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<ul class="summary-list"><li>Epidermal growth factors (<keyword id="12103405" type="UNKNOWN" weightage="60" keywordseo="egf" source="Orion">EGF</keyword>) can fight wrinkles and dry <keyword id="11899253" type="UNKNOWN" weightage="60" keywordseo="skin" source="Orion">skin</keyword> similarly to retinol.</li><li>Experts say EGFs can be an alternative to retinol for people with dry or sensitive skin.</li><li>EGFs work by telling old cells to produce more collagen, reducing the appearance of aging. </li></ul><a href="https://www.insider.com/how-to-prevent-wrinkles-with-less-money-products-expert-advice-2021-8">Anti-aging ingredients</a> are some of the most important components people look for in their <keyword id="11896780" type="UNKNOWN" weightage="60" keywordseo="skincare" source="Orion">skincare</keyword> products.If you're looking to add <a href="https://www.insider.com/how-to-prevent-wrinkles-with-less-money-products-expert-advice-2021-8">anti-aging</a> elements to your skincare routine are intimidated by <a href="https://www.insider.com/excessive-botox-filler-makes-people-look-alien-plastic-surgeon-says-2021-8">Botox injections</a> and get dried out by <a href="https://www.insider.com/retinol-faqs">retinol</a>, <a href="https://www.allure.com/story/growth-factors-in-skin-care-penis-facial">epidermal growth factors (EGFs)</a> might be for you.<h2>What are EGFs?</h2>Typically found in high-end beauty products, EGFs were <a href="https://www.nobelprize.org/prizes/medicine/1986/press-release/">discovered in the 1950s</a> by two Nobel-prize winning scientists as a way to speed up wound recovery and burns. It wasn't until the early 2000s that EGFs began making their way into skincare products, <a href="https://www.allure.com/story/growth-factors-in-skin-care-penis-facial">according to Allure</a>.Growth factors act as signals for the body to produce specific components of skin, like collagen, melanin, and keratin,<a href="https://coveteur.com/2020/09/21/growth-factors-retinol-anti-aging/"> Coveteur reported. </a>The EGFs found in beauty products are made using stem cells, which can help rejuvenate older skin cells. "Research has been substantial on growth factors when it comes to reducing lines and wrinkles," <a href="https://www.bcm.edu/people/view/kim-chang/bb99d156-e9e4-11e4-8d53-005056b104be">Kim Chang</a>, a licensed medical aesthetician, told <a href="https://blogs.bcm.edu/2019/07/22/how-growth-factors-could-improve-your-skincare-routine/">Baylor College of Medicine</a>. "They also work by adding hydration and decreasing tactile roughness in the skin."Dr. Ioannis Liakas, medical director at <a href="http://www.vie-aesthetics.com/" target="_blank" rel="noreferrer noopener">Vie Aesthetics,</a> <a href="https://www.refinery29.com/en-gb/egf-skin-benefits-botox-alternative">told Refinery29</a> EGFs can also guard against the effects of pollution and sun damage, which both contribute to aging. "I would say EGF is the ultimate ingredient for repair," <a href="https://www.gloskinbeauty.com/blog/author/anna-delacruz/" target="_blank" rel="noopener noreferrer">Anna De La Cruz</a>, an educational medical aesthetician, <a href="https://www.bustle.com/style/epidermal-growth-factor-skin-benefits-anti-aging-dermatologists">told Bustle.</a>Typically, EGFs can be found in hydrating products like serums, moisturizers, and creams. <h2>How do they compare to other <keyword id="11931732" type="UNKNOWN" weightage="60" keywordseo="anti-aging" source="Orion">anti-aging</keyword> products like retinol?</h2>Similar to retinol, products that contain EGFs help increase cell turnover to reduce skincare concerns like wrinkles, fine lines, and hyperpigmentation. However, for people with sensitive skin, daily retinols can increase dryness, inflammation, or generally irritate the skin. EGFs can be more gentle on the skin than retinols, according to Liakas. "If your skin is too sensitive to tolerate retinoids, then growth factors can be a substitute to stimulate collagen, even tone, and decrease roughness with much less irritation," dermatologist <a href="https://coveteur.com/2020/09/21/growth-factors-retinol-anti-aging/">Dr. Hadley King told Coveteur</a>. But the benefits of EGFs do come as a cost, as they usually are only found in expensive, high-end beauty products. While they aren't necessary for great skin, EGFs may be a helpful addition to an existing skincare routine. "I see growth factor products as the icing on the cake if you're looking to maximize your skin-care regimen," dermatologist <a href="https://www.allure.com/story/growth-factors-in-skin-care-penis-facial">Dr. Annie Chiu told Allure.</a>

Dermatologists say people with sensitive skin should try EGFs, a less drying alternative to retinol

<ul class="summary-list"><li><a target="_blank" href="https://www.businessinsider.com/jared-isaacman-net-worth-career-spacex-polaris-dawn-2024-8">Jared Isaacman</a> led the first private space walk during SpaceX's<a target="_blank" class="" href="https://www.businessinsider.com/spacex-elon-musk"> </a>Polaris Dawn mission.</li><li>The mission broke NASA's Earth orbit record and tested new Starlink communication technology.</li></ul>Jared Isaacman's second trip to space felt different.The billionaire CEO of the payments company Shift4 made history two months ago when he opened up the hatch on a SpaceX rocketship and stepped into outer space. The moment marked the first-ever private space walk."There's nothing that's separating you from the vacuum of death other than the single-pane visor," Isaacman told Business Insider.That single-pane visor was part of SpaceX's new extravehicular activity spacesuits — which Isaacman said "essentially becomes your spaceship — that the four-person crew tested out during its nearly <a target="_blank" class="" href="https://www.businessinsider.com/spacex-polaris-dawn-mission-launch-2024-8">five-day Polaris Dawn mission</a>. In the event that anything went wrong, Isaacman and his crew member, SpaceX engineer <a target="_blank" class="" href="https://www.businessinsider.com/polaris-dawn-crew-spacex-commercial-astronauts-first-private-spacewalk-2024-9">Sarah Gillis</a>, only had about two hours of oxygen reserved."Everything in that environment is trying to kill you," Isaacman said. "The radiation, the lack of a habitable atmosphere, there's debris that's traveling at many times the speed of bullets." The hatch was open for 25 minutes, Isaacman said, during which he and Gillis each spent around eight minutes outside the capsule. The time went by quickly, he said, but they were able to complete a test matrix of three suit mobility demonstrations.Isaacman likened looking out into the unknown darkness in space to traveling overseas in the 1400s, when humans may have feared sailing off the end of the Earth or encountering some kind of mythical sea monster.He said being outside the <a target="_blank" class="" href="https://www.businessinsider.com/spacex-elon-musk">SpaceX</a> Dragon capsule felt "very different" than looking through its window, with an intensity of light coming off of Earth that "no video can capture.""You have all these extra senses kind of fusing together and you get, I think, more of an appreciation for just how hostile and unwelcoming Space is," Isaacman said.The spacewalk itself, which occurred at altitudes up to 460 miles above the Earth, went as expected. The Polaris Dawn crew carried out around 38 science and research experiments to test the impact of radiation on the human body, contributing to SpaceX's goal to learn more about long-duration human missions to Mars and beyond."The goal was to learn a lot about the mobility of the suit and was also to learn a lot about thermal regulation of the suit, big temperature swings," Isaacman said.The SpaceX mission, Isaacson's second trip to space with the rocket company cofounded by <a target="_blank" class="" href="https://www.businessinsider.com/elon-musk">Elon Musk</a>, required flying through risky radiation belts.It surpassed NASA's record for the highest Earth orbit and went further into space than humans have traveled since the Apollo 17 mission in 1972. The crew also transmitted the <a target="_blank" class="" href="https://www.businessinsider.com/photos-spacex-polaris-dawn-mission-inside-look-2024-9">first violin performance in space using Starlink</a> technology. In a Netflix docuseries about Isaacman's <a target="_blank" class="" href="https://www.businessinsider.com/spacex-inspiration4-first-space-tourists-return-to-earth-2021-9">first SpaceX mission, Inspiration4</a>, his wife describes worrying about what could go wrong. This time around, with Polaris Dawn, those concerns seemed to improve, Isaacman said."I think my family and my wife, specifically, were much more charged up and enthusiastic than they were the first time," he told BI.Isaacman attributed some of that increased ease to a successful first mission.The team prepped extensively for Polaris Dawn, spending hundreds of hours in pressurized suit testing. The SpaceX suits were tested in a vacuum chamber at NASA's Johnson Space Center, which Isaacman said was important to make sure none of the materials would "create a toxic environment or explode."<div type="image" title="A screenshot of the Polaris Dawn spacesuits" height="1326" width="1476" msid="115290972" hostid="261" sizebytes="21574"></div>Re-entry into Earth's atmosphere, even with the prep and training from SpaceX, remained a point of nervousness. If there is a problematic amount of debris damage to the heat shield or thermal protection systems, there's "no backup plan," Isaacman said.The CEO said that while he and his family recognize the risks, they keep the mindset that it's worth it.<h2 id="03e7aad8-03e7-44a4-8f3c-2af59a1d5fea">He's going back — and expects breakthroughs are 'right around the corner'</h2>Once he landed back on Earth, Isaacman went through about three days of medical tests before largely resuming business as usual.He's been on the road a lot, visiting facilities and doing debriefs, and estimates he's only slept in his bed four or five times since his journey to space.Isaacman has maintained his role as CEO, which he said helps make his work with St. Jude and SpaceX possible. Isaacman funded both Polaris Dawn and his previous mission with SpaceX. The first mission <a target="_blank" rel="noopener noreferrer" class="c-link" href="https://inspiration4.com/">raised</a> over $240 million for St. Jude and was named Inspire4 in an effort to inspire support for the hospital.His time in space isn't over yet though — <a target="_blank" class="" href="https://www.businessinsider.com/spacex-polaris-dawn-splashdown-mission-advanced-elon-musk-mars-plan-2024-9">the Polaris Program is intended to be three missions</a> mapped out over the next six to nine years, Isaacman said. He said he expects more progress on suit development in the second Polaris mission and the third will be the first crewed flight of SpaceX's Starship, the most powerful rocket system ever built that was designed to realize Musk's dreams of settling Mars.Isaacman shares the SpaceX cofounder's view that humans will be multiplanetary — and he said the technological means to make it possible are "right around the corner." He anticipates <a target="_blank" class="" href="https://www.businessinsider.com/why-spacex-starship-launch-five-huge-deal-space-travel-2024-10">fully reusable Starships becoming a tangible reality</a> within the next decade and launching on a frequent basis, whether it be every week or month. That could lead to all sorts of space-related experimentation including asteroid mining or the establishment of bases on the moon or Mars, Isaacman said.However, the challenges don't end with the formation of an off-world base — you have to ensure the astronauts maintaining it stay alive and sane, he said."Actually having a civilization that can be successful and thrive in space is a much different set of problems," Isaacman said.Roughly half the people who go to space get sick, he said. Following the landing, Isaacman said one of his SpaceX crew members experienced a minor case of spaceflight-associated neuromuscular syndrome, which impacts vision. While the symptoms subsided shortly after, he pointed to it as an example of some of the health risks people face when venturing into space.There's also never been surgery or childbirth in space, and the psychological challenges of living away from Earth, Isaacman said."You're gonna be in a bubble or living in a cave, or underground on Mars for the entire time you're there," Isaacman said. "We'll never get better than that. So there's a lot of things that need to be solved."While humans don't have it quite figured out yet, Isaacman sees a future where humans walk on Mars."We just got to proceed with caution and just make sure we get it right," Isaacman said. "And if we do, we stand to learn so much that can change the course of trajectory of humankind."

The billionaire CEO who made history with SpaceX describes facing the 'vacuum of death' in only a spacesuit

<ul class="summary-list"><li>While certain signs of <keyword id="11984175" type="UNKNOWN" weightage="60" keywordseo="aging" source="Orion">aging</keyword> are best treated with cosmetic procedures, some products can help.</li><li>There are <keyword id="11896780" type="UNKNOWN" weightage="60" keywordseo="skincare" source="Orion">skincare</keyword> products that can reduce wrinkles and fine lines, according to experts.</li></ul>The <a href="https://www.insider.com/what-is-botox-why-is-it-popular-cosmetic-procedure-wrinkles-2021-4">demand for plastic surgery</a> has boomed throughout the pandemic, according to <a href="https://www.plasticsurgery.org/news/press-releases/american-society-of-plastic-surgeons-unveils-covid19s-impact-and-pent-up-patient-demand-fueling-the-industrys-current-post-pandemic-boom">the American Society of Plastic Surgeons.</a> Botox, in particular, was ranked as the most <a href="https://www.insider.com/what-is-botox-why-is-it-popular-cosmetic-procedure-wrinkles-2021-4">popular non-invasive cosmetic procedure</a> of 2020. While certain signs of aging are best treated with cosmetic procedures, some products are proven to treat wrinkles without a needle, experts say."People think Botox and filler are <keyword id="11899253" type="UNKNOWN" weightage="60" keywordseo="skin" source="Orion">skin</keyword> treatments, but they're not. They're just a quick fix and the skin can only handle so much," celebrity facialist <a href="https://lisaharrisskinscience.co.uk/" target="_blank" rel="noreferrer noopener">Lisa Harris</a> <a href="https://www.refinery29.com/en-gb/botox-alternatives-skincare-advice">told Refinery29.</a>Products like retinol, epidermal growth factors, and vitamin C serums can reduce signs of aging by treating fine lines, making wrinkles less deep, and lightening hyperpigmentation. <h2>Microdosing retinol </h2>Often touted as the holy grail of <keyword id="11931732" type="UNKNOWN" weightage="60" keywordseo="anti-aging" source="Orion">anti-aging</keyword> skincare products by dermatologists, <a href="https://www.insider.com/retinol-faqs">retinol</a> exfoliates the skin to prevent aging. Retinol works by gently chemically peeling the skin and increasing cell turnover to reduce the appearance of wrinkles, fine lines, and dark spots. Typically, retinol is used daily before a person goes to bed. "Retinol is FDA approved for fine lines and wrinkles because it helps improve cellular turnover," <a href="http://www.russakdermatology.com/">Dr. Julie Russak</a>, an NYC-based <keyword id="11931736" type="UNKNOWN" weightage="60" keywordseo="dermatologist" source="Orion">dermatologist</keyword>, <a href="https://www.insider.com/bar-soap-toner-on-face-bad-for-acne-scarring-dermatologist-2021-10">previously told Insider</a>. "This treats many skin concerns, including acne and acne scarring as it helps to smooth out the surface of the skin and promote new healthy skin cells."While retinol can help make skin look more even, <a href="https://www.refinery29.com/en-gb/botox-alternatives-skincare-advice">Harris told Refinery29</a> it's important to not overuse it because too much can cause damage."I often repair people's skin from using too much retinol. It can cause sensitivity like redness and dryness, which can be terrible," Harris said. Harris said people should start with a low dose of retinol with a concentration of 0.2%. <h2>Epidermal growth factors (EGF)</h2>Because retinol chemically exfoliates the skin, people with sensitive skin may experience dryness and inflammation while using it. If you have sensitive skin, <a href="https://www.insider.com/epidermal-growth-factors-why-dermatologists-like-wrinkle-reducer-2021-9">epidermal growth factors (EGFs)</a> might be better catered to your skin than retinol, dermatologists say. EGFs work similarly to retinols and treat wrinkles and fine lines by <a href="https://coveteur.com/2020/09/21/growth-factors-retinol-anti-aging/">increasing cell turnover</a> to create collagen, melanin, and keratin. EGFs send signals to receptors in your skin cells to ramp up production, which can reduce the look of dark spots and wrinkles. The biggest downside to EGFs are their price, as <a href="https://www.insider.com/epidermal-growth-factors-why-dermatologists-like-wrinkle-reducer-2021-9">Insider previously reported</a> they are normally found in high end beauty products. <h2>Vitamin C</h2>Vitamin C is another preventative measure you can use to protect your skin from aging. As a common anti-aging ingredient, vitamin C can <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579659/">stimulate the production of collagen</a>, which is what keeps the skin youthful and mark-free.<a href="https://www.mayoclinic.org/diseases-conditions/wrinkles/in-depth/wrinkle-creams/art-20047463#:~:text=Vitamin%20C%20is%20a%20potent,reduce%20fine%20lines%20and%20wrinkles.">According to the Mayo Clinic,</a> adding vitamin C to your skincare regiment can lighten hyperpigmentation spots, scarring, and treat fine lines.Vitamin C is also <a href="https://www.insider.com/vitamin-c-benefits">an antioxidant</a>, which means it can protect the skin from outside pollutants that prematurely age the skin.

3 skincare products that can help you look younger without Botox, according to experts

<ul class="summary-list"><li>Preventative <keyword id="11896780" type="UNKNOWN" weightage="60" keywordseo="skincare" source="Orion">skincare</keyword> measures are crucial to beating hyperpigmentation, fine lines, and <keyword id="12713535" type="UNKNOWN" weightage="60" keywordseo="wrinkles" source="Orion">wrinkles</keyword>. </li><li>Dermatologists told Insider using SPF and properly hydrating your <keyword id="11899253" type="UNKNOWN" weightage="60" keywordseo="skin" source="Orion">skin</keyword> everyday can keep signs of <keyword id="11984175" type="UNKNOWN" weightage="60" keywordseo="aging" source="Orion">aging</keyword> away longer.</li></ul>2021 has been a stressful year for many of us – and with stress can come wrinkles.Dermatologists told Insider treating signs of aging like fine lines, hyperpigmentation, and wrinkles begins long before you develop them. Proactive skincare measures like using sunscreen to block out UV rays, properly hydrating your skin, and using <keyword id="11931732" type="UNKNOWN" weightage="60" keywordseo="anti-aging" source="Orion">anti-aging</keyword> products like vitamin C can all help maintain your skin's elasticity and fullness. <h2>Protect your skin by using SPF everyday </h2>SPF is an easy way to incorporate <keyword id="11931733" type="UNKNOWN" weightage="60" keywordseo="wrinkle" source="Orion">wrinkle</keyword> prevention into your skin routine.Dr. Gary Goldenberg, a dermatologist and <a href="https://goldenbergdermatology.com/">founder of Goldenberg Dermatology</a> in New York, <a href="https://www.insider.com/baby-wipes-hydrogen-peroxide-damaging-for-face-doctor-advice-2021-10">previously told Insider</a> SPF products block out the sun's rays, which can prematurely age your skin and cause fine lines and wrinkles.According to <a href="https://waldorfderm.com/">Dr. Heidi Waldorf</a>, a cosmetic dermatologist, <a href="https://www.insider.com/dermatologist-told-me-everything-im-doing-wrong-in-skincare-routine-2020-7">everyone should use at least 35 SPF</a> on their face to properly protect their skin. For <a href="https://www.insider.com/how-to-find-sunscreen-for-melanin-rich-skin-2020-8#:~:text=Get%20a%20minimum%20of%20SPF,the%20face%20on%20your%20skin.">people with melanin-rich skin</a>, mineral sunscreens can <a href="https://www.insider.com/alexandria-ocasio-cortez-skincare-routine-dermatologist-approved-2020-8">often leave a "white cast"</a> across the face. Chemical sunscreens and tinted mineral sunscreens could be a better option for deeper hues. <h2>Properly moisturizing plumps your skin and prevents fine lines and wrinkles</h2>Hydration also helps to combat fine lines and wrinkles. According to Goldenberg, dry skin is more susceptible to damage, which can bring on signs of aging earlier. <a href="https://www.insider.com/how-to-prevent-wrinkles-with-less-money-products-expert-advice-2021-8">Hydrating with a daily moisturizer</a> in the morning and at night after cleaning plumps your skin and prevents signs of aging. If you have oily skin, <a href="https://www.insider.com/best-moisturizer-for-acne-2019-2">moisturizing can also help balance</a> your skin's oil production and reduce acne. <h2>Sometimes, using less is more if your products include wrinkle-fighting ingredients like vitamin C and retinol</h2><div type="image" title="A young man in profile looks in the mirror as he applies skincare product to his face." height="2685" width="3580" msid="88460584" hostid="261"></div>Taking preventative measures to protect your skin doesn't necessarily mean <a href="https://www.insider.com/how-to-prevent-wrinkles-with-less-money-products-expert-advice-2021-8">buying 15 or more expensive products</a>. Experts told Insider it's the quality of your ingredients that matter, not the quantity. "Less is more, your routine doesn't need to be complicated. Trust me, your skin (and wallet) will thank you later!" <a href="https://www.instagram.com/brittaneytrent/?hl=en">licensed aesthetician Brittaney Trent</a> previously told Insider. Instead, including anti-aging products in your routine like retinol and vitamin C can do more for skin. "Retinol is FDA approved for fine lines and wrinkles because it helps improve cellular turnover," <a href="http://www.russakdermatology.com/">Dr. Julie Russak</a>, an NYC-based dermatologist, <a href="https://www.insider.com/bar-soap-toner-on-face-bad-for-acne-scarring-dermatologist-2021-10">previously told Insider</a>. "This treats many skin concerns, including acne and acne scarring as it helps to smooth out the surface of the skin and promote new healthy skin cells."While retinol increases cell turnover, <a href="https://www.insider.com/skincare-products-to-use-to-look-younger-without-botox-surgery-2021-10">vitamin C can lighten hyperpigmentation</a> caused by aging to give the skin a more youthful appearance. It's important to either apply a high SPF sunscreen after using these products or apply them at night before bed, as both vitamin C and retinol can make your skin more sensitive to the sun. <h2>Investing in products that contain EGFs can help your skin regenerate more quickly if retinol is too irritating for you</h2>If you find retinol irritating or drying, <a href="https://www.insider.com/epidermal-growth-factors-why-dermatologists-like-wrinkle-reducer-2021-9">epidermal growth factors (EGFs)</a> are a good substitute. EGFs function similarly to retinols by <a href="https://www.insider.com/skincare-products-to-use-to-look-younger-without-botox-surgery-2021-10">increasing your skin's cell turnover rate.</a> However, they can be less drying and cause less irritation overall for people with sensitive skin. Though serums that contain EGFs typically cost more than your average skincare product, investing in them can be worthwhile for people with sensitive skin who cannot tolerate retinol.

4 of the best wrinkle-fighting tips we learned from dermatologists in 2021

<ul class="summary-list"><li>Dermatologist Dr. Rebecca Baxt said expensive skincare products aren't always worth the money.</li><li>La Mer has a great lip balm but nothing beats a pot of Vaseline, dermatologist, Dr. Mia Jing Gao said.</li></ul>Dermatologists have shared their favorite skincare swaps for luxury products that they say work just as well as the expensive versions. "I'm a huge believer that you don't have to spend a lot of money to get good skincare products," <a href="https://www.cadoganclinic.com/" target="_blank" rel="noopener">Dr. Mia Jing Gao,</a> a consultant <a href="https://www.insider.com/skin-care-products-collagen-supplements-led-mask-toner-avoid-dermatologist-2023-4">dermatologist</a> from London, UK, told Insider.Gao said that in almost every category of <a href="https://www.insider.com/can-i-use-expired-skincare-products-are-they-safe">skincare products</a>, you can find products that are <a href="https://www.insider.com/skincare-products-celebrities-love-under-25-2023-2">good value</a>. Dermatologist Dr. Rebecca Baxt, who is based in New Jersey, agreed that people often spend a lot of money on skincare products but the majority of them are not worth it.Here are the skincare swaps they recommended. <h2>Vaseline and Aquaphor vs La Mer lip balm</h2><div type="image" title="Pot of Vaseline" height="1741" width="2321" msid="99668354" hostid="261"></div>La Mer has a great lip balm but nothing beats a pot of <a href="https://www.insider.com/vaseline-wont-clog-pores-and-can-repair-dry-skin-dermatologist-2021-11">Vaseline</a>, Gao said.And while La Mer lip balm can set you back $75, Vaseline can be as cheap as a couple of bucks.Baxt said Vaseline is a great moisturizer generally, especially for hands, feet, knees and elbows.Gao also recommended Aquaphor Ointment as a lip balm that costs less than $5. She said it has lots of <a href="https://www.insider.com/guides/beauty/best-moisturizer-ingredients">humectants and occlusives</a> in it, which both lock in moisture. Dr. Baxt added that it can be used as a cheap moisturizer too.<h2>The INKEY List vitamin C serum vs SkinCeuticals</h2><div type="image" title="15% Vitamin C + EGF Serum" height="1390" width="1853" msid="99668358" hostid="261"></div><a href="https://www.insider.com/guides/beauty/vitamin-c-for-skin">Vitamin C</a> treatments can brighten your skin and, according to some experts, also reduce the signs of <a href="https://www.insider.com/how-to-prevent-wrinkles-with-less-money-products-expert-advice-2021-8">aging</a>. But they can be pricey because it's difficult to formulate, Gao said. SkinCeuticals' C E Ferulic Vitamin C Antioxidant Serum, for example, is an excellent product, Gao said, but costs $182.However, there are reasonably priced alternatives such as The INKEY List 15% Vitamin C + EGF serum, which at $15.99 costs a tenth of its SkinCeuticals counterpart, Gao said.<h2>CeraVe moisturizer vs Dr. Barbara Sturm</h2><div type="image" title="CeraVe Moisturizing Cream" height="1388" width="1851" msid="99668361" hostid="261"></div>Dr. Barbara Sturm's moisturizing products are popular but expensive, said Gao, with the face cream costing $225.La Mer Moisturizing Cream is also pricey, costing $380 at Sephora for a 60ml pot.Instead, Gao recommended CeraVe Moisturizing Cream that can be picked up at Walmart for under $15, which she said works just as well.Baxt said people unnecessarily spend a lot of money on moisturizer."There are many good brands of creams that are all reasonably priced," she said.She recommends products by Vanicream, CeraVe, and Aveeno as regular-use moisturizers to her patients. <h2>CeraVe cleansers vs Dr. Dennis Gross </h2><div type="image" title="Bottle of CeraVe Hydrating Facial Cleanser" height="1600" width="2133" msid="99668362" hostid="261"></div>You don't have to spend a lot of money on a cleanser either, Gao said.She said to choose a cleanser based on your skin type, but that CeraVe's <a href="https://www.insider.com/best-dermatologist-recommended-skin-cleansers">Hydrating Facial Cleanser</a> and their Blemish Control Cleanser both work well and cost less than $20 a bottle. That is almost half the price of cleansers by Dr. Dennis Gross. Dr. Dennis Gross Alpha Beta AHA/BHA Daily Cleansing Gel is $39 for a 7.5 ounce bottle compared to CeraVe's 12 ounce standard size.Gao said the Dr. Dennis Gross cleanser does a similar job to the CeraVe SA Smoothing Cleanser or the Blemish Control Cleanser. In a previous <a href="https://www.insider.com/best-dermatologist-recommended-skin-cleansers">Insider article</a>, Baxt also recommended CeraVe cleansers.<h2>The Ordinary retinoid vs SkinCeuticals retinol </h2><div type="image" title="The Ordinary Granactive Retinoid 2% Emulsion" height="3900" width="5200" msid="99668364" hostid="261"></div>Gao said that anti-aging retinol products are popular, including SkinCeuticals' $78 Retinol 0.3 Face Cream that she has found works well. But for those on a tighter budget, The Ordinary has a retinol product — Granactive Retinoid 2% Emulsion — that is less potent but still works, Gao said. And it only costs $11.70.

5 cheap versions of expensive skincare products that work just as well, according to dermatologists

<ul><li>In our last feature from the series where we crystal-gazed into 2022 and brought to you some key trends that will impact the industry, we speak to experts from the Indian <keyword id="6357332" type="General" weightage="20" keywordseo="gaming" source="Orion">gaming</keyword> industry.</li><li>They share their thoughts of a few big trends that will dominate the industry in 2022.</li></ul>As we enter 2022, we can only look back and wonder at the meteoric rise online gaming has seen in India in the past two years. While gaming had been witnessing growth, albeit a relatively slow one, before the lockdown, it was during the locked-at-home phase that many across the country not only discovered the joys of gaming, but also realised they could make a healthy living out of it. If most reports coming out in the last one year are to be believed, India will see an even faster growth for the industry in the next few years, and now Bharat is joining in this growth. A recent report by <keyword id="7087972" type="General" weightage="20" keywordseo="mobile-premier-league" source="Orion">Mobile Premier League</keyword> (MPL), an <keyword id="2440542" type="General" weightage="20" keywordseo="esports" source="Orion">esports</keyword> and skill gaming platform revealed that India’s tier-III cities and towns have witnessed a significant rise in the number of online gamers in 2021. The top 30 of them reported up to 170% more gamers compared to 2020. Some of the small towns have more than 100% to up to 200% growth in online gamers. Another report by Sequoia India and BCG said that while the gaming industry in India is currently smaller than that of the US and China and is 1% of the global gaming market, it is generating $1.5B revenue and is expected to triple to over $5 billion by 2025 on the back of the ‘mobile first’ phenomenon. This massive growth has also led to a new breed of influencers who are being followed by hundreds of thousands of engaged audiences. YouTube’s recently released list of top Indian creators on its platform featured 5 gamers. And things are just about starting to get heated. To understand where this highly dynamic industry is headed in this next year, we reached out to a few prominent voices from the industry and this is what they had to say: Lokesh Suji, Director, Esports Federation of India &amp; Vice President of the Asian Esports Federation (AESF) India was a sleeping giant till Covid-19 happened, and now we have established ourselves as a market that cannot be ignored; Stakeholders like the brands, investors, authorities and so on, were just sitting on the fence and observing. But with a market of at least 450 million online gamers, the potential of video games and esports cannot be ignored. The year 2021, has been the inflection point for video games in India. While esports evolves itself into various business models, Non-fungible token (NFT) will be one big trend to watch out for in 2022. Video Games is the best use case for NFTs, customization of the skins, virtual avatars, in-game items/rewards etc. all this already exists in video games (so-called metaverse) and is now starting to be converted into NFTs. One of the key drivers for the meteoric growth of Video Games has been live streaming and esports, and such content creators and/IP holders will eventually look at converting the best of gameplays/streaks/moments into NFTs, which not only help increase monetization for content creators, video game developers etc. but also be a catalyst in terms of retention of fans and users respectively. Anirudh Pandita, Founder, <keyword id="820765" type="General" weightage="20" keywordseo="Loco" source="Orion">Loco</keyword> Gaming has now arrived as a truly mainstream entertainment experience and has become the primary source of entertainment for India’s young generation. 2021 saw the rise of esports and game streaming, and 2022 will see this multiply. In 2021, we saw the arrival of BGMI which all Indian fans were waiting for and in 2022, we will see multiple big publishers release games for India. In 2021, we saw esports go to new heights and we will see continued growth in the sector in the next year as prize money as well as number of games will increase. Game streaming saw the entry of hundreds of thousands of new streamers and millions of viewers, and this trend should accelerate in 2022, with individual streams rivaling those of major traditional sports. Lastly, with blockchain providing interesting use cases, we expect to see interesting new use cases come out to help creators and consumers. We, at Loco, have always aimed at paving the way for gaming to go from a niche hobby to a mainstream national interest- which the year 2021 has helped realize. We are confident that with this, India will cement its place on the global gaming map in 2022. Abhishek Aggarwal, Co-Founder &amp; CEO, <keyword id="12415204" type="General" weightage="20" keywordseo="trinity-gaming" source="Orion">Trinity Gaming</keyword> The gaming industry is progressing, taking complete advantage of the latest developments in technology, software, better internet services, gadgets, cloud technology and more. In the Indian scenario, there is an explosive growth of gamers in this booming industry with creative and engaging content being an important aspect of the system. With more games introduced and with more people joining the pool, more brands are shifting their focus on marketing their brands through these young creators who have an enormous fan following across the age group of 15-30 which is the most targeted audience in advertising terms for both endemic and non-endemic brands. Gaming content has begun to penetrate the Tier II, Tier III locations, and beyond, giving vernacular content creators a chance to grow. With Hindi &amp; Tamil being the two most popular languages in streaming in India, it will surely gain more prominence in the coming time. More people will watch game streaming. Audiences tend to admire their creators and feel more connected to them due to their high level of engagement. The future of gaming beholds a lot and a stronger and classified gaming ecosystem is on the rise. Tarun Gupta, Founder, <keyword id="10820861" type="General" weightage="20" keywordseo="ultimate-battle" source="Orion">Ultimate Battle</keyword> Games and gaming content are highly engaging and we're seeing a huge spike in average and concurrent viewership for gaming content. The consumers are very dynamic and their attention span size has decreased noticeably in GenZ. We see short gaming video content to witness a never seen before hype in the gaming community. The mobile gaming market is expanding in tier 2 and tier 3 cities and we'll witness a rise in engagement in games, viewership, and content creation. Young gamers will play engaging games, consume fast-paced engaging content, and want to socialize with gamers often simultaneously. This will lead to more virtual world socialization among the young generation and higher consumption of gaming content. As such, 2022 will usher higher inclination by brands into the gaming industry to target the young age group of 18 to 25. With many startups and organizations focusing on gaming and esports, we'll see a spike in Esports events and team IPs being created. This will boost the gaming ecosystem in India and open multiple opportunities in careers for gamers and IT professionals. Roland Landers, CEO, <keyword id="3634002" type="General" weightage="20" keywordseo="All-India-Gaming-Federation" source="Orion">All India Gaming Federation</keyword> The Indian gaming industry along with the M&amp;E segment has now become one of the fastest growing sectors in India with around 7.3 Bn downloads in recent years. It has emerged as an important avenue due to a multitude of favorable factors such as young and tech-savvy population, affordable availability of feature-packed smartphones, better internet connectivity, and an overall technological development. The move has also accelerated the growth of multi gaming format in the online gaming space. The Indian gaming industry is expected to reach 3 billion by 2025 and is now projected to grow faster than the global online gaming segment. The industry currently employs 40,000 people in direct jobs and by 2024 the online skill gaming industry is expected to employ around 2 lakh people. This growth will further lead to revenue generation for the country, driven by ease of payment, better security and instant withdrawal of winnings etc. As the regulatory landscape is also evolving and positive judgments are expected from many states, we as an industry leader look forward to an exciting year for this sunrise sector. With its exponential growth, the gaming industry will also attract international investors to invest in the Indian market. Sameer Barde, CEO - E Gaming Federation <div type="image" title="IMG-20220110-WA0005" msid="88826278" hostid="261"></div> Online gaming will become increasingly mainstream and find acceptance as a source of entertainment in 2022. This year, we anticipate a growth rate of over 35 % for the sector as a whole. However, for this to happen, we hope to see government stakeholders accepting the need for regulation to protect the player and industry interests. Increasing monetization and adoption of new-age technology including blockchain and NFTs in the gaming ecosystem will be seen. We expect a larger number of players moving from free-to-play to paying-to-play, in-game purchases, and skill gaming. Industry players will develop new and exciting games for users based on traditional games and Indian themes, keeping the PM’s vision in mind. Additionally, e-Sports being a medal sport in the forthcoming Asian Games in September will result in a significant increase both in terms of acceptance and interest. All in all, we at EGF are excited and believe that this will be a bellwether year for the entire industry. Bhavin Pandya, CEO and Co-Founder, <keyword id="8913431" type="General" weightage="20" keywordseo="Games24x7" source="Orion">Games24x7</keyword> The Indian online skill gaming industry is poised for tremendous growth. With the right support particularly in the form of progressive policy structures, gaming can spur a second software revolution in India. As of today, this industry offers direct employment to almost 50,000 people. It is also a major source of taxation for the exchequer. In addition, the sector has multiplier benefits for several other domains including fintech, banking, semiconductors, animation, and other aspects of Information Technology. The sector has witnessed significant investments from marquee international investors and accounts of several Unicorns. With the right encouragement and support, India can emerge as a global pioneer in gaming technology. Ankur Singh, CEO and Founder, Witzeal We believe that the gaming sector will continue to expand with the high end adoption of AI and data science to understand and provide users experiences they wish for. Future of gaming will likely be based upon newer technologies like Blockchain and its active usage would prove fruitful in the years to come. Another key trend to look forward to is the penetration of gaming in rural areas because the penetration of internet and smartphones is on a gradual rise. Yashash Agarwal, Co-Founder and CEO, <keyword id="3212361" type="General" weightage="20" keywordseo="Gamezop" source="Orion">Gamezop</keyword> <div type="image" title="RIC_8498" msid="88758667" hostid="261"></div> Blockchain gaming is shaping up to be a very interesting space. We are already seeing very interesting games emerge with blockchain and NFTs at the heart of all the action. Games like Axie Infinity have popularized the Play to Earn mechanic and they have been able to scale engagement as well as monetization to huge numbers. Take it one step further and we see that decentralization is fundamentally changing how companies operate: all the way from raising money, to day-to-day governance. This is most notable in DAOs (Decentralized Autonomous Organisations), which follow a bottom-up, community-driven management style. We are excited to see the blockchain gaming projects that emerge from India! Vaibhav Odhekar, COO &amp; Co-Founder, <keyword id="2734866" type="General" weightage="20" keywordseo="POKKT" source="Orion">POKKT</keyword> The gaming industry is constantly evolving, and its popularity will continue to rise. In the last three years, the sector has welcomed 500 million new gamers globally. New technological breakthroughs such as virtual reality have provided another dimension towards entertainment in this domain. For many young folks, the industry has also become a viable career option. Talking about the trends- The audience will continue to diversify in the coming years. So, instead of a male/female audience bias, we'll have a nearly 50-50 gender split, with a lot more older people joining the online gaming space. India is expected to create more global content. Although the percentage is extremely low right now, as more high-quality content is created in India, the trend will improve. Also, e-Sports as a category will grow in popularity. In 2022, there will be a significant increase in the number of movies released worldwide. So, the biggest trend we anticipate to see is a lot more games based on movie franchises. Gaming has its own history of adapting films and gamers are enthralled by such games. Video games are a vast medium that covers a wide variety of genres and experiences that can only be experienced in games, along with contributions from a population from all over the world. Even while many modern games are inspired by movies, they are nevertheless unique in their own way and we expect them to expand in the coming years.

Gaming: What to expect from the Indian gaming and e-sports industry in 2022

<ul class="summary-list"><li>Bird's nest is a delicacy found in Chinese-speaking countries across Asia.</li><li>It's made from the hardened saliva of a swiftlet and can fetch up to S$3,500 ($2,600 USD) per kilogram.</li><li>Swiftlet farms have sprung up to meet customer demand - but they're not without controversy.</li></ul>Who would have thought that a nest made out of hardened bird spit would be a delicacy, a skincare product, and a popular gift across Chinese-speaking countries in Asia? The delicacy is called bird's nest, and it's made from the nest of a swiftlet. The cream-colored translucent orb of solidified saliva looks like the rib cage of a large animal or a mineralized spider web.Edible-nest swiftlets, which can only be found in Southeast Asia and East Asia, do not use twigs for their nest; instead, they produce nests entirely from their own saliva. These nests are edible and are valued for their nutritional benefits. They also feature prominently in Lunar New Year festivities every January and February.Today, you can find the age-old Chinese delicacy in bubble tea, in gas stations, and even at your local 7-11. It's been known to retail for prices from S$8.50-$100 ($6-$75 USD) per bottle depending on the grade and amount of bird's nest as well as whether other ingredients, such as collagen, ginseng, wolfberries (goji berries), are added.<h2>An origin story steeped in myth and legend</h2>For hundreds of years, Chinese communities across China, Taiwan, Hong Kong, and <keyword id="6356662" type="UNKNOWN" weightage="60" keywordseo="singapore">Singapore</keyword> have boiled and ingested these edible birds' nests particularly at old age, when ill or pregnant, or when seeking a bit of that lively facial glow.Even so, the origin story behind bird's nest isn't totally clear."I do not think anyone definitively knows how and why someone ever tried boiling and eating these bird's nests," said Justin Chiam, one of the cofounders of The Purest Co, a Singapore-based bird's nest production company. Founded in late 2019, The Purest Co harvests, processes, cooks, and delivers birds' nests from farms in <keyword id="8692" type="COUNTRY" weightage="60" keywordseo="Indonesia">Indonesia</keyword> direct to consumers in Singapore.One legend has it that Chinese royals, obsessed with maintaining everlasting youth, sent expeditions to different parts of the world and discovered this bird's nest in Indonesia. Another story has it that a general, stranded on an island in Southeast Asia with his troops and only swiftlet nests around, decided to boil and eat the nests, and found his crew to have improved vigor after.<h2>Farming swiftlet nests</h2>Chiam and his cofounder, Stuart Ho, learned about edible bird's nest production from Chiam's uncle, who operates swiftlet houses in Sitiawan, <keyword id="8695" type="COUNTRY" weightage="60" keywordseo="Malaysia">Malaysia</keyword>.In the wild, swiftlet nests are found deep in caves. Swiftlet farmers have to build scaffolding to scale dark, damp walls to obtain their harvest. As demand for the delicacy grew, house nests - multi-storey, concrete, blank, windowless buildings - were built to create an ideal environment for swiftlets to breed. In Malaysia alone, an <a href="https://journals.sagepub.com/doi/10.1177/1474474016684128">estimated</a> 30,000 swiftlet houses contribute US$400 million to the national economy.<div type="image" title="swiftlet house farming birds nest" height="2677" width="3570" msid="81508973" hostid="261"></div>Small birds at the bottom of the <keyword id="6181" type="COMPANY" weightage="60" keywordseo="Food">food</keyword> chain, swiftlets seek out safety and protection from predators such as owls and eagles; they are drawn to house nests because they offer holes small enough to let the swiftlets come and go while deterring larger animals. House nests are built in areas with ample food supply for the swiftlets (such as insects) and kept dark and moist to replicate the natural environment of the cave.Harry Mranata, Managing Director of Pristine Farm, a Singapore-based company with farms in Indonesia, told Insider farms will play baby swiftlet sounds to attract a cohort of "pioneers" to breed in their building. Over time, their friends join them, and the community grows.Mranata said that the birds cannot be kept in captivity, and it is important for them to look for food by themselves: "We cannot feed them, only provide facilities."<div type="image" title="birds nest cave" height="1920" width="2560" msid="81508975" hostid="261"></div><h2>A delicacy with a price tag</h2>The peripatetic life of a swiftlet home is among the reasons why swiftlet nests are so expensive.Mranata said his swiftlet houses have a lifespan of about 10-15 years in which they are financially productive. When an area develops and roads are built, swiftlets start to vacate the farm. At this point, a new farm building has to be constructed in a new area to restart the farming process.The swiftlets in his farms in Indonesia produce nests three or four times a year in the suburbs or areas close to the city, whereas they produce nests about 10 times a year in what he calls "pristine" areas, far from traffic and urbanization. The nests are harvested by measuring their size and monitoring changes in color.White swiftlet nests retail for S$3,500 ($2,600 USD) per kilogram, while "blood nests" - red swiftlet nests - can command up to S$10,000 ($7,400 USD) per kilogram. The red coloration is caused by minerals in the swiftlet nests interacting with the environment. Blood bird's nest is rarely sold in restaurants or packaged in bottles; it is most commonly sold raw and as full cups and pieces for customers to boil at home. Cooking one bowl of bird's nest using nine grams of red swiftlet nest would cost you about S$90-S$110 ($66-$80 USD).The labor-intensive and mechanization-defying process of harvesting nests also accounts for the price of the final product. Farmers have to scale ladders to obtain their harvest, removing each nest gently from the ceilings and ledges where the birds have built homes. They then have to clean the nests and remove any feathers and dirt before cooking them.Cleaning the nests is an intricate process that has to be done with care to preserve the look of the nest. The cleaner the swiftlet nest, the higher the price it can command. Most prized is a "full cup" of nest, which has a higher retail value than the fragments and edges, even though both have the same nutritional value. <div type="image" title="swiftlet birds nest delicacy" height="2448" width="3264" msid="81508977" hostid="261"></div><h2>The appeal of edible bird's nest</h2>Swiftlet nests' immune-boosting properties were once a product of Chinese myth. In recent years, swiftlet farmers and food scientists have been investing in research to prove the nests' nutritional benefits.In edible bird's nests, Malaysian researchers have <a href="https://www.frontiersin.org/articles/10.3389/fphar.2019.01624/full">found high levels of sialic acid</a>, which is also found in breast milk. In 2006, <a href="https://pubmed.ncbi.nlm.nih.gov/16581142/">researchers from Japan</a> demonstrated that bird's nest contains antiviral properties and inhibits infections from influenza; this was <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216576/">later confirmed</a> in 2017 by a team of researchers from Malaysia and California.Research by Hong Kong scientists from 1987 found that<a href="https://pubmed.ncbi.nlm.nih.gov/3497769/"> swiftlet nests contain a compound that acts similarly to Epidermal Growth Factor (EGF)</a>, the glycoprotein known for its anti-aging properties. Swiftlet nests are packaged into essences, used in cosmetics, skincare products, made into pills, and even mixed into coffee. Purest offers a bottled subscription, targeting young consumers who want a daily dose of swiftlet spit vitality while keeping aging at bay. Subscriptions cost between S$209-$359 ($155-$266 USD) per month for a box of four bottles. Many bird's nest brands are also certified halal, and so can be marketed to the Muslim populations in Indonesia, Malaysia and Singapore.<h2>Controversy within the swiftlet-farming industry</h2>Compared to other traditional Chinese medicines such as rhino horn or shark's fin, the bird's nest is "relatively ethical," said Chiam, given that birds do not need to be killed when their nests are harvested.<div type="image" title="freshly harvest birds nest swiftlet" height="2400" width="3199" msid="81508980" hostid="261"></div>When asked if it harms the bird that their nests are taken away, Mranata said swiftlets leave the building in the daytime to hunt for food. It is at this time that swiftlet farmers enter the building to measure, identify, and remove the mature nests. There are no babies in the nest. When a swiftlet returns, "at first they might panic," he said. "They may fly away but then they come back. They are protected by the farm.""After a while, they don't panic anymore. They get used to it," Mranata said.Still, there are accounts of birds being harmed or dying in the process. Environmentalist and attorney Jagath Gunawardana <a href="http://www.sundayobserver.lk/2017/11/05/features/cruelty-served-dish">said in the Sunday Observer</a> that swiftlet farmers do not wait until a chick vacates a nest before harvesting them. Rather, because the farmers prefer for nests to be as fresh as possible, they sometimes collect the nests and throw any eggs and chicks onto the floor. Because swiftlets cannot perch on the ground, these chicks get eaten alive by armies of ants that are attracted to the chicks and broken eggs. In Sarawak, Malaysia's largest state, there have been reports of nest theft <a href="https://time.com/4160913/china-edible-birds-nests-malaysia-indonesia-asia/">depleting an entire swiftlet population</a> of about four million birds in Niah National Park. And in China, a <a href="https://www.asiaone.com/health/red-flag-raised-over-fake-birds-nest">nation-wide check was conducted</a> on all edible bird's nests on the market after tests by the Zhejiang Administration for Industry and Commerce found more than 30,000 cups of red bird's nest to contain up to 350 times the acceptable nitrate levels according to China's health standards.

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