Best printers for Home

Best Mixer Grinder

Best wired Earphones

Best 43 Inch TV in India

Best Wi Fi Routers

Best Home Theatre in India

Smart Watch under 5000

Best Laptops for Education

Best Laptop for Students

<ul class="summary-list"><li>Musical maven <keyword id="365825" type="COMPANY" weightage="60" keywordseo="Lizzo">Lizzo</keyword> recently hopped on to a <keyword id="6762469" type="UNKNOWN" weightage="60" keywordseo="TikTok">TikTok</keyword> trend to highlight <keyword id="4996556" type="PERSON" weightage="60" keywordseo="body-positivity">body positivity</keyword> and self-love in the face of misleading social media aesthetics. </li><li>The trend usually calls out how different poses and angles can be used to create unrealistic beauty standards by hiding belly rolls or cellulite and accentuating curves or muscles.</li><li>Lizzo used the trend to showcase her body from all angles, even while it changes.</li><li>With it, she posted a shout-out to the "big girls" who helped make body positivity a popular movement. </li></ul>Lizzo turned a popular TikTok trend on its head in tribute to the flourishing body positivity movement.The pop superstar posted a video of herself in a white bikini from all angles, encouraging fans and followers to do the same. It was set to an audio narration from TikTok user MaryCjSkinner, which many models and personal trainers have used to compare careful posing with normal stature - explaining that "bodies that look like this... also look like this."Typically, all-angles videos demonstrate how certain poses can highlight curves or muscles while others can reveal belly rolls or cellulite.Lizzo used the audio in a video to showcase her body, without contorting herself at all - simply showing off her belly, back, and legs from different perspectives. "Wild to see the body positive movement come so far. Proud of the big girls who gave it wings," Lizzo wrote in the caption.The response from her audience was overwhelmingly positive. Many people posted to say they felt Lizzo's confidence and self-love empowered them to be kinder to themselves. "I'm lucky to be a big girl in the era of Lizzo" one fan wrote in a reply on Instagram. The 'angles' trend is part of a larger movement on Instagram and TikTok to point out unrealistic body image standards. Social media is prone to a deluge of <a href="https://www.insider.com/fitspiration-doesnt-work-but-worsens-body-image-self-esteem-study-2020-3">toned, tanned models, which can fuel feelings of anxiety and inadequacy</a> from viewers. While this can be true regardless of size, people with larger bodies can be especially vulnerable because of how popular culture stigmatizes weight and body fat. That's prompted <a href="https://www.insider.com/plus-size-woman-criticizes-slim-influencers-too-much-space-body-positivity-2020-5">advocates to speak out against some slimmer influencers' use of the trend</a>, arguing that they are disproportionately benefiting from a movement that was started by people (often women) with larger bodies who risked harassment and trolling to do so.Activists have also pointed out that the <a href="https://www.mayaesthetic.com/home/body-positivity-racism">body positivity movement has to reconcile with racism as well</a>, since beauty standards often privilege white, Eurocentric aesthetics that further marginalize people of color. Lizzo has previously used her platform to consistently address both <a href="https://www.insider.com/every-time-lizzo-said-something-that-makes-you-feel-good-2020-7">fatphobia</a> and <a href="https://www.billboard.com/articles/news/9394311/lizzo-racism-violence-minneapolis-protests-instagram-live-recap">racism</a>, as well as other diversity issues like <a href="https://www.advocate.com/exclusives/2020/5/21/lizzo-continues-flame-torch-black-queer-artists">LGBTQ rights</a>. Read more:<a href="https://www.insider.com/every-time-lizzo-said-something-that-makes-you-feel-good-2020-7">7 times Lizzo said something that makes you feel good about your body</a><a href="https://www.insider.com/lizzo-vegan-diet-review-good-recipes-gassy-groggy-too-expensive-2020-7">Lizzo's vegan diet left me groggy and gassy, but I loved her hangover brunch</a><a href="https://www.insider.com/plus-size-woman-criticizes-slim-influencers-too-much-space-body-positivity-2020-5">A plus-sized woman criticized slimmer influencers for 'taking up too much space' in the body positivity sphere, and it sparked a huge debate</a>

Lizzo posted an 'all-angles' TikTok video to celebrate the rise of the body positivity movement, and the 'big girls who gave it wings'

7 times Lizzo said something that makes you feel good about your body

<ul class="summary-list"><li>I was tired of hearing my children complain every day, so I started asking them one simple question.</li><li>"Can you tell me one good thing about your day?" I'd ask. No one could leave until we all answered.</li><li>It has brought our family together in a way I never anticipated. </li></ul>I'm willing to listen to my two kids vent about their day - to hear them whine, complain, and talk through their struggles. But after a while, I noticed they'd <a href="https://www.businessinsider.com/why-negative-thinking-can-help-you-successfully-make-decisions-2020-10">spiral into a loop of negativity</a> that started when I picked them up from school and continued until bedtime.In an attempt to pull them out of that pattern, I started asking one simple question every night at dinner. No one could leave the table until we all answered it, myself and my husband included."Can you tell me one good thing about your day?"Sometimes the answer was no. <a href="https://www.businessinsider.com/nine-thinking-patterns-that-are-holding-you-back-and-how-to-stop-them-2018-9">So I would listen to the annoying</a>, stressful, and sometimes genuinely terrible parts of their day.Still, I firmly believe that even on the most dreadful of days, we can find one good thing that happened. Even if it took a while, they'd find something.<h2>I tried to get them to focus on the good things</h2>I saw that focusing on something good - even just one small thing - <a href="https://www.insider.com/how-to-think-positive">helped change their tone and shift their mindset</a>.As weeks stretched into months of my asking the same question every night, this difference got bigger. I noticed my kids would start looking for "good things" throughout the day just so they'd have something to share at dinner. Surprisingly, my husband and I did it, too.I knew we hit a sweet spot when one of my boys announced, "I had three good things today!" Sure, sometimes those things would be breakfast, lunch, and dinner. But it went deeper, too.<h2>I learned things about my kids I would've otherwise never known</h2>I was delighted to learn about a classmate who helped my son with a tricky math problem, the big dodgeball victory in gym class, and how much my child adored his first-ever Hostess cupcake, which a friend had brought in for their birthday.Without asking that nightly question, I don't think I would've ever known any of this.Every now and then I'd get an answer like "My only good thing was when the bell rang at the end of the day." Sometimes I'd make them try again. But occasionally I'd let it slide, especially on those toughest of days.As we inched toward Thanksgiving, I expanded the question to include something they were thankful for. The kids groaned a little at first. But again, I was pleasantly surprised by the results.Even the most dedicated gamer - my youngest boy, who's 13 - didn't say he was thankful for his Xbox or an upcoming game release. No one even listed their computer or tablet. Only once did someone say WiFi.I learned that my youngest is more philosophical than I give him credit for: He's thankful for oxygen and electricity (though maybe he was just learning about those in science that day).Mostly our highlights were simple, everyday pleasures. Time with friends. Tacos. A clean garage. Fuzzy blankets. A new book. The rock-climbing gym. Rice with dinner. A cuddly puppy.But the best part about asking that question every night was that it got us talking. It put us in a thankful mindset, and we learned a little something about each other that we may have never known otherwise.For me, that newfound connectedness is at the very top of my list of good things.

I ask my family the same question every night. It's made us more positive and connected.

<ul class="summary-list"><li>A <keyword id="177121" type="PERSON" weightage="60" keywordseo="long-position">long position</keyword> involves using <keyword id="43774" type="PERSON" weightage="60" keywordseo="Options">options</keyword>, which let you lock in a stock's price for a future transaction.</li><li>Long <keyword id="610748" type="PERSON" weightage="60" keywordseo="call-options">call options</keyword> and long <keyword id="1074050" type="PERSON" weightage="60" keywordseo="put-options">put options</keyword> give you the right to buy or sell a stock, respectively. </li><li>Long positions hedge risk: If the stock doesn't move as hoped, the option expires at little cost.</li></ul>In the investing world, "long" is a word loaded with meaning. <keyword id="10695933" type="UNKNOWN" weightage="60" keywordseo="taking-a-long-position">Taking a long position</keyword>, or going long, generally refers to an investor owning an asset - like a stock - because they believe it will appreciate. They are holding it for an extended period, the long-term - hence, "going long." But a long position also has a specialized meaning, having to do with <a href="https://www.businessinsider.com/what-is-options-trading" target="_blank" rel="noopener">options trading</a>. It's a strategy that lets you make a bet, based on whether you believe a stock (or another asset) will rise or fall in value - generally, rise. If an options trader says "I am long Microsoft," it often means they have a <a href="https://www.businessinsider.com/what-is-a-bull-market" target="_blank" rel="noopener">bullish</a>, or optimistic, view of Microsoft's performance. Let's examine all the permutations of long positions in options.<h2>Fast facts about options</h2><ul><li>An option is a contract giving you the right - but not the obligation - to buy or sell an asset (usually a stock) at a specific price before a specific date.</li><li>Options come in two basic varieties. An option to buy is a call. An option to sell is a put.</li><li> Options contracts are usually for 100 shares.</li><li>You don't put up any money for the stock shares, but you do pay a fee, or premium, for the option. The premium is based partly on the price at which the option-holder might buy or sell the asset - the strike price - and partly on the length of the contract. Generally, the shorter the contract and the more the strike price has to move (from the asset's current price), the lower the premium. </li><li>Options contracts usually run anywhere from one to nine months.</li></ul><h2>What is a long position?</h2>A long position in options conveys the right to buy or put sell shares for a preset price on or before a future date.There are two types of long options, a long call and a long put. A long call option gives you the right to call, or buy, shares of a named stock for a preset price at a later date.A long put option does the opposite: It gives you the right to put, or sell, shares of that stock in the future for a preset price.<h2>Purchasing a long call option</h2>If you believe a certain stock is going to go up in price in the coming days, weeks, or months, you can purchase a long call option to buy that stock for today's price sometime in the future and make a profit by selling it on the stock market at the then- higher price.Example: You believe ABC stock, selling today for $100 a share is going to be worth more in a couple of months. You purchase a long call option contract for 100 shares, set to expire in three months, with a contract (strike) price of $100 per share, and a fee (premium) of $3 per share.ABC does as you expect and in two months shares are worth $150 apiece. You exercise your option, buy 100 shares at $100 each, sell them for $150 each, and you've made a tidy profit of $4,700.Here's the math:$15,000 from the sale of 100 shares @ $150 on the stock market- $10,000 cost to buy those shares at the strike price- $300 cost of the original contract premium= $4,700 profit<h2>Purchasing a long put option</h2>If you believe a company's stock will lose value in the future, you would purchase a long put option contract giving you the right to sell shares of that stock in the future for today's (higher) price.Example: You believe ABC's stock is going to be lower in a couple of months. You purchase a long put (sell) option contract for 100 shares, set to expire in three months, with a strike price of $100 per share, and a premium of $3 per share.ABC does as you expected and in two months shares are selling for $50. You buy 100 shares at $50 each, exercise your option, and sell them for $100 each, and you've made a tidy profit of $4,700.Here's the math:$10,000 from the sale of 100 shares @ $100 strike price- $5,000 cost to buy those shares at the lower market price- $300 cost of the original contract premium= $4,700 profit<h2>Exercising your option</h2>You can't make money buying either a long call or long put option unless you exercise your option. Exercising your option means to buy or sell before the expiration date set in the option contract. Naturally, you'd exercise the option if things go the way you expect - the stock moves in the way you thought it would, hitting the strike price.Why would you let the option expire without exercising it? Simple: The price of the stock goes against your prediction, moving in an opposite direction from the strike price. If that happens, the option becomes worthless. You let it expire, and you lose the premium you paid. The good news is, that's all you lose.<h2>Why take a long position?</h2>For those who like to trade, going long lets you take chances with less risk. Both long calls and long puts limit your loss to the cost of the options contract. When buying or short-selling a stock outright, you stand to lose much more money (see below).Long options also include an unlimited profit potential to the upside in the case of a long call option or the downside with a long put option. Best of all, long option positions require less of an investment or cash down. Instead of spending thousands on a stock, you just spend a few hundred on the option, giving you more leverage for less money.<h2>What is a short position?</h2>A short position is the opposite of a long position. While a long position involves buying a stock (or an option to buy) that you expect to be worth more in the future, taking a short position - aka selling short or shorting a stock - involves selling a stock you don't actually own that you expect to drop in price later.Instead of buying the stock, you borrow it (and pay interest on the loan, a process called buying on <a href="https://www.businessinsider.com/what-is-margin-trading-how-it-works" target="_blank" rel="noopener">margin</a>), sell it, and put the money aside. After the price has dropped, you buy the stock back and return it to the original owner, keeping the difference as profit. Quick lingo lesson: A long put is a way of shorting a stock. Regular short-selling can be dangerous: You must buy the stock back to repay the lender, and if its price rises instead of falls, you may be out of pocket in a big way. But when you do it as an option (long put) you only risk the premium - the cost of the option. <h2>The financial takeaway</h2>With options, a long position refers to either:<ul><li>a long call option, meaning the buyer expects an underlying asset to increase in price, which increases the value of the option. </li><li>a long put option, meaning the buyer expects the underlying asset to decline in price, which also increases the value of the put option.</li></ul>Overall, long options are a bullish (optimistic) strategy in which a long call bets the underlying stock will rise and a long put serves as insurance in case it doesn't.Of the two, the long call is more common. But both are bullish strategies, in the sense that you are buying the option in the hope it'll prove valuable - and help you make more of a profit on a stock than you would by buying outright.<h2>Related Coverage in <a href="https://www.businessinsider.com/investing-reference" target="_blank" rel="noopener">Investing</a>:</h2><h3><a href="https://www.businessinsider.com/what-is-buying-the-dip" target="_blank" rel="noopener">'Buy the dip' means purchasing a promising stock when its price drops, assuming a fast rebound and future profits</a></h3><h3><a href="https://www.businessinsider.com/how-to-diversify-portfolio" target="_blank" rel="noopener">How to diversify your portfolio to limit losses and guard against risk</a></h3><h3><a href="https://www.businessinsider.com/what-is-a-margin-call" target="_blank" rel="noopener">A margin call means your broker is asking you to repay the money it lent you to buy stocks - and if you don't, it could mean big losses for your portfolio</a></h3><h3><a href="https://www.businessinsider.com/trading-vs-investing" target="_blank" rel="noopener">Trading and investing are two approaches to playing the stock market that bring their own benefits and risks</a></h3><h3><a href="https://www.businessinsider.com/value-investing-definition" target="_blank" rel="noopener">Value investing is a bargain-hunting strategy that targets low-performing but quality stocks, aiming to profit when their prices rise again</a></h3>

A long position is a trading strategy that can help you profit from a stock, whether its price rises or falls

<keyword id="3001" type="LOCATION" weightage="20" keywordseo="Pakistan">Pakistan</keyword> <keyword id="71" type="POSITION" weightage="20" keywordseo="Prime-Minister">Prime Minister</keyword> <keyword id="14676" type="PERSON" weightage="20" keywordseo="Imran-Khan">Imran Khan</keyword> has tested <keyword id="6439681" type="UNKNOWN" weightage="20" keywordseo="positive">positive</keyword> for the novel coronavirus. Faisal <keyword id="6355056" type="COMPANY" weightage="20" keywordseo="Sultan">Sultan</keyword>, Special Assistant to the Prime Minister on National Health Services, Regulations &amp; Coordination confirmed the development on Saturday. Sultan said that the 68-year-old former cricketer-turned-politician has quarantined himself at home. "PM Imran Khan has tested positive for Covid-19 and is self isolating at home," Sultan said in a tweet. Pakistan is using the Chinese vaccine, Sinopharm against Covid-19 pandemic. Recently a batch of 5,00,000 doses was received in Pakistan from China. The vaccination drive in Pakistan is currently underway for senior citizens. SEE ALSO: <a href="https://www.businessinsider.in/stock-market/news/easemytrip-ipo-listing-price-at-13-5-premium/articleshow/81581828.cms">EaseMyTrip lists at 13.5% premium – but gives up some of the listing gains soon after</a> <a href="https://www.businessinsider.in/tech/mobile/news/oneplus-9-pro-specs-oneplus-9e-specs-and-price-leak-and-oneplus-9-series-launch-date/articleshow/81168227.cms">OnePlus 9 series specifications and features leaked – here's everything we know about the upcoming OnePlus smartphones</a> <a href="https://www.businessinsider.in/tech/mobile/news/checkout-review-of-moto-g10-power-mobile-phone-review-and-features-information/articleshow/81583548.cms">Moto G10 Power mobile review – big battery on a shoestring budget</a>

Pakistan PM Imran Khan isolates after testing COVID-19 positive

<keyword id="271" type="POSITION" weightage="20" keywordseo="actor">Actor</keyword> <keyword id="6381730" type="PERSON" weightage="20" keywordseo="govinda">Govinda</keyword> has tested <keyword id="6439681" type="UNKNOWN" weightage="20" keywordseo="positive">positive</keyword> for coronavirus and is currently under <keyword id="58995" type="PERSON" weightage="20" keywordseo="Home-quarantine">home quarantine</keyword>. The actor said he is under able medical guidance. He tested positive on Sunday morning and urged everyone who came in contact with him recently to get themselves tested. Talking to IANS about his health, the actor said: "I have been testing myself and taking all the necessary precautions to keep the coronavirus away. However, I tested positive today following mild symptoms. All others at home have tested negative. Sunita (wife) has just recovered from Covid-19 a couple of weeks back." The actor added: "I am under home quarantine and under able medical guidance. I request everyone to please follow all the necessary precautions and please take care." Earlier on Sunday, actor <keyword id="2823" type="PERSON" weightage="20" keywordseo="Akshay-Kumar">Akshay Kumar</keyword> also updated his fans that he has tested positive for the virus. SEE ALSO: <a href="https://www.businessinsider.in/science/space/news/nasa-estimates-pandemic-could-cost-it-around-3-billion-quick-look-at-projects-to-take-the-biggest-hit/slidelist/81869940.cms">NASA estimates the pandemic ballooned costs by $3 billion — here are the projects to take the biggest hit</a> <a href="https://www.businessinsider.in/business/startups/news/a-5-5-billion-british-fintech-start-up-may-have-200-jobs-to-offer-in-india/articleshow/81867620.cms">A $5.5 billion British fintech start up may have 200 jobs to offer in India</a> <a href="https://www.businessinsider.in/business/startups/news/for-revolut-india-is-just-the-first-in-a-series-of-countries-it-plans-to-enter-in-the-next-18-months/articleshow/81883114.cms">For Revolut, India is just the first in a series of countries it plans to enter in the next 18 months</a>

Bollywood actor Govinda tests positive for COVID-19, under home quarantine

Film producer <keyword id="6356243" type="UNKNOWN" weightage="20" keywordseo="Ramesh-Taurani">Ramesh Taurani</keyword> has tested <keyword id="6439681" type="UNKNOWN" weightage="20" keywordseo="positive">positive</keyword> for Covid-19. The <keyword id="3635" type="PERSON" weightage="20" keywordseo="Filmmaker">filmmaker</keyword> shared the news on Instagram on Wednesday, informing that he has tested positive after taking the first dose of the vaccine. "I have tested positive for <keyword id="8764262" type="COMPANY" weightage="20" keywordseo="covid">COVID</keyword> and have informed BMC. I have been following all the precautions and taking medications to get better. If you have interacted with me in the past 2 weeks please do get tested. I have taken my 1st vaccine dose and hope to recover from this soon. Please wear a mask and stay safe!" Ramesh Taurani shared in an Instagram post. Several Bollywood celebrities have tested positive for the virus recently. On Wednesday, Bollywood superstar <keyword id="6355923" type="PERSON" weightage="20" keywordseo="Aamir-Khan">Aamir Khan</keyword>'s team announced that the actor has tested positive for Covid-19 and is living under home quarantine. On Monday, actor Kartik Aaryan had tweeted to inform that he has tested positive. Other Bollywood personalities who recently tested positive include actor Ranbir Kapoor, filmmaker Sanjay Leela Bhansali, actors Manoj Bajpayee, Siddhant Chaturvedi, Tara Sutaria, and actor-filmmaker Satish Kaushik. SEE ALSO: <a href="https://www.businessinsider.in/business/startups/news/peter-thiel-backed-vc-firm-valar-ventures-invests-in-indian-fintech-startup-velocity/articleshow/81663073.cms">Peter Thiel-backed VC firm Valar Ventures invests in Indian fintech startup Velocity</a> <a href="https://www.businessinsider.in/stock-market/news/anupam-rasayan-ipo-lists-at-520-per-share-on-the-india-stock-exchange/articleshow/81663145.cms">Anupam Rasayan fails to dazzle on its stock market debut – shares down by nearly 8% below the issue price</a> <a href="https://www.businessinsider.in/business/startups/news/inshorts-backed-social-networking-app-public-raises-300-crore-in-latest-funding/articleshow/81663873.cms">Inshorts-backed social networking app Public raises ₹300 crore in latest funding</a>

Film producer Ramesh Taurani tests COVID-19 positive after first dose of vaccine

Actor <keyword id="6354526" type="PERSON" weightage="20" keywordseo="alia-bhatt">Alia Bhatt</keyword> on Friday said she has tested <keyword id="6439681" type="UNKNOWN" weightage="20" keywordseo="positive">positive</keyword> for <keyword id="8763838" type="UNKNOWN" weightage="20" keywordseo="covid-19">COVID-19</keyword> and is under home quarantine. The 28-year-old actor took to <keyword id="819905" type="LOCATION" weightage="20" keywordseo="Instagram">Instagram</keyword> and posted a note, informing her fans that she is currently following all the <keyword id="332947" type="TECHNOLOGY" weightage="20" keywordseo="safety-protocols">safety protocols</keyword> listed by her doctors. "I have tested positive for COVID-19. I have immediately isolated myself and will be under home quarantine. "I am following all safety protocols under the advice of my doctors. Grateful for all your love and support. Please stay safe and take care," the "Kalank" actor wrote. Bhatt had on March 11 tested negative for COVID-19 and resumed work after her actor-boyfriend Ranbir Kapoor and filmmaker <keyword id="6358308" type="PERSON" weightage="20" keywordseo="Sanjay-Leela-Bhansali">Sanjay Leela Bhansali</keyword>, who had been shooting for "Gangubai Kathiawadi" with her, tested positive. Kapoor last week tested negative for COVID-19 while reports suggest that Bhansali has also recovered from the virus. On Thursday, Mumbai reported 8,646 new coronavirus cases, its highest one-day rise since the outbreak of the pandemic. The city's overall caseload tally stands at 4,23,360. SEE ALSO: <a href="https://www.businessinsider.in/finance/news/upi-crosses-5-lakh-crore-in-transaction-value-in-march/articleshow/81820799.cms">India’s digital payments soar – UPI crosses ₹5 lakh crore in transaction value in March</a> <a href="https://www.businessinsider.in/india/news/west-bengal-is-the-highest-contributor-to-small-savings-schemes/articleshow/81825902.cms">West Bengal is the highest contributor to small savings schemes – with elections underway, it could have been a trigger for the government to roll back interest rate cuts</a> <a href="https://www.businessinsider.in/business/startups/news/revolut-india-plan-starts-with-a-25-million-investment-and-possibly-a-fintech-acquisition/articleshow/81833983.cms">Revolut’s India plan starts with a $25 million investment and possibly, a fintech acquisition</a>

Bollywood actress Alia Bhatt tests positive for COVID-19

<ul><li>The 6-year-old mixed breed <keyword id="8312" type="PERSON" weightage="20" keywordseo="Dog">dog</keyword> was tested after its owners contracted COVID-19 and the dog began suffering from a neurological illness, the Georgia Department of Health said in a news release on Wednesday.</li><li> The dog was positive for SARS-CoV-2, the virus that causes COVID-19.</li><li>The dog was euthanized after the neurological illness progressed.</li></ul> Guidelines from the US Centers for Disease Control and Prevention say that based on the limited information available so far, the risk of pets spreading coronavirus to people "is considered to be low". (AP) NSD NSD A dog in Georgia is believed to have been the second canine in the US to test positive for the virus that causes COVID-19, health officials said. The 6-year-old mixed breed dog was tested after its owners contracted COVID-19 and the dog began suffering from a neurological illness, the Georgia Department of Health said in a news release on Wednesday. The dog was positive for SARS-CoV-2, the virus that causes COVID-19. The dog was euthanized after the neurological illness progressed. Officials said the dog's neurological illness was caused by a condition unrelated to the coronavirus. Guidelines from the US Centers for Disease Control and Prevention say that based on the limited information available so far, the risk of pets spreading coronavirus to people "is considered to be low". (AP) NSD NSD

A dog in Georgia tests positive for SARS-CoV-2

Sydney, <keyword id="6354645" type="ORGANIZATION" weightage="20" keywordseo="researchers">Researchers</keyword> have found new evidence about the <keyword id="1308746" type="PERSON" weightage="20" keywordseo="positive-role">positive role</keyword> of <keyword id="3124830" type="PERSON" weightage="20" keywordseo="androgens">androgens</keyword>, commonly thought of as male sex hormones but also found at lower levels in women, in breast cancer treatment. In normal breast development, <keyword id="10620878" type="UNKNOWN" weightage="20" keywordseo="estrogen-stimulates">estrogen stimulates</keyword> and androgen inhibits growth at puberty and throughout adult life. Abnormal estrogen activity is responsible for the majority of breast cancers, but the role of androgen activity in this disease has been controversial. The new research published in the journal <keyword id="298915" type="ORGANIZATION" weightage="20" keywordseo="Nature-Medicine">Nature Medicine</keyword> showed that androgens have potential for treatment of <keyword id="3157762" type="PERSON" weightage="20" keywordseo="estrogen-receptor-positive-breast-cancer">estrogen receptor positive breast cancer</keyword>. A cancer is called estrogen receptor positive if it has receptors for estrogen, according to Breastcancer.org. Using cell-line and patient-derived models, the global team, including researchers at the <keyword id="171120" type="COMPANY" weightage="20" keywordseo="University-of-Adelaide">University of Adelaide</keyword> and the Garvan Institute of Medical Research in Australia, demonstrated that androgen receptor activation by natural androgen or a new androgenic drug had potent anti-tumour activity in all estrogen receptor positive breast cancers, even those resistant to current standard-of-care treatments. In contrast, androgen receptor inhibitors had no effect. "This work has immediate implications for women with metastatic estrogen receptor positive breast cancer, including those resistant to current forms of endocrine therapy," said lead researcher Theresa Hickey, Associate Professor at the University of Adelaide. "We provide compelling new experimental evidence that androgen receptor stimulating drugs can be more effective than existing (e.g. Tamoxifen) or new (e.g. Palbociclib) standard-of-care treatments and, in the case of the latter, can be combined to enhance growth inhibition," said Wayne Tilley, Director of the Dame Roma Mitchell Cancer Research Laboratories, Adelaide Medical School, University of Adelaide. Androgens were historically used to treat breast cancer, but knowledge of hormone receptors in breast tissue was rudimentary at the time and the treatment's efficacy misunderstood. Androgen therapy was discontinued due to virilising side effects and the advent of anti-estrogenic endocrine therapies. While endocrine therapy is standard-of-care for estrogen receptor positive breast cancer, resistance to these drugs is the major cause of breast cancer mortality. "The new insights from this study should clarify the widespread confusion over the role of the androgen receptor in estrogen receptor driven breast cancer," said Elgene Lim, a breast oncologist and Head of the Connie Johnson Breast Cancer Research Lab at the Garvan Institute. "Given the efficacy of this treatment strategy at multiple stages of disease in our study, we hope to translate these findings into clinical trials as a new class of endocrine therapy for breast cancer." SEE ALSO: <a href="https://www.businessinsider.in/business/startups/news/zoom-dropbox-backer-salesforce-ventures-makes-its-first-investment-in-india-in-hr-tech-startup-darwinbox-which-claims-to-have-grown-by-200-during-lockdown/articleshow/80341562.cms">Zoom, Dropbox backer Salesforce Ventures makes its first investment in India in HR tech startup Darwinbox, which claims to have grown by 200% during lockdown</a> <a href="https://www.businessinsider.in/stock-market/news/home-first-finance-company-hffc-is-set-to-launch-its-1153-crore-ipo-on-january-21/articleshow/80341439.cms?upcache=2">Warburg Pincus-backed Home First Finance Company to launch ₹1,153 crore IPO on January 21</a> <a href="https://www.businessinsider.in/international/news/top-ten-likely-global-risks-in-2021-according-to-the-world-economic-forum/slidelist/80346013.cms">From climate action failure to monopoly in the tech world — the world needs to wake up to these global risks in 2021, says the World Economic Forum</a>

Male sex hormones could help in treating breast cancer, says new study

Legendary <keyword id="1520" type="POSITION" weightage="20" keywordseo="Cricketer">cricketer</keyword> <keyword id="6354267" type="PERSON" weightage="20" keywordseo="sachin-tendulkar">Sachin Tendulkar</keyword> has tested <keyword id="6439681" type="UNKNOWN" weightage="20" keywordseo="positive">positive</keyword> for COVID-19 and is currently in home isolation, according to sources close to the family. Tendulkar is one of the biggest names to have tested positive for the virus in recent times. "Sachin has got himself tested and the report has come out positive. He has isolated himself and is following all the necessary protocols," a source close to family told on Saturday. The COVID-19 cases have been on a surge in <keyword id="13126" type="LOCATION" weightage="20" keywordseo="Maharashtra">Maharashtra</keyword> and Mumbai with over 36,000 positive cases recorded on Friday. Tendulkar recently took part in the Road Safety World Series Challenge veteran's tournament in <keyword id="45327" type="LOCATION" weightage="20" keywordseo="Raipur">Raipur</keyword>. SEE ALSO: <a href="https://www.businessinsider.in/politics/elections/news/bjp-candidate-bharati-ghosh-who-is-contesting-from-west-bengals-debra-assembly-constituency-has-an-impressive-bank-balance/articleshow/81705273.cms">Bharati Ghosh, BJP's West Bengal contestant from Debra, has a robust bank balance along with a rather long rap sheet</a> <a href="https://www.businessinsider.in/politics/elections/news/checkout-the-list-of-bjp-tmc-and-congress-candidate-names-in-first-phase-west-bengal-election/articleshow/81704142.cms">The entire list and exciting facts about the 30 assembly constituencies going to polls in West Bengal on March 27</a> <a href="https://www.businessinsider.in/policy/news/government-mandates-companies-to-disclose-cryptocurrency-holdings-from-april-1/articleshow/81704174.cms">Indian companies will have to disclose cryptocurrency holdings from April 1 – industry insiders welcome decision</a>

You Searched For "positive" and got 11 results

Lizzo posted an 'all-angles' TikTok video to celebrate the rise of the body positivity movement, and the 'big girls who gave it wings'

Gabby Landsverk

7 times Lizzo said something that makes you feel good about your body

Canela López

I ask my family the same question every night. It's made us more positive and connected.

Jacqueline Miller

A long position is a trading strategy that can help you profit from a stock, whether its price rises or falls

Jim Probasco

Pakistan PM Imran Khan isolates after testing COVID-19 positive

IANS

Bollywood actor Govinda tests positive for COVID-19, under home quarantine

IANS

Film producer Ramesh Taurani tests COVID-19 positive after first dose of vaccine

IANS

Bollywood actress Alia Bhatt tests positive for COVID-19

PTI

A dog in Georgia tests positive for SARS-CoV-2

PTI

Male sex hormones could help in treating breast cancer, says new study

IANS

Sachin Tendulkar tests positive for COVID-19

PTI

Popular Keywords

Buying Guides