Best printers for Home

Best Mixer Grinder

Best wired Earphones

Best 43 Inch TV in India

Best Wi Fi Routers

Best Home Theatre in India

Smart Watch under 5000

Best Laptops for Education

Best Laptop for Students

A US woman has reportedly been cured of <keyword id="6363554" type="General" weightage="20" keywordseo="HIV" source="Orion">HIV</keyword> disease after undergoing <keyword id="72919" type="General" weightage="20" keywordseo="stem-cell-transplant" source="Orion">stem cell transplant</keyword>. The woman dubbed as the New York patient is also the third person in the world to be cured of HIV disease, after receiving a stem cell transplant. She is in remission after receiving a new combination of specialised stem cell transplants for treatment of acute myeloid leukemia (AML), according to researchers at the <keyword id="94240" type="General" weightage="20" keywordseo="university-of-california-los-angeles" source="Orion">University of California, Los Angeles</keyword>. Despite the cessation of antiretroviral therapy (ART), she has had no detectable levels of HIV for 14 months, they said. "This woman has been in remission of AML for four and a half years and has had no HIV rebound in the 14 months since antiretroviral therapy was stopped," said <keyword id="13194015" type="General" weightage="20" keywordseo="dr-yvonne-bryson" source="Orion">Dr Yvonne Bryson</keyword>, Professor and specialist in pediatric infectious diseases and HIV pathogenesis at the <keyword id="1406743" type="General" weightage="20" keywordseo="david-geffen-school-of-medicine" source="Orion">David Geffen School of Medicine</keyword> at UCLA. "If HIV remission continues and she is determined to be cured, she would be only the third person to achieve cure and the first HIV remission to have been successfully engrafted with umbilical cord blood cells with a mutation that is protective against HIV-1 combined with stem cells from an adult, haploidentical ("half-matched") related donor," <keyword id="3931880" type="General" weightage="20" keywordseo="bryson" source="Orion">Bryson</keyword> said. The two previous patients with HIV cure received adult donor cells - one from bone marrow and one from blood stem cells - that had the protective mutation, but no umbilical cord blood cells. The woman is of mixed race who was diagnosed with acute HIV in 2013 and high-risk AML in 2017. She achieved leukemia remission after chemotherapy. Prior to receiving the stem cell transplant, the participant's HIV was well-controlled but detectable. In 2017, she received a transplant of cord blood stem cells supplemented with adult donor cells from a relative (called haplo cells). After receiving the stem cell transplant, she engrafted with 100 per cent cord blood cells at day 100 and had no detectable HIV. At 37 months post-transplant, the patient stopped taking ART. According to the study team, no HIV was detected in the participant for 14 months except for a transient detection of trace levels of HIV DNA in the woman's blood cells at 14 weeks after stopping ART. The haplo cells only transiently engrafted and contributed to rapid recovery. HIV remission resulting from a stem cell transplant had been previously observed in two cases. The first, known as the "Berlin patient" (a Caucasian male), experienced HIV remission for 12 years and was deemed cured of HIV; he died of leukemia in September 2020. The "London patient" (a Latino male) has been in HIV remission for more than 30 months. Although stem cell transplantation is not a therapy for HIV, its effects in patients living with HIV and undergoing therapy for blood or lymph cancers provide researchers with insights and potential targets in HIV treatment. "This study provides hope for the use of cord blood cells or a combination of cord blood cells and haploidentical (half-matched) grafts to achieve HIV-1 remission for individuals requiring transplantation for other diseases. It also provides proof that HIV-1 viral 'reservoirs' can be cleared sufficiently to afford remission and possibly cure in the setting of resistant target cells," said Bryson. SEE ALSO: <a target="_blank" class="c-link c-message_attachment__title_link" href="https://www.businessinsider.in/tech/mobile/news/oneplus-nord-ce-2-5g-oneplus-tv-y1s-y1s-edge-to-launch-in-india-today-heres-how-to-catch-the-livestream/articleshow/89636431.cms">OnePlus Nord CE 2 5G, OnePlus TV Y1S &amp; Y1S Edge to launch in India today – here’s how to catch the livestream</a> <a target="_blank" class="c-link c-message_attachment__title_link" href="https://www.businessinsider.in/tech/mobile/news/samsung-galaxy-s22-series-mobile-launched-in-india-check-out-price-and-specification/articleshow/89637809.cms">Samsung Galaxy S22, S22+ and S22 Ultra launched in India – price, launch offers, availability and everything else you need to know</a>

An American woman gets reportedly cured of HIV after stem cell transplant

<ul class="summary-list"><li>A woman is still free of HIV 5 years after receiving a stem cell transplant, researchers say.</li><li>The woman continued to show undetectable viral levels months after stopping her HIV medication.</li></ul>A woman who received a stem cell transplant to treat her cancer has also been "cured" of HIV five years after receiving the treatment, and even after stopping her <a href="https://www.insider.com/guides/health/sex-relationships/stages-of-hiv">HIV</a> medication, researchers say.The woman, known as the "New York Patient," needed a stem cell transplant after doctors diagnosed her with acute leukemia, according to a <a href="https://www.cell.com/cell/fulltext/S0092-8674(23)00173-3#secsectitle0030" target="_blank" rel="noopener">report</a> published in the scientific journal, Cell. Nearly five years post-transplant, the woman also showed "undetectable HIV RNA levels," according to the report.The report comes a month after another group of researchers said a man in Germany was <a href="https://www.insider.com/hiv-third-confirmed-case-cure-stem-cell-transplant-2023-2">"cured"</a> of HIV after receiving a bone marrow transplant 10 years earlier to treat his leukemia. Having an undetectable HIV viral load keeps the disease from affecting a person's health and "prevents transmission to others through sex or syringe sharing, and from mother to child during pregnancy, birth, and breastfeeding," according to the <a href="https://www.cdc.gov/hiv/risk/art/index.html" target="_blank" rel="noopener">CDC</a>.The woman decided to stop taking her <a href="https://www.insider.com/hiv-medication-soon-come-in-strawberry-flavored-form-for-kids-2020-12">HIV medication</a> 30 months after her transplant to see if she could possibly be "cured" of the virus, the report says. Her initial break from the medication lasted only 13 days after a surge in the COVID-19 pandemic forced her back on the medication, according to the researchers.The report says she then stopped taking the medication again at 37 weeks post-transplant and found that her virus levels had remained undetectable through 18 months, "heralding HIV-1 remission and a possible HIV-1 cure.""We're calling this a possible cure rather than a definitive cure — basically waiting on a longer period of follow up," Dr. Yvonne Bryson, director of the Los Angeles-Brazil AIDS Consortium at UCLA and one of the doctors who oversaw the case, said during a news conference on Wednesday, according to <a href="https://www.livescience.com/1st-woman-given-stem-cell-transplant-to-cure-hiv-is-still-virus-free-5-years-later" target="_blank" rel="noopener">LifeScience</a>.Scientists prefer to refer to HIV patients as "in long-term remission" rather than cured because it's still unclear how permanent the results of long-term HIV remission will be, Insider previously <a href="https://www.insider.com/hiv-cures-cancer-treatment-natural-control-2022-8">reported</a>.Deborah Persaud, interim director of pediatric infectious diseases, a professor of pediatrics at Johns Hopkins University School of Medicine, and co-lead author of the woman's case report, told <a href="https://www.healthline.com/health-news/breakthrough-treatment-cured-first-woman-of-hiv#Could-her-HIV-return?-" target="_blank" rel="noopener">HealthLine</a> that the longer the woman is able to stay cancer free, the more likely it is that her HIV viral load will not return to a point where it is dangerous."The longer she goes without rebound the more likely it is that the virus won't return in her blood to detectable viral load levels with our standard clinical assays," Persaud said.

A woman remains free of HIV 5 years after receiving a stem cell transplant, researchers say

You Searched For "dr yvonne bryson" and got 2 results

An American woman gets reportedly cured of HIV after stem cell transplant

IANS

A woman remains free of HIV 5 years after receiving a stem cell transplant, researchers say

Kenneth Niemeyer

Popular Keywords

Buying Guides