where he played a lighter and a more boisterous role, which had impressed me a lot. We signed him. A few months later "Zanjeer" and "Deewar" released. By the time "Sholay" came, he was the rising star, the veteran filmmaker added. Sippy, who also worked with Bachchan in "Shakti", "Shaan" and "Akayla", said it is exciting to see the megastar recreate magic on screen, both the big and small even after all these years. There have been a lot of fine actors and there is absolute respect for all but he definitely stands above, he said.They may be in awe of him, but all of Bachchan's directors have experimented with the roles they offered him. R Balki, who first worked with Bachchan on an advertisement campaign, gave him "Cheeni Kum", where Bachchan is a 60-something arrogant chef romancing a much younger Tabu, and Paa that sees the star playing a 12-year-old boy afflicted with progeria. "Every filmmaker thinks of Mr Bachchan first, everybody would love to get a chance to work with him. We all came to the cinema being his fans. I was luckier than some people. I write my films for him. I have been searching for my next film for some years now," Balki told PTI. The filmmaker's other ventures -- Ki &amp; Ka , Pad Man and Chup: Revenge of the Artist -- feature the veteran star in a special appearance. There is one word to describe Amit ji and it is Amitabh Bachchan. There are no other words... It has become like a character itself. It has so much meaning, you can say persona, dignity, grace, powerful, voice, performance, everything being put together. There is a character called Amitabh Bachchan. That character is a rare phenomenon, Balki said. For new-age directors -- Ayan Mukerji and Ribhu Dasgupta -- the opportunity to direct Bachchan is nothing short of a dream. While Mukerji cast Bachchan as a guru in his astraverse, sci-fi film, Dasgupta directed Bachchan in the TV series "Yudh" (2014) and 2016 mystery-thriller Te3n . Dasgupta has tried hard to keep his fan boy self out of the picture. I come from Kolkata and we worship him there. There is an Amitabh Bachchan temple in Kolkata. But when I directed him, I had to keep the fan boy out. Also, sir knows everything, where the camera should be, what and where the light should be, etc. He sees what the person in front is doing," Dasgupta said. This year, Bachchan has already had three theatrical releases -- Nagraj Manjule-directed Jhund , Ajay Devgn's Runway 34 and Brahmastra . His latest film "Goodbye", directed by Vikas Bahl, opened on Friday. He is now awaiting the release of "Uunchai", directed by Sooraj Barjatya SEE ALSO: <a href="https://www.businessinsider.in/tech/mobile/news/google-pixel-7-and-pixel-7-pro-with-tensor-g2-chipset-launched-in-india-starting-at-59999/articleshow/94696867.cms">Google Pixel 7 and Pixel 7 Pro with Tensor G2 chipset launched in India starting at ₹59,999</a> <a href="https://www.businessinsider.in/business/telecom/news/reliance-jio-and-airtel-5g-prices-may-be-affordable-for-now-but-expected-to-increase-after-wider-rollout/articleshow/94636173.cms">Reliance Jio and Airtel 5G prices may be affordable for now but expected to increase after wider rollout</a>

Amitabh@80: Still a delight, keeps getting better, say directors old and new

<div class="KonaFilter image-container display-table float_right"><div><div class="image on-image"></div></div></div>Like most girls her age, 13-year-old Kaylee Halko loves singing along to her favorite tunes in the bathroom. It has the best lighting in the house, which is important for Halko's purposes.Because unlike her peers, when Halko records her concert in the commode and uploads it to <a href="http://www.businessinsider.com/how-to-use-musically-2016-6">Musical.ly</a>, a fast-rising social video network, millions of fans tune in to watch.If you haven't heard of Musical.ly yet,&#xa0;it's probably because you're older than 16 or&#xa0;don't live with a teen. The app took off in 2015 and today, 50%&#xa0;of teens in the US have downloaded it, <a href="http://www.businessinsider.com/teen-stars-on-musically-2016-7">according to Alex Hoffman, president of Musical.ly North America</a>.The app allows people to&#xa0;upload 15-second videos of them dancing, performing comedy skits, or lip-syncing to today's top hits, and it's&#xa0;<a href="http://www.businessinsider.com/teen-stars-on-musically-2016-7">given rise to&#xa0;the next generation of social media stars</a>.&#xa0;While most middle schoolers are worrying about zits and exams, overnight celebrities like Halko are learning to juggle international stardom with real life.<div></div>Halko has never been your&#xa0;typical American girl. Halko has&#xa0;a&#xa0;rare and fatal disease called <a href="http://www.progeriaresearch.org/about_progeria/">progeria</a>, which makes her body age up to 10 times faster than normal children. She stands less than&#xa0;four feet tall, with a smooth head and radiant blue eyes. Her voice sounds like tiny jingle&#xa0;bells.Typically, people&#xa0;born with progeria show no signs until the age of two, when they start to exhibit growth failure, loss of body fat and hair, aged-looking skin, and stiffness&#xa0;in the joints.&#xa0;On average, they die at 14, often of a heart attack or stroke.There are <a href="http://www.progeriaresearch.org/meet_the_kids/">135 known children</a> in the world currently living with progeria. But only one&#xa0;is a rising social media star.Growing up in suburban Ohio&#xa0;with three older brothers, Halko became the confident, fearless one in the clan. She <a href="http://abcnews.go.com/Health/children-living-progeria-inside-world/story?id=14182279">always&#xa0;insisted</a>&#xa0;on taking the bus to school.&#xa0;She took dance classes in jazz, lyrical, hip-hop, and musical theater, and&#xa0;continues to enter dance competitions.<div> </div>When she was 8, she <a href="http://abcnews.go.com/Health/children-living-progeria-inside-world/story?id=14182279">appeared</a> on ABC's "20/20" and explained to&#xa0;Barbara Walters what&#xa0;the biggest difference between them was: "I have a bald head and you have hair," she said.Around the same time as her national news debut, Halko became a victim of bullying in her elementary school. A couple students <a href="http://www.wtol.com/story/25910506/bullied-student-leaving-anthony-wayne-schools-school-board-looks-for-solution">created Instagram hate pages</a> targeting her disease."It pretty much said, 'We need to kill all kids with progeria,' and, 'I want to see all these f-----g kids die,'" Halko's father, Tim, <a href="http://www.wtol.com/story/25910506/bullied-student-leaving-anthony-wayne-schools-school-board-looks-for-solution">told a local news station</a>.When they complained to the&#xa0;administration, the school forced the students to delete the pages. They <a href="https://iheartglasscity.com/2014/06/11/update-kaylee-halkos-father-shares-heartbreaking-details-about-her-bullying-warning-this-will-hurt-your-heart/">popped back up</a> a day later. Eventually, Halko transferred to another school.A year ago, when Halko's cousin&#xa0;showed her what Musical.ly was, she downloaded the app and didn't think much of it. Halko&#xa0;started spending 15 minutes a day creating lip-syncing videos that show her&#xa0;bopping along to her favorite hip-hop and dance tunes,&#xa0;serenading the camera in her&#xa0;bathroom.<div> </div>Halko has since racked up over three million followers and a dozen fan pages on Musical.ly. She almost always cracks&#xa0;the top 25 leaderboard, a list of the most liked users on the app&#xa0;day. And on any&#xa0;post, there are thousands of&#xa0;comments complimenting her eyes, her taste in music, and her spirit.For every bully that calls her a name, a flock of fans bury the comment with positive replies.<div class="KonaFilter image-container display-table"><div><div class="image on-image"></div></div></div>"I definitely feel [supported] because I've gotten a lot of nice comments and stuff," Halko tells Business Insider. "They are definitely nice, so that makes me feel good."She says she&#xa0;will often respond to direct messages from fans and doesn't mind posing for selfies in public. On a trip to South Carolina, she was ambushed for photos on the beach, in the store, and at a café. Fans often&#xa0;ask to take photos with her, but are too starstruck to strike&#xa0;up a conversation. Halko is happy to chat, and&#xa0;doesn't mind their nervousness.Just don't expect her&#xa0;to talk about progeria on Musical.ly. Halko&#xa0;doesn't make her disease&#xa0;part of the conversation, because that's not why she's on the app. She's here to have fun."Like, I don't want followers to follow me just because I have progeria," Halko says. "I want them to follow me because they like me."That they do. <div class="margin-top"> <h3>NOW WATCH: <a href="http://www.businessinsider.com/teen-beyonce-predicted-her-future-2016-5">16-year-old Beyoncé basically predicted her own future</a></h3> <div> <div> <div class="ooyala-video-player" data-video-autoplay="false" data-video-id="A4ZWJlMzE6rU0GZ7Yd0iQC1RVALNyuK3" data-player-variable="ooyalapopvideo" id="ooyalaplayer_popvideo" style="width:1280px;height:720px"></div> </div> </div> </div>

This teen went from getting bullied in school to being a Musical.ly star with millions of fans

<keyword id="6357912" type="PERSON" weightage="20" keywordseo="amitabh-bachchan">Amitabh Bachchan</keyword> is not only an actor but an inspiration to many people across the country. He has seen the best and the worst and has yet maintained a demeanor that appeals to one and all. BI India lists down five life lessons that every entrepreneur can learn from this versatile actor. 
	 
	Be strong 
	 All was not smooth for this icon when he had begun his career forty years ago. His deep voice was rejected by <keyword id="84486" type="COMPANY" weightage="20" keywordseo="All-INdia-radio">All India Radio</keyword> and movie makers rejected him because of his height. And even after he debuted in Bollywood, a string of flops marred his career prospects. Bachchan, however, remained strong and determined to make a mark in the industry. He took up roles that were secondary to the lead roles only to stay in the limelight. The fact that he went through a lot of hardships before becoming successful is definitely a point to remember for not just entrepreneurs but everyone who aspires to be one. 
	 
	Never Lose Hope 
	 
	The man tasted immense success in the 80’s and then came a period that would give any man jitters. He was out of work, his company had gone kaput, he was embroiled in legal battles along with the authorities hounding him for recovery of taxes. However, Amitabh Bachchan did not lose hope. Instead, he at the age of 57, went looking for work. His positive attitude has helped him sail through difficult times. His optimism makes it the second important life lesson that every entrepreneur should learn from this superstar. 
	 
	Value everyone 
	 
	Amitabh Bachchan is probably the only actor who can connect with the youngest to the oldest person in a room. And while many call it his charisma, BI believes that the fact that he values everyone around him makes him the most favourite among generations. His down to earth personality has enamoured many people across the world, which truly makes him a people’s man. This is a rare trait, which if practiced by every entrepreneur, can make him grow leaps and bounds. 
	 
	Never Say Never 
	 There is a reason why Amitabh Bachchan was chosen to play Auro, a 12 year old boy with a rare genetic disorder called progeria, in the blockbuster <keyword id="51400" type="ENTERTAINMENT" weightage="20" keywordseo="paa">Paa</keyword>. The man is not just known for his versatility but also for the fact that he is ready to experiment even at this stage of his career. His receptiveness to new ideas and the fact that he understand it is important to change with times has only added to his brand appeal. We believe this is an extremely important characteristic that every entrepreneur should practice not only in his business but also in other sphere of his life. 
	 
	Have a nook of your own 
	 
	Lastly, it is extremely important to create your own niche in whichever industry you belong to. Amitabh Bachchan with his deep voice had created an angry young man image, which people still remember. So whatever you do, ensure you do it differently because that helps you make a mark in people’s mind.

5 Life Lessons
To Learn From Amitabh Bachchan

<keyword id="6357912" type="PERSON" weightage="20" keywordseo="amitabh-bachchan">Amitabh Bachchan</keyword> is not only an actor but an inspiration to many people across the country. He has seen the best and the worst, and has yet maintained a demeanor that appeals to one and all. BI India lists down five life lessons that every entrepreneur can learn from this versatile actor. 
	 
	Be Strong 
	 
	Life was not smooth for this icon when he began his career forty years ago. His deep voice was rejected by All India Radio, and movie makers rejected him because of his height. And even after he debuted in Bollywood, a string of flops marred his career prospects. Bachchan, however, remained strong and determined to make a mark in the industry. He took up roles that were secondary to the lead roles only to stay in the limelight. The fact that he went through a lot of hardships before becoming successful is definitely a point that not just entrepreneurs but everyone who aspires to be one should remember. 
	 
	Never Lose Hope 
	 
	The man tasted immense success in the 80s and then came a period that would give any man jitters. He was out of work, his company had gone kaput, he was embroiled in legal battles and had authorities hounding over him for tax recovery. However, Amitabh Bachchan didn’t lose hope. Instead, he at the age of 57, went looking for work. His positive attitude helped him sail through difficult times. Optimism, patience and perseverance are what every entrepreneur should learn from this superstar. 
	 
	Value Everyone 
	Amitabh Bachchan is probably the only actor who can connect with people from all age groups—right from the toddlers to youngster to aged. And while many call it his charisma, BI believes that the fact that he values everyone around him, which makes him the most favourite among generations. His down to earth personality has enamoured many people across the world, and truly make him people’s man. This rare trait, if practiced by every entrepreneur, can make him grow leaps and bounds. 
	 
	Never Say Never 
	 There is a reason why Amitabh Bachchan was chosen to play Auro, a 12 year old boy with a rare genetic disorder called progeria, in the blockbuster <keyword id="51400" type="ENTERTAINMENT" weightage="20" keywordseo="paa">Paa</keyword>. The man is not just known for his versatility, but also for the fact that he is ready to experiment even at this stage of his career. His receptiveness to new ideas and the fact that he understand it is important to change with times has only added to his brand appeal. We believe this is an extremely important characteristic that every entrepreneur should practice not only in his business but also in other spheres of life. 
	 
	Have A Nook Of Your Own 
	 
	Lastly, it is extremely important to create your own niche in whichever industry you belong to. Amitabh Bachchan with his deep voice had created an angry young man image, which people still remember. So whatever you do, ensure you do it differently because that helps you make a mark in people’s mind.

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