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<ul><li>Personal data of thousands of Indians has reportedly been leaked from the CoWIN portal.</li><li>According to a report, details such as name, ID proof, gender and more have been leaked.</li><li>The data has been spotted on <keyword id="1275203" type="General" weightage="100" keywordseo="telegram" source="Orion">Telegram</keyword> and a bot sends the data when you send the user’s phone number.</li></ul>In what could be a major data breach, personal information of people who received the Covid-19 vaccine has reportedly been leaked online. This data includes the user’s name, date of birth, gender, and their ID. According to a report by Malayala Manorama, the data has been leaked through the CoWIN portal that was designed to help citizens book their vaccine slots. As per the report, all you need to do is enter the phone number of a person who has received the Covid-19 vaccine on a Telegram bot and it will fetch important details about the user. This, as per the report, has put important data such as Aadhaar, PAN, voter ID and passport of thousands of users at risk. The government has not revealed anything about the leak yet. <div type="twitter" handle="SaketGokhale" handlename="SaketGokhale" favoritecount="0" retweetcount="0" id="1668104757704269824"></div> Trinamool Congress (TMC) spokesperson Saket Gokhale has <a href="https://twitter.com/SaketGokhale/status/1668104757704269824">shared</a> screenshots of the Telegram bot, with vaccination information of people like P Chidambaram, Jairam Ramesh and Derek O Brien. <cmsannotation type="cmsannotation" annotationid="Not the first Covid-19 related data leak" comment="subhead" text="Not the first Covid-19 related data leak">Not the first Covid-19 related data leak</cmsannotation> This is not the first time that CoWIN data has come under the scanner. In 2022, data of over 20,000 people, including their name, mobile number, Covid-19 test result and their address was<a href="https://www.hindustantimes.com/india-news/data-meant-for-cowin-portal-leaked-online-over-20-000-indians-likely-affected-101642767559692.html"> reportedly</a> leaked. This data was meant to be uploaded on the CoWIN platform. In another instance, data of over 15 crore citizens was<a href="https://www.timesnownews.com/technology-science/article/cowin-apps-covid-19-vaccination-data-of-15-crore-users-leaked-and-up-for-sale-government-denies-breach/769434"> reportedly</a> leaked in 2021 and the hackers put the data on sale. The government however refuted the claim and said that the CoWIN platform was never hacked. SEE ALSO: <a href="https://www.businessinsider.in/tech/news/vision-pro-to-ios-17-apples-top-six-announcements-at-wwdc-2023/articleshow/100786632.cms">Vision Pro to iOS 17: Apple’s top six announcements at WWDC 2023</a> <a href="https://www.businessinsider.in/finance/news/2000-note-withdrawal-how-to-exchange-notes-is-it-a-legal-tender-and-other-questions-answered/articleshow/100412941.cms">₹2,000 note withdrawal – How to exchange them, is it a legal tender and other questions answered</a> <a href="https://www.businessinsider.in/tech/news/apple-app-store-prevented-over-2-billion-in-fraudulent-transactions-last-year-banned-282-million-user-accounts/articleshow/100322718.cms">Apple App Store prevented over $2 billion in fraudulent transactions last year, banned 282 million user accounts</a>

Covid-19 vaccination data reportedly leaked – ID proof, date of birth and other details available on Telegram

The <keyword id="22407175" type="General" weightage="100" keywordseo="U-WIN" source="keywords">U-WIN</keyword> portal, a replication of the <keyword id="19897423" type="General" weightage="20" keywordseo="COVID-19" source="keywords">Covid-19</keyword> vaccine management system Co-WIN, is set for a pan-India launch likely by the end of August, aiming to maintain an electronic registry of routine immunisations, official sources said. Currently, U-WIN is in pilot mode across all states and Union Territories, except for West Bengal, which is yet to start uploading data, the sources told PTI, adding that it is still under consideration in the state. The U-WIN platform captures every <keyword id="19933690" type="General" weightage="20" keywordseo="vaccination" source="keywords">vaccination</keyword> event for pregnant women and children under the Universal Immunization Programme (UIP). Minister of Finance <keyword id="19916618" type="General" weightage="20" keywordseo="nirmala-sitharaman" source="keywords">Nirmala Sitharaman</keyword> had announced in the interim Budget for 2024-2025 that U-WIN, along with intensified efforts under Mission Indradhanush, will be rolled out nationwide for managing <keyword id="21423640" type="General" weightage="20" keywordseo="immunisation" source="keywords">immunisation</keyword>. "The U-WIN will ensure timely administration of vaccine doses by digitally recording every vaccination event under the Universal Immunisation Programme among all pregnant women and children aged 0-5 years," an official told PTI. "The portal will target 2.9 crore pregnant women and 2.6 crore infants (0-1 years) annually by providing 11 vaccines against 12 vaccine preventable diseases -- diphtheria, measles, rubella, and tetanus through more than 1.2 crore vaccination sessions across the country," the official added. The platform generates a uniform QR-based, digitally verifiable e-vaccination certificate, similar to Covid vaccination certificate, which can be accessed anytime by the citizens through a single click. Vaccination records under UIP are being maintained manually as of now. So this will do away with the hassle of keeping a physical record, the officials explained. It will enable the digitisation of session planning, and updating vaccination status on a real-time basis, they added. "Also, there is no mechanism of individual tracking. There is also lack of awareness among beneficiaries about session location and date especially in urban areas and iniquity in immunisation coverage in states and UTs," another official said. "Besides, another major issue is that immunisation at private health facilities is not recorded," the official added. The U-WIN is going to be the single source of information for immunisation services which will record pregnancy details and outcome, newborn registration and immunisation at birth. It will update vaccination status, and delivery outcome, among others, on real time, the official said. As of July 9, 2024, the pilot has registered 5.33 crore beneficiaries on U-WIN. Over 83.55 lakh vaccination sessions have been digitally conducted, and 18.15 crore vaccine doses have been recorded. The platform aims to reduce zero-dose and left-out children through a name-based tracking mechanism and empower citizens with anytime, anywhere access to vaccination services, particularly benefiting migratory populations, the official said. "The U-WIN portal is likely to be launched pan <keyword id="19895063" type="General" weightage="20" keywordseo="India" source="keywords">India</keyword> in August end," the official stated. Citizens can self-register for vaccinations via the U-WIN web portal or its Android mobile application, select preferred vaccination centres, and schedule appointments. Automated SMS alerts inform citizens about registration confirmations, administered doses, and upcoming dose reminders, ensuring timely and age-appropriate vaccinations. It also facilitates the creation of Ayushman Bharat Health Account (ABHA) IDs for comprehensive health record maintenance. The U-WIN also supports the frontline workers to digitally record all vaccination events for children and pregnant women for complete, accurate and easy record maintenance, the official said.

Pan-India rollout of U-WIN to track routine immunisations likely by Aug end

The Indian Council of Medical Research Director General Dr Rajiv Bahl on Monday criticised a recently published study on the long-term safety analysis of the <keyword id="9485939" type="General" weightage="100" keywordseo="covaxin" source="Orion">Covaxin</keyword> in adults and adolescents for its poor methodology and design, and clarified the article misleadingly and erroneously "acknowledges" <keyword id="19918794" type="General" weightage="20" keywordseo="ICMR" source="keywords">ICMR</keyword>. Dr Bahl said the study had no control arm of unvaccinated individuals for comparing the rates of events between the vaccinated and unvaccinated groups. Hence, the reported events in the study cannot be linked or attributed to COVID-19 vaccination. He added that the ICMR is not associated with the study and has not provided any financial or technical support for the research. The ICMR DG has written a letter to the authors of the paper and Editor of the journal to immediately remove the acknowledgement to ICMR and publish an erratum. A research paper, titled 'Long-Term Safety Analysis of the BBVl52 <keyword id="21730391" type="General" weightage="20" keywordseo="coronavirus-vaccine" source="keywords">Coronavirus Vaccine</keyword> in Adolescents and Adults: Findings from a l-Year Prospective Study in North India' stated that nearly one-third of the 926 participants in the study who received Bharat Biotech's anti-Covid vaccine Covaxin reported 'adverse events of special interest,' or AESI. Dr Bahl said that ICMR was acknowledged for research support without any prior approval of or intimation to ICMR, which is inappropriate and unacceptable. He stated that ICMR cannot be associated with this poorly designed study which purports to present a "safety analysis" of Covaxin due to several critical flaws. He said the study does not even provide background rates of observed events in the population, making it impossible to assess the change in incidence of observed events in the post-vaccination period. Baseline information of study participants is missing. The study tool used is inconsistent with 'Adverse Events of Special Interest (AESI)' as defined in the reference provided in the paper for AESI. The method of data collection has a high risk of bias, he said. Study participants were contacted telephonically one year after vaccination and their responses were recorded without any confirmation with clinical records or by physician examination, he pointed out. Dr Bahl also noted that similar acknowledgements to ICMR have been made in previous papers without permission, raising concerns about the authors' practices. "The authors have been urged to immediately rectify the acknowledgment to ICMR and publish an erratum. Additionally, they are asked to address the methodological concerns raised. Failure to do so may prompt ICMR to consider legal and administrative action," he said. The Editor has been asked to retract the paper which implicitly makes conclusions on <keyword id="21495684" type="General" weightage="20" keywordseo="vaccine-safety" source="keywords">vaccine safety</keyword> which are not supported by evidence. The study, conducted by researchers from the Banaras Hindu University from January 2022 to August 2023, stated that nearly 50 per cent of 926 study participants in the study complained of infections during the follow-up period, predominated by viral upper respiratory tract infections. Serious AESI, which included stroke and Guillain-Barre syndrome, were reported in one per cent of individuals, the study, which looked at long-term safety of the BBV152 (Covaxin) vaccine in adolescents and adults, claimed. The study involved 635 adolescents and 291 adults, who received the BBV152 vaccine.

BHU study on Covaxin side effects poorly designed, critically flawed: ICMR Director General

The pharmaceutical giant <keyword id="19910149" type="General" weightage="20" keywordseo="AstraZeneca" source="keywords" meta.keywordsubtype="org" meta.entityname="AstraZeneca" meta.hostid="261" meta.entityid="AstraZeneca">AstraZeneca</keyword>'s <keyword id="20040659" type="General" weightage="20" keywordseo="COVID-19-vaccine" source="keywords">COVID-19 vaccine</keyword> is being withdrawn worldwide after the company acknowledged for the first time in court documents that it can cause a rare and dangerous side effect, according to a report in the British Newspaper 'The Telegraph'. AstraZeneca has announced that the <keyword id="19959412" type="General" weightage="20" keywordseo="vaccine" source="keywords">vaccine</keyword> was being removed from markets for commercial reasons. It further said that the vaccine was no longer being made or supplied, having been superseded by updated vaccines that fight new variants. The application to withdraw the vaccine was made on March 5 and came into effect on May 7. The vaccine can be no longer used in the European Union following the company's decision to withdraw its "marketing authorisation." Similar applications will be submitted in the UK and other nations in the coming months that have given a go-ahead to the vaccine, known as Vaxzevria. In recent months, Vaxzevria has come under scrutiny over a very rare side effect, which causes blood clots and low blood platelet counts. In court documents, AstraZeneca in the High Court in February admitted that the vaccine "can, in very rare cases, cause <keyword id="20218859" type="General" weightage="20" keywordseo="TTS" source="keywords">TTS</keyword>". TTS which stands for <keyword id="21475609" type="General" weightage="20" keywordseo="Thrombosis-with-Thrombocytopenia-Syndrome" source="keywords">Thrombosis with Thrombocytopenia Syndrome</keyword> has been associated with at least 81 deaths in the UK and hundreds of serious injuries. More than 50 alleged victims and grieving relatives have filed a lawsuit against AstraZeneca in a High Court case. AstraZeneca has insisted that the decision to withdraw the vaccine is not related to the case or admission that it can cause TTS and termed the timing a pure coincidence, according to The Telegraph report. "We are incredibly proud of the role Vaxzevria played in ending the global pandemic. According to independent estimates, over 6.5 million lives were saved in the first year of use alone and over three billion doses were supplied globally. Our efforts have been recognised by governments around the world and are widely regarded as being a critical component of ending the global pandemic," The Telegraph quoted AstraZeneca as saying. In a statement, the pharmaceutical giant said, "As multiple, variant Covid-19 vaccines have since been developed, there is a surplus of available updated vaccines", adding that it has led to a decline in demand for Vaxzevria, which is no longer being manufactured or supplied, The Telegraph reported. It further announced its decision to initiate the withdrawal of the marketing authorisations for Vaxzevria within Europe. The company said, "We will now work with regulators and our partners to align on a clear path forward to conclude this chapter and significant contribution to the Covid-19 pandemic." Last week, AstraZeneca reiterated its commitment to patient safety while emphasising the vaccine's overall safety profile. An AstraZeneca spokesperson had stated, "Our sympathy goes out to anyone who has lost loved ones or reported health problems. Patient safety is our highest priority, and regulatory authorities have clear and stringent standards to ensure the safe use of all medicines, including vaccines." This comes in the wake of a recent admission by AstraZeneca, the pharmaceutical company, that its <keyword id="19896627" type="General" weightage="20" keywordseo="covid" source="keywords">Covid</keyword> vaccine Covishield and Vaxzevria "can, in very rare cases, cause Thrombosis Thrombocytopenia Syndrome (TTS)." Despite these rare occurrences, the pharmaceutical company maintained that extensive clinical trial data and real-world evidence consistently support the vaccine's safety and efficacy. Regulatory agencies worldwide continue to assert that the benefits of vaccination outweigh the risks of such extremely rare side effects. 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AstraZeneca withdraws COVID-19 vaccine worldwide, cites commercial reasons

Sydney, Aug 15 (The Conversation): The <keyword id="19896311" type="General" weightage="20" keywordseo="World-Health-Organization" source="keywords" meta.keywordsubtype="org" meta.entityname="World Health Organization" meta.hostid="261" meta.entityid="World Health Organization">World Health Organization</keyword> (<keyword id="19895006" type="General" weightage="20" keywordseo="WHO" source="keywords">WHO</keyword>) has declared <keyword id="20965747" type="General" weightage="100" keywordseo="mpox" source="keywords">mpox</keyword> a public health emergency of international concern, after rising cases in the <keyword id="22796094" type="General" weightage="20" keywordseo="Democratic-Republic-of-the-Congo" source="keywords">Democratic Republic of the Congo</keyword> and the potential for further spread. This now triggers a coordinated international response to an extraordinary event and the mobilisation of resources, such as vaccines and diagnostic testing, to curb the spread of this infectious disease. But WHO has not declared mpox a <keyword id="19913581" type="General" weightage="20" keywordseo="pandemic" source="keywords">pandemic</keyword>. Rather, the measures it has triggered are designed to prevent it from becoming one. <h2>What triggered this latest alert?</h2> Mpox, once known as monkeypox, is a viral infection closely related to <keyword id="22362924" type="General" weightage="20" keywordseo="smallpox" source="keywords">smallpox</keyword>. Initial symptoms include a fever, headache, swelling of the lymph nodes and muscle ache. A typical rash follows, mainly on the face, hands and feet. The spread of mpox through certain African countries led the Africa Centres for Disease Control and Prevention to declare earlier this week mpox a public health emergency of continental security. This is the first time the organisation has issued such an alert since it was established in 2017. The situation in the Democratic Republic of the Congo in central Africa has been particularly worrying for more than a year. There are two types or clades of mpox. Clade II, which originates in west Africa, is less severe. It has a fatality rate of up to 1 per cent (in other words, roughly one in 100 are expected to die from it). But clade I, from central Africa, has a fatality rate of up to 10 per cent (up to one in ten die). This compares to a 0.7 per cent fatality rate for the Omicron variant of SARS-CoV-2, the virus that causes COVID. The Democratic Republic of the Congo is seeing large epidemics of the more deadly clade I mpox. Mpox is endemic in some parts of central and west Africa, where the virus exists in animals and can spread to humans. Outbreaks have been increasing, with more human-to-human spread, since 2017. This is partly due to very low levels of immunity to the mpox virus, which is related to the virus that causes smallpox. Mass vaccination against smallpox ceased more than 40 years ago globally, resulting in minimal immunity in populations today against mpox. The WHO designation announced this week relates to the clade I. Not only does this have a higher fatality rate, it has new mutations that enhance spread between people. These changes, and the global lack of immunity to mpox, makes the world's population vulnerable to the virus. <h2>There are two different epidemics</h2> In 2022, an epidemic of mpox swept through non-endemic countries, including beyond Africa. This was a variant of clade II originating from Nigeria, called clade IIb. This was sexually transmitted, predominantly affecting men who have sex with men, and had a low fatality rate. That epidemic peaked in 2022, with vaccines made available to people at risk in high-income countries, but there has been an uptick in 2024. At the same time, large clade I epidemics were occurring in the Democratic Republic of the Congo, but with far less attention. Vaccines were not available there, even in 2023, when there were 14,626 cases and 654 deaths. Mortality was 4.5 per cent, and higher in children. In fact, most cases and deaths in the Democratic Republic of the Congo have been children. This means most transmission there is non-sexual and is likely to have occurred through close contact or respiratory aerosols. However, in 2023 an <keyword id="20877025" type="General" weightage="20" keywordseo="outbreak" source="keywords">outbreak</keyword> in a non-endemic part of the country, South Kivu in the east, appeared to be by sexual transmission, indicating more than one epidemic and different transmission modes in the Democratic Republic of the Congo. By mid-2024, there were already more cases in the country than all of 2023 - more than 15,600 cases and 537 deaths. Testing capacity is low in the Democratic Republic of the Congo, most cases are not confirmed by lab testing, and the data we have are from a small sample of genomic sequences from the Kamituga region of South Kivu. This show mutations to the clade I virus around September 2023, to a variant termed clade Ib, which is more readily transmissible between people. We do not have much data to compare these viruses with the viruses causing cases in the rest of the country. <h2>Mpox is spreading internationally</h2> In the past month, the virus has spread to countries that share a border with the Democratic Republic of the Congo - Rwanda and Burundi. It has also spread to other east African countries, such as Kenya and Uganda. None of these countries have had mpox cases previously. In an interconnected, mobile world, cases may spread to other continents, as mpox did in 2018 from Nigeria to the United Kingdom and other countries. A few travel-related cases between 2018 and 2019 may have led to the large multi-country 2022 clade IIb epidemic. <h2>We have vaccines, but not where they are needed</h2> As the mpox virus and smallpox viruses are related (they are both orthopoxviruses), smallpox vaccines offer protection against mpox. These vaccines were used to control the 2022 clade IIb epidemic. However, most of the world has never been vaccinated, and has no immunity to mpox. The newer <keyword id="19959412" type="General" weightage="20" keywordseo="vaccine" source="keywords">vaccine</keyword> (called Jynneos in some countries and Imvamune or Imvanex in others) is effective. However, supplies are limited, and vaccine is scarce in the Democratic Republic of the Congo. WHO's declaration of mpox as a public health emergency of international concern will help mobilise vaccines to where they are needed. The Africa Centres for Disease Control had already begun negotiations to secure 2,00,000 doses of vaccine, which is a fraction of what is required to control the epidemic in the Democratic Republic of the Congo. <h2>What happens now?</h2> Ultimately, a serious epidemic anywhere in the world is a concern for all of us, as it can spread globally through travel, as we saw with the COVID pandemic. Controlling it at the source is the best measure, and WHO's latest declaration will help mobilise the required resources. Surveillance for spread of this more serious version of mpox is also essential, bearing in mind that many countries do not have the capacity for widespread testing. So we'll have to rely on "suspected cases", based on a clinical definition, to keep track of the epidemic. Open-source epidemic intelligence - such as using AI to monitor trends in rash and fever illness - can also be used as an early warning system in countries with weak health systems or delayed reporting of cases. A further complication is that 20-30 per cent of people with mpox may simultaneously have chickenpox, an unrelated infection that also causes a rash. So an initial diagnosis of chickenpox (which is easier to test for) does not rule out mpox. Effective communication and tackling push-back against public health measures and disinformation is also key. We saw how important this was during the COVID pandemic. Now, WHO will coordinate the global mpox response, focusing on equity in disease prevention and access to diagnostics and vaccines. It is up to individual countries to do their best to comply with the International Health Regulations, and the protocols for how such a global emergency are managed.

WHO has declared mpox a global health emergency. What happens next?

<ul class="summary-list"><li>US stocks nosedived on Thursday after several discouraging economic data points.</li><li>Jobless claims soared past estimates to the highest level seen in nearly a year.</li></ul>US stock indexes saw a deep sell-off on Thursday as a combination of rising unemployment and slowing economic indicators weighed on markets.In the labor market, new data showed jobless claims came in at 249,000 for last week, above estimates of 236,000. That number marks the highest level in nearly a year and is another signal to the Fed that rate cuts are needed soon.Investors are pricing in a 100% chance of Fed rate cuts in September, according to the<a target="_blank" href="https://www.cmegroup.com/markets/interest-rates/cme-fedwatch-tool.html"> CME FedWatch tool</a>. During an FOMC meeting on Wednesday, Fed Chair Jerome Powell suggested the Fed would be "data dependent, but not data-point dependent" in making the decision to cut rates.Meanwhile, new data shows ISM manufacturing slid further into contraction territory in July. The ISM manufacturing index dropped from 48.5% in June to 46.8% in July—an eight-month low—showing that U.S. factories are still in a downturn.Further data shows construction spending unexpectedly declined in June, falling 0.3% to $2.15 trillion. Economists had predicted a 0.2% rise, according to a poll by Reuters.The fall comes as single-family home construction slowed due to higher mortgage rates.The market reaction shows investor optimism over the prospect of a September rate cut — and potentially <a target="_blank" class="" href="https://www.businessinsider.com/us-economy-slowdown-signal-flashed-interest-rate-cuts-accelerate-fed-2024-8">more aggressive cuts</a> than are currently being expected — is being outweighed by negative economic developments.Here's where US indexes stood at the 4 p.m. closing bell on Wednesday:<ul><li><a target="_blank" href="https://markets.businessinsider.com/index/s&amp;p_500?utm_source=markets&amp;utm_medium=ingest%3Futm_source%3Dmarkets&amp;utm_medium=ingest&amp;utm_medium=ingest&amp;utm_source=markets&amp;utm_medium=ingest&amp;utm_source=markets">S&amp;P 500</a>: 5,446.68, down 1.4%</li><li><a target="_blank" href="https://markets.businessinsider.com/index/dow_jones?utm_source=markets&amp;utm_medium=ingest%3Futm_source%3Dmarkets&amp;utm_medium=ingest&amp;utm_medium=ingest&amp;utm_source=markets&amp;utm_medium=ingest&amp;utm_source=markets">Dow Jones Industrial Average</a>: 40,347.97, down 1.2% (495 points)</li><li><a target="_blank" href="https://markets.businessinsider.com/index/nasdaq_composite?utm_source=markets&amp;utm_medium=ingest%3Futm_source%3Dmarkets&amp;utm_medium=ingest&amp;utm_medium=ingest&amp;utm_source=markets&amp;utm_medium=ingest&amp;utm_source=markets">Nasdaq composite</a>: 17,194.14, down 2.3%</li></ul>Here's what else happened today:<ul><li>Moderna's stock<a target="_blank" href="https://markets.businessinsider.com/news/stocks/moderna-stock-price-crash-covid19-shots-european-demand-2024-8"> tumbled as much as 21%</a> after posting a disappointing sales slump as demand for its Covid-19 vaccine slows.</li><li>Jensen Huang just got <a target="_blank" href="https://markets.businessinsider.com/news/stocks/jensen-huang-fortune-soars-after-record-day-nvidia-stock-price-2024-8">$12 billion richer</a> in a single day as Nvidia's stock soared on Wednesday.</li></ul>In commodities, bonds, and crypto:<ul><li><a target="_blank" href="https://markets.businessinsider.com/commodities/oil-price?utm_medium=ingest&amp;utm_source=markets&amp;utm_medium=ingest&amp;utm_source=markets">Brent crude</a>, the international benchmark, fell 0.8% to $80.05 a barrel.</li><li><a target="_blank" href="https://markets.businessinsider.com/commodities/gold-price?utm_medium=ingest&amp;utm_source=markets&amp;utm_medium=ingest&amp;utm_source=markets">Gold</a> rose 0.6% to $2,441.80 per ounce.</li><li><a target="_blank" class="" href="https://markets.businessinsider.com/currencies/btc-usd?utm_medium=ingest&amp;utm_source=markets">Bitcoin</a> slipped 1.9% to $63,324.32.</li></ul>

Stock market today: Indexes tank as data paints a negative picture for the economy

<ul class="summary-list"><li>Florida Surgeon General Joseph Ladapo cut data from a COVID-19 vaccine safety study, per multiple reports.</li><li>Ladapo <a href="https://apnews.com/article/business-university-of-florida-ron-desantis-florida-gainesville-43d2f0f62f44d012546acf46aa96eda8" target="_blank" rel="noopener">was appointed</a> by Florida Gov. Ron DeSantis in 2021 to head the Florida Department of Health.</li></ul>TAMPA, Fla. (AP) — An analysis that was the basis of a highly criticized recommendation from Florida's surgeon general cautioning young men against getting the COVID-19 vaccine omitted information that showed catching the virus could increase the risk of a cardiac-related death much more than getting the mRNA shot, <a href="https://www.tampabay.com/news/health/2023/04/07/florida-surgeon-general-covid-19-vaccine-study-heart-problems-men/?utm_content=%40TB_Tmes&amp;utm_source=twitter&amp;utm_medium=social&amp;utm_campaign=SocialFlow" target="_blank" rel="noopener">according to drafts</a> of the analysis obtained by the Tampa Bay Times.The nonbinding recommendation made by Florida Surgeon General Joseph Ladapo last fall ran counter to the advice provided by the federal Centers for Disease Control and Prevention. Ladapo, a Harvard-trained medical doctor <a href="https://apnews.com/article/business-university-of-florida-ron-desantis-florida-gainesville-43d2f0f62f44d012546acf46aa96eda8" target="_blank" rel="noopener">who was appointed</a> by Florida Gov. Ron DeSantis in 2021 to head the Florida Department of Health, has drawn intense scrutiny over his shared resistance with the Republican governor to COVID-19 mandates for vaccines and masks, and other health policies endorsed by the federal government.The early drafts of the analysis obtained by the Times through a records request showed that catching COVID-19 could increase the chances of a cardiac-related death much more than getting the vaccine, but that information was missing from the final version put out by the Florida Department of Health last October.Ladapo said that the risk of men ages 18 to 39 having cardiac complications outweighed the benefits of getting the mRNA vaccine.Several weeks after <a href="https://www.politico.com/news/2023/04/24/florida-surgeon-general-covid-vaccine-00093510" target="_blank" rel="noopener">the Tampa Bay Times report</a>, <a href="https://www.politico.com/news/2023/04/24/florida-surgeon-general-covid-vaccine-00093510" target="_blank" rel="noopener">Politico</a> published <a href="https://www.politico.com/f/?id=00000187-b36b-d739-a797-f3ef41e30000" target="_blank" rel="noopener">a draft showing Ladapo's notes.</a> The document titled "Dr. L's Edits" shows where the language was changed.Matt Hitchings, an infectious disease epidemiologist and professor of biostatistics at the University of Florida, told the Times that it seems that sections of the analysis were omitted because they did not fit the narrative the surgeon general wanted to push."This is a grave violation of research integrity," Hitchings said. "(The vaccine) has done a lot to advance the health of people of Florida and he's encouraging people to mistrust it."In a statement on Twitter posted Saturday in response to the Times' story, Ladapo said, "It's not only unfortunate that COVID has corrupted scientists' ability to think clearly about epidemiology but also sad that people rush to defend a vaccine that has shown increased cardiovascular risk in multiple studies."In a statement to Politico Ladapo said: "To say that I 'removed an analysis' for a particular outcome is an implicit denial of the fact that the public has been the recipient of biased data and interpretations since the beginning of the mRNA COVID-19 vaccine campaign. I have never been afraid of disagreement with peers or media."Last year, Ladapo <a href="https://apnews.com/article/covid-health-florida-public-health-f1500964bf5e062db25a9762534e1c2d" target="_blank" rel="noopener">released guidance</a> recommending against vaccinations for healthy children, contradicting federal public health leaders whose advice says <a href="https://apnews.com/article/coronavirus-pandemic-science-health-centers-for-disease-control-and-prevention-7cb5761c688f963c2f28957b32ea1405" target="_blank" rel="noopener">all kids should get the shots</a>. In response, the American Academy of Pediatrics and its Florida chapter issued written statements reiterating support for vaccinating eligible children ages 5 and older against COVID-19.DeSantis, who is contemplating a GOP presidential bid, also <a href="https://apnews.com/article/ron-desantis-health-florida-covid-f90dbf672338461457f6c30633398e90" target="_blank" rel="noopener">has requested</a> that a grand jury be convened to investigate any wrongdoing with respect to the COVID-19 vaccines. DeSantis' request argues that pharmaceutical companies had a financial interest in creating a climate in which people believed that getting a coronavirus vaccine would ensure they couldn't spread the virus to others.The Florida Supreme Court agreed to the request last December.

Florida surgeon general appointed by DeSantis cut data from a COVID-19 vaccine safety study

<ul class="summary-list"><li>In March, a <keyword id="6361948" type="UNKNOWN" weightage="60" keywordseo="cybersecurity">cybersecurity</keyword> researcher discovered a <keyword id="151277" type="CITY" weightage="60" keywordseo="CVs">CVS</keyword> database including 1 billion data points.</li><li>It contained searches for COVID-19 vaccines and medications, the researcher said on <a href="https://www.websiteplanet.com/blog/cvs-health-leak-report/">Website Planet</a>.</li><li>Researcher Jeremiah Fowler told <a href="https://www.forbes.com/sites/thomasbrewster/2021/06/16/cvs-accidentally-leaks-1-billion-website-records-including-covid-19-vaccine-searches/?sh=1d1665452c4f">Forbes</a> CVS took the data set down within one day of him notifying the firm.</li></ul>A dataset containing 1 billion data points from CVS customers, including searches for medications and COVID-19 vaccines made on CVS.com, was inadvertently posted online. Cybersecurity researcher Jeremiah Fowler discovered a non-password protected database belonging to CVS Health on March 31. Fowler posted his findings on <a href="https://www.websiteplanet.com/blog/cvs-health-leak-report/">Website Planet</a>.The data consisted of searches for medications, COVID-19 vaccines, and other CVS products, Fowler reported. Some searches contained email addresses and "Visitor IDs" that could have matched searches with personal identifying information.Read more: <a href="https://www.businessinsider.com/genomics-company-helix-helping-cdc-track-coronavirus-variants-2021-6">How DNA-testing startup Helix became one of the nation's leading coronavirus tracking labs</a>Fowler told <a href="https://www.forbes.com/sites/thomasbrewster/2021/06/16/cvs-accidentally-leaks-1-billion-website-records-including-covid-19-vaccine-searches/?sh=1d1665452c4f">Forbes</a> he did not download the full dataset for ethical reasons, as he did not want to collect personal data. The researcher added CVS took down public access to the database within one day of Fowler notifying them."The bad part about this finding was just how big it was," Fowler told Forbes in an interview. "In a small sampling of records there were emails from all major email providers."CVS told Insider the firm determined the database, which was hosted by a third-party vendor, did not contain personal information of customers, members or patients. The firm worked with the vendor to quickly take down the database."We've addressed the issue with the vendor to prevent a recurrence and we thank the researcher who notified us about this matter," a CVS spokesperson said in a statement.

CVS accidentally exposed a database containing 1 billion data points, including searches for medications and COVID-19 vaccines

<ul class="summary-list"><li>President Biden tested positive for COVID-19 on July 21 and was "experiencing very mild symptoms," the White House said. </li><li>Days later, Biden tested negative but tested positive again on July 30 with a rebound case.</li></ul>President <keyword id="99719" type="UNKNOWN" weightage="60" keywordseo="joe-biden" source="Orion">Joe Biden</keyword> tested <a href="https://www.businessinsider.com/biden-tests-positive-covid-19-again-coronavirus-pandemic-2022-7">positive for COVID-19 again</a> on Saturday. He had previously tested negative multiple times earlier in the week. Upon his <a href="https://www.businessinsider.com/biden-tests-positive-for-covid-19-white-house-announces-2022-7">first infection</a> on July 21, medical experts at the time told Insider the president's chances of developing severe disease were low. The White House said that Biden was "experiencing very mild symptoms" and had already begun taking Paxlovid, an antiviral drug used to combat COVID-19. In a <a href="https://twitter.com/JakeSherman/status/1550133002436427776?s=20&amp;t=0HhhbXhu7_iJ8GUuMVkGCA">memo</a>, the president's doctor said he had a runny nose, a dry cough, and fatigue.<a href="https://www.whitehouse.gov/wp-content/uploads/2022/07/Letter-7.22.pdf">Biden's doctor had said</a> his oxygen rates were normal and that he'd taken Tylenol overnight after having a temperature of 99.4 degrees. He also noted that the president developed a "loose" cough and a deeper voice.Biden tested negative for COVID-19 on July 26 and 27, when he announced he was going <a href="https://twitter.com/POTUS/status/1552296813230710784?s=20&amp;t=AeHY3J5JplMUWoAX6Ko84A">"back to the Oval"</a> after isolating. But days later, on Saturday, Biden tested positive for again, <a href="https://twitter.com/POTUS/status/1553451657748512768?s=20&amp;t=2vSR378jq05tEXLVIWleYg">tweeting</a>: "I've got no symptoms but I am going to isolate for the safety of everyone around me.""I'm still at work, and will be back on the road soon," he added.Biden, who is 79 and has some mild pre-existing conditions, is in an age bracket with high mortality rates but his health and vaccinations offer greatly enhanced protection. Experts characterized the chances of the commander-in-chief's health taking a severe turn as "incredibly low," a situation likely to require invoking the <a href="https://www.businessinsider.com/25th-amendment-how-can-you-remove-president-from-office-2017-3">25th Amendment</a> and transferring control of the US's nuclear forces to the vice president while he would undergo <a href="https://www.businessinsider.com/medical-care-president-joe-biden-white-house-2022-7">treatment</a> at Walter Reed National Military Medical Center, as happened to his then-unvaccinated predecessor.Biden will need to stop taking two of his regular medications, one that lowers cholesterol and one that's a blood thinner for a heart condition called atrial fibrillation, for as long as he's on Paxlovid."It's a very standard, common thing that we do when we give people Paxlovid," White House COVID-19 coordinator Dr. Ashish Jha said Thursday during a press briefing. "They both get stopped for the five days that he's on Paxlovid, and then they get restarted. And it's totally fine and pretty normal practice."Biden's doctor, Kevin O'Connor, noted last week that Biden has already received four COVID-19 shots. Given his vaccination status, O'Connor was bullish on Biden's chances for a swift recovery."The President is fully vaccinated and twice-boosted, so I anticipate that he will respond favorably, as most maximally protected patients do," O'Connor wrote.<h2>4th shots are key for older adults </h2>The <a href="https://www.who.int/news/item/17-05-2022-interim-statement-on-the-use-of-additional-booster-doses-of-emergency-use-listed-mrna-vaccines-against-covid-19">World Health Organization</a> and the US <a href="https://www.cdc.gov/mmwr/volumes/71/wr/mm7129e1.htm">Centers for Disease Control and Prevention both recommend</a> that older adults should get an additional (fourth) boost, to better protect them against severe disease with COVID-19.According to a June <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278185/">study of older adults from Israel</a>, having the second boost provides elders much greater protection from bad <keyword id="11893194" type="UNKNOWN" weightage="60" keywordseo="coronavirus" source="Orion">coronavirus</keyword> outcomes. "Compared with individuals who received 3 doses," the study says, "those who received a fourth dose had a 3.5-fold lower rate of severe disease during a 6-week follow up."Robust recent data on <a href="https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(22)00162-4/fulltext">tens of thousands of Swedes shows</a>, likewise, that a fourth dose can help guard against death from COVID, even "in the oldest and frailest" patients, and "after the emergence of the Omicron variant.""If you are over the age of 50, and if you've not gotten a vaccine shot in the year 2022, you need to go get one. You need to go get one now," Jha said Thursday.<h2>Biden's 'a healthy and vigorous person with 4 shots'</h2>Dr. Michael Klompas, an infectious disease expert at Harvard Medical School, told Insider that Biden is also generally in good health, which bodes well for his chances of having a mild case. Biden's <a href="https://www.whitehouse.gov/wp-content/uploads/2021/11/President-Biden-Current-Health-Summary-November-2021.pdf">2021 health summary</a> presented by O'Connor did not reveal any severe health issues or comorbidities."He's old, yes, but he seems to otherwise be pretty vigorous, there's nothing I've heard to say that he's got comorbid illnesses, like bad heart disease, or lung disease, or liver disease, or cancer, or immunocompromised conditions," Klompas said. "I'd say on the basis of that, of being simply old, otherwise a healthy and vigorous person with 4 shots, his risk of a bad outcome's incredibly low."Dr. Seth Cohen, medical director of infection prevention at the University of Washington Medical Center, echoed Klompas and the booster data. Neither Cohen or Klompas have personally evaluated Biden, or been consulted on his care by White House staff.Cohen said that Biden's vaccination status decreases his chances of severe illness."We also have very, very strong data to show how crucial it is to be fully boosted in terms of preventing severe outcomes from Omicron," Cohen said. "Hopefully, that is giving a lot of people some peace of mind."

Biden is 79, vaccinated, and twice boosted. Here's his risk of severe COVID.

<ul class="summary-list"><li>A data leak revealed over 92,000 donors who shelled out more than $8 million to the <keyword id="13123564" type="UNKNOWN" weightage="60" keywordseo="freedom-convoy" source="Orion">Freedom Convoy</keyword>.</li><li>Texas CEO Benjamin Pogue's email was linked to a $20,000 donation to the protest, <a href="https://gizmodo.com/texas-ceo-ben-pogue-named-in-freedom-convoy-donation-da-1848542825?rev=1644956576543">Gizmodo reported.</a></li></ul>Benjamin Pogue, the CEO of a Texas construction company and a supporter of Donald Trump, has been linked to a $20,000 donation to the ongoing vaccine mandate protests in Canada, according to multiple reports.On Sunday night, <a href="https://www.vice.com/en/article/k7wpax/freedom-convoy-givesendgo-donors-leaked">hackers leaked</a> the names of over 92,000 donors who had given millions of dollars to the protesters known as the "Freedom Convoy" via GiveSendGo. Pogue is named among some of the top donors on the Christian crowd-sourcing site and his email is linked to the donation, <a href="https://gizmodo.com/texas-ceo-ben-pogue-named-in-freedom-convoy-donation-da-1848542825?rev=1644956576543">Gizmodo and The Dallas Morning News reported.</a>A spokesperson for Pogue told Insider that the CEO "has no comment on this issue."In 2020, Pogue donated over $385,000 to Trump's reelection efforts, including providing the former president with the <a href="https://apnews.com/article/virus-outbreak-donald-trump-business-kimberly-guilfoyle-elections-d6a2c54227b7acbf36360c5c07630419">use of Pogue's own private jet.</a> The vaccine mandate protest has been <a href="https://www.businessinsider.com/reviews/out?u=https%3A%2F%2Fwww.wsj.com%2Farticles%2Ffreedom-convoy-protesters-in-canadas-capital-city-dig-in-after-tougher-measures-11644947631%3Fmod%3Dhp_lead_pos12">linked</a> to Trump supporters in multiple instances. Several <keyword id="11893589" type="UNKNOWN" weightage="60" keywordseo="news" source="Orion">news</keyword> outlets have <a href="https://www.businessinsider.com/videos-of-trucking-vaccine-mandate-protest-truckers-camp-outside-capital-2022-1">posted photos</a> of the protest that include hats and signs referencing Trump and the slogan "Make Canada Great Again." <a href="https://ottawa.ctvnews.ca/protesters-on-horseback-participate-in-freedom-convoy-demonstration-in-downtown-ottawa-1.5769508">Local news reported</a> that during the first week of the protests a man was seen riding through the protesters on horseback, carrying a "Trump 2024" flag.Trump and several political figures, including Ben Shapiro and Rep. Majorie Taylor Green (R-GA), have <a href="https://www.businessinsider.com/elon-musk-donald-trump-praised-canadian-trucker-vaccine-mandate-protest-2022-1">expressed support</a> for the movement. The former president <a href="https://www.businessinsider.com/elon-musk-donald-trump-praised-canadian-trucker-vaccine-mandate-protest-2022-1">said</a> the protesters were "doing more to defend American freedom than our own leaders by far," during a rally in Conroe, Texas on January 30. <a href="https://www.vice.com/en/article/k7wpax/freedom-convoy-givesendgo-donors-leaked">Vice reported</a> that over half of the donations on the donation site originated from the US, according to the leaked data, which has since been removed online. Other major US donors that were revealed in the leak reportedly include American software billionaire and past Republican Party supporter Thomas Siebel, who donated $90,000 to the Freedom Convoy, according to the data. Siebel did not respond to a request for comment from Insider.Last week, an Ontario court <a href="https://www.npr.org/2022/02/10/1080022827/a-canadian-judge-has-frozen-access-to-donations-for-the-trucker-convoy-protest">held up</a> funding for the Freedom Convoy by freezing $8.4 million that the group raised on GiveSendGo. Since then, Canadian authorities have begun targeting crypto donations to protesters. Previously, the convoy raised more than $10 million on GoFundMe until the platform <a href="https://www.bbc.com/news/world-us-canada-60267840">shut the page down</a> and refunded the money earlier in the month.On Monday, Canadian Prime Minister Justin Trudeau <a href="https://www.businessinsider.com/justin-trudeau-invokes-national-emergency-powers-trucker-protests-canada-2022-2">invoked emergency powers</a> for the first time in Canada's history after calling the protesters a <a href="https://www.youtube.com/watch?v=cWv-1z5hjzA">"small fringe minority"</a> only a few weeks prior. The Emergencies Act allows the government to temporarily override civil rights to break up the blockades of protesters who have flooded Canada's capital and taken up blockades across the country.The Freedom Convoy has clogged city streets in Ottawa since convoys of <keyword id="6374551" type="UNKNOWN" weightage="60" keywordseo="truckers" source="Orion">truckers</keyword> began <a href="https://www.businessinsider.com/truckers-protest-vaccine-mandate-roll-to-canadian-capital-2022-1">rolling into the capital</a> on January 21. Last week, members of the group <a href="https://www.businessinsider.com/canada-trucker-protests-cause-traffic-delay-major-detroit-bridge-2022-2">blocked a vital bridge</a> between Detroit and Canada, snarling international trade. Since, the protests have spread throughout the province into Windsor and Sarnia.Canada's vaccine mandate for truckers went into effect on January 15. The <a href="https://globalnews.ca/news/8514082/canada-truck-drivers-vaccination-covid/">new rules</a> require US truckers to present proof of vaccination to cross the border and unvaccinated Canadian truckers to get a COVID-19 test and quarantine when they reenter from the US. The US imposed a <a href="https://www.businessinsider.com/truckers-vaccine-mandate-drivers-crossing-us-border-biden-2021-11">similar mandate</a> on January 22.

Leaked data reportedly reveals a Texas construction CEO who once loaned Trump his private jet is a top donor to the 'Freedom Convoy' trucker protest

<keyword id="3658" type="General" weightage="50" keywordseo="india" source="Orion">India</keyword> on Monday recorded 1,839 fresh COVID-19 infections, while the number of active cases came down to 25,178 from 27,212 the day before, according to <keyword id="920967" type="General" weightage="80" keywordseo="union-health-ministry-data" source="Orion">Union health ministry data</keyword>. The COVID-19 tally now stands at 4.49 crore (4,49,71,469). The death toll climbed to 5,31,692 with 11 fatalities, the data updated at 8 am stated. At 25,178, the active cases comprise 0.06 per cent of the total infections. The national COVID-19 recovery rate was recorded at 98.76 per cent, the ministry said. The number of people who have recuperated from the disease surged to 4,44,14,599, while the case fatality rate stood at 1.18 per cent. According to the ministry's website, 220.66 crore doses of COVID-19 vaccines have been administered so far under the nationwide vaccination drive. SEE ALSO: <a href="https://www.businessinsider.in/stock-market/news/adani-group-paytm-britannia-marico-among-stocks-in-focus/articleshow/100062286.cms">Sensex, Nifty50 likely to open in the green: Adani group, Paytm, Britannia, Marico among stocks in focus</a> <a href="https://www.businessinsider.in/personal-finance/news/how-hra-exemption-can-help-you-save-tax-in-2023-24/articleshow/100014412.cms">How HRA exemption can help you save tax in 2023-24</a> <a href="https://www.businessinsider.in/tech/news/fake-verified-facebook-pages-luring-users-into-clicking-malicious-links/articleshow/100047334.cms">Fake verified Facebook pages luring users into clicking malicious links</a>

India adds 1,839 Covid infections, active cases down to 25,178

There has been a rising spate of heart attacks in India, particularly post Covid-19 pandemic. While some blame vaccines for triggering heart issues, health experts have allayed such fears, citing no evidence to prove that vaccines can cause heart attacks. According to the Global Burden of Disease, nearly a quarter (24.8 per cent) of all deaths in India is due to cardiovascular diseases (CVD). Recent reports showed many young celebrities, artistes, athletes, sportspersons -- who usually remain fit and have no history of CVD -- face heart attacks, while some also succumbed to it. "The increase in heart attacks is best explained by the fact that almost everyone has had <keyword id="8764262" type="General" weightage="100" keywordseo="covid" source="Orion">Covid</keyword>, some people multiple times," Dr Anurag Agrawal, Dean, Biosciences and Health Research, Trivedi School of Biosciences, Ashoka University, told IANS. "The risk of cardiovascular complications including heart attacks, is increased in individuals who have acute <keyword id="8764728" type="General" weightage="50" keywordseo="covid-19" source="Orion">Covid 19</keyword>," added Dr <keyword id="1979580" type="General" weightage="50" keywordseo="vivekanand-jha" source="Orion">Vivekanand Jha</keyword>, Executive Director, George Institute India. Several studies have added evidence that Covid infection is behind the rising heart attacks. Research has shown that Covid has the potential to unmask silent cardiac symptoms among people with previously undiagnosed heart disease. A study by the British Heart Foundation has found that Covid can cause heart and kidney inflammation along with systemic body inflammation. Another study of nearly 160,000 people published in Cardiovascular Research, a journal of the European Society of Cardiology, early this year showed that Covid is associated with higher risks of cardiovascular disease and death in the short-and long-term. Compared to uninfected individuals, the likelihood of Covid patients dying was up to 81 times higher in the first three weeks of infection and remained five times higher up to 18 months later. Even a mild case of Covid can increase a person's risk of cardiovascular problems for at least a year after diagnosis, according to a study published in the journal Nature Medicine, last year. Researchers found that rates of many conditions, such as heart failure and stroke, were substantially higher in people who had recovered from Covid than in similar people who hadn't had the disease. However, some also flagged concerns with Covid vaccines. According to the CDC, evidence from multiple monitoring systems in the US and around the globe support a causal association between mRNA COVID-19 vaccines (i.e., <keyword id="4912868" type="General" weightage="50" keywordseo="moderna" source="Orion">Moderna</keyword> or Pfizer-BioNTech) and myocarditis and pericarditis. Media reports have also cited that the Oxford-AstraZeneca's jab, administered in India as Covishield, is linked with increasing clotting tendency leading to occlusion of arteries or veins. Recently, eminent British-Indian Cardiologist Dr Aseem <keyword id="35" type="General" weightage="50" keywordseo="malhotra" source="Orion">Malhotra</keyword> said that it was even "worse" in terms of cardiovascular effects, heart attacks and strokes. "The rise in heart attacks is not directly linked with the Covid vaccine but with covid infection mainly as there are lots of things that Covid can do with the cardiovascular system. There are reports of increased blood stickiness too in Covid infected people," Dr Amit Prasad, Associate Professor, School of Biosciences and Bioengineering, IIT Mandi, told IANS. "Even before vaccination started, such a link between Covid and an increase in future heart attacks could be seen. This observation is from 2020 data and thus clearly shows that the risk of increase in heart attacks started before vaccination started," added Agrawal. Dr. Vivekanand Jha, Executive Director, George Institute India said: "There is no evidence to suggest that heart attacks are linked to Covid vaccines." "The risk of cardiovascular complications including heart attacks, is increased in individuals who have acute Covid 19." Meanwhile, taking note of the rising heart attacks, Union Health Minister <keyword id="2607815" type="General" weightage="50" keywordseo="mansukh-mandaviya" source="Orion">Mansukh Mandaviya</keyword> said earlier this week that the Indian Council of Medical Research (ICMR) has started a research on the sudden rise in cardiac events after Covid-19. The results are expected in the next two months. 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Experts allay fears: It is Covid that triggers heart attacks, not vaccines

People exposed to higher levels of <keyword id="55910" type="General" weightage="20" keywordseo="air-pollution" source="Orion">air pollution</keyword> before the pandemic are likely to have lower antibody responses to Covid-19 vaccines, suggests a study. In particular, exposure to fine particulate matter (PM2.5), nitrogen dioxide (NO2) and blank carbon (BC) was associated with about a 10 per cent decrease in IgM and IgG antibody responses in people without prior infection, said researchers from the Barcelona Institute for Global Health (ISGlobal), and the Germans Trias i Pujol Research Institute (IGTP) in Spain. The fact that previous infections lead to higher vaccine responses could explain why the effect of pollutants was only observed in people without a prior infection. However, the role of long-term exposure to air pollution on hybrid immunity (infection plus vaccination) deserves further investigation, the researchers warned, in the study published in Environmental Health Perspectives. "Air pollution can induce chronic inflammation, which has been associated with a negative effect on vaccine efficacy," said Carlota Dobano, researcher from ISGlobal. "Our findings are consistent with evidence that persistent organic pollutants reduce vaccine responses in children," she added. Air pollutants have been shown to affect immune responses. Previously it has been linked to adverse health outcomes, including lung cancer, cardiovascular and respiratory disease, and diabetes. The team analysed data from 927 participants (aged 40 to 65 years), who answered questionnaires and gave blood samples in the summer of 2020 (right after the first lockdown) and in 2021 (after the start of Covid-19 vaccination). All had received one or two doses of the main Covid-19 vaccines administered in Spain (made by AstraZeneca, Pfizer or Moderna). The research team measured IgM, IgG and IgA antibodies to five viral antigens (three of them on the Spike protein contained in the vaccine). Exposure to fine particulate matter (PM2.5), black carbon (BC), nitrogen dioxide (NO2) and ozone (O3) was estimated for each participant based on his or her address before the pandemic. The results show that in uninfected individuals, pre-pandemic exposure to PM2.5, NO2 and BC was associated with a 5 per cent to 10 per cent reduction in vaccine-induced Spike antibodies. The decrease in antibodies was shown both for early IgM responses and late responses measured by IgG. The IgG response after the first dose peaked later in participants exposed to higher air pollution levels, and lower IgG levels persisted for several months after vaccination. Results were similar for the three vaccines. The study did not look at whether the reduction in antibody responses led to an increased risk of breakthrough infections and their severity. However, the findings add to the growing body of evidence on the adverse effects of air pollution even at the relatively low levels observed in Western Europe, the researchers said, while calling for stricter air pollution limits. SEE ALSO: <a href="https://www.businessinsider.in/business/news/ipl-2023-to-drive-fantasy-sports-companies-to-2900-3100-crore-revenue/articleshow/99285556.cms">IPL 2023 to drive fantasy sports companies to ₹2,900-3,100 crore revenue, fueled by Tier-2 cities and exciting prizes</a> <a href="https://www.businessinsider.in/tech/news/google-makes-it-easier-for-users-to-delete-their-account-and-data-from-applications/articleshow/99289621.cms">Google makes it easier for users to delete their account and data from applications</a> <a href="https://www.businessinsider.in/tech/news/9-out-10-tvs-sold-in-india-in-2022-were-smart-tvs-and-nearly-all-of-these-tvs-are-assembled-locally/articleshow/99262205.cms">9 out 10 TVs sold in India in 2022 were smart TVs, and nearly all of these TVs are assembled locally</a>

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