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Several people lost their sense of smell or <keyword id="84707" type="COMPANY" weightage="20" keywordseo="Taste">taste</keyword> weeks ago globally and are still waiting for it to come back and now, researchers have identified an association between sensory loss and novel <keyword id="1754604" type="PERSON" weightage="20" keywordseo="coronavirus">coronavirus</keyword> 2019 (COVID-19) infection, indicating that loss of smell and taste may be considered as early <keyword id="44308" type="ORGANIZATION" weightage="20" keywordseo="Symptoms">symptoms</keyword> of the deadly disease. Interestingly, the <keyword id="6355244" type="UNKNOWN" weightage="20" keywordseo="study">study</keyword> also found that persons who reported experiencing a sore throat more often tested negative for COVID-19. The team from University of California-San Diego found high prevalence and unique presentation of certain sensory impairments in <keyword id="6364395" type="UNKNOWN" weightage="20" keywordseo="patients">patients</keyword> positive with COVID-19. Of those who reported a loss of smell and taste, the loss was typically profound, not mild. "Based on our study, if you have smell and taste loss, you are more than 10 times more likely to have COVID-19 infection than other causes of infection. The most common first sign of a COVID-19 infection remains fever, but fatigue and loss of smell and taste follow as other very common initial symptoms," explained study researcher <keyword id="9052203" type="PERSON" weightage="20" keywordseo="carol-yan">Carol Yan</keyword> from UC San Diego. "We know COVID-19 is an extremely contagious virus. This study supports the need to be aware of smell and taste loss as early signs of COVID-19," Yan added. For the findings, published in the journal International Forum of Allergy and Rhinology, the research team surveyed 1,480 patients with flu-like symptoms and concerns regarding potential COVID-19 infection who underwent testing at <keyword id="8763690" type="LOCATION" weightage="20" keywordseo="UC-San-Diego-Health">UC San Diego Health</keyword> from March 3 through March 29, 2020. Within that total, 102 patients tested positive for the virus and 1,378 tested negatives. The study included responses from 59 COVID-19-positive patients and 203 COVID-19-negative patients. Encouragingly, the rate of recovery of smell and taste was high and occurred usually within two to four weeks of infection. "Our study not only showed that the high incidence of smell and taste is specific to COVID-19 infection but we fortunately also found that for the majority of people sensory recovery was generally rapid," said Yan. "Among the COVID-19 patients with smell loss, more than 70 per cent had reported improvement of smell at the time of the survey and of those who hadn't reported improvement, many had only been diagnosed recently," she added. Sensory return typically matched the timing of disease recovery. In an effort to decrease the risk of virus transmission, UC San Diego Health now includes loss of smell and taste as a screening requirement for visitors and staff, as well as a marker for testing patients who may be positive for the virus. "It is our hope that with these findings other institutions will follow suit and not only list smell and taste loss as a symptom of COVID-19, but use it as a screening measure for the virus across the world," Yan said. SEE ALSO:<a href="https://www.businessinsider.in/topic/coronavirus">Coronavirus News and Updates</a> <a href="https://www.businessinsider.in/india/news/how-to-check-coronavirus-symptoms-at-home/articleshow/74960334.cms">What are the Coronavirus symptoms and how to check for them at home</a>

Smell and taste loss an early sign of Covid-19, scientists confirm

Los Angeles, Apr 14 () Researchers have reported the first empirical findings linking the loss of smell and taste in patients with COVID-19, a finding that may become a new clinical screening measure for the virus. According to the study, published in the journal International Forum of Allergy and Rhinology, people with influenza-like symptoms, and a dysfunction of smell and taste, are strongly associated with COVID-19 infection. "Based on our study, if you have smell and taste loss, you are more than 10 times more likely to have COVID-19 infection than other causes of infection," said Carol Yan, an otolaryngologist and study co-author from the University of California San Diego in the US. While the most common first sign of a COVID-19 infection remains fever, Yan said, fatigue and loss of smell and taste follow as other very common initial symptoms. "We know COVID-19 is an extremely contagious virus. This study supports the need to be aware of smell and taste loss as early signs of COVID-19," She added. The researchers surveyed 1,480 patients with flu-like symptoms and concerns regarding potential COVID-19 infection who underwent testing at UC San Diego Health from March 3 through March 29, 2020. Of the patients surveyed, 102 tested positive for the virus and 1,378 tested negative. According to the study, there is a high prevalence and unique presentation of certain sensory impairments in patients positive with COVID-19. Of those who reported loss of smell and taste, the scientists said, the loss was typically profound, not mild. But they added that the rate of recovery of smell and taste was high and occurred usually within two to four weeks of infection. "Our study not only showed that the high incidence of smell and taste is specific to COVID-19 infection, but we fortunately also found that for the majority of people sensory recovery was generally rapid," Yan said. "Among the COVID-19 patients with smell loss, more than 70 per cent had reported improvement of smell at the time of survey and of those who hadn't reported improvement, many had only been diagnosed recently," she added. The researchers also found that persons who reported experiencing a sore throat more often tested negative for COVID-19. Based on the findings, UC San Diego Health has included loss of smell and taste as a screening requirement for visitors and staff, as well as a marker for testing patients who may be positive for the virus. Respondents in the study were most often persons with milder forms of COVID-19 infection who did not require hospitalization or intubation. According to the scientists, other known symptoms of COVID-19 include fever, fatigue, cough, and difficulty breathing. The findings, Yan said, underline the importance of identifying early or subtle symptoms of COVID-19 infection in people who may be at risk of transmitting the disease as they recover within the community. "It is our hope that with these findings other institutions will follow suit and not only list smell and taste loss as a symptom of COVID-19, but use it as a screening measure for the virus across the world," she added. VIS VISVIS

Smell, taste loss symptoms associated with COVID-19: Study

Los Angeles, Apr 28 () People who experience loss of smell as one of the COVID-19 symptoms are likely to have a mild to moderate clinical course of the disease, according to a study which may help health care providers determine which patients require hospitalisation. The findings, published in the journal International Forum of Allergy &amp; Rhinology, follows an earlier study that validated the loss of smell and taste as indicators of infection with the novel coronavirus, SARS-CoV-2. According to the scientists from the University of California (UC) San Diego Health in the US, patients who reported loss of smell were 10 times less likely to be hospitalised for COVID-19 compared to those without the symptom. "One of the immediate challenges for health care providers is to determine how to best treat persons infected by the novel coronavirus," said Carol Yan, first author of the current study and rhinologist from the UC San Diego Health. "If they display no or mild symptoms, can they return home to self-quarantine or will they likely require hospitalisation? These are crucial questions for hospitals trying to efficiently and effectively allocate finite medical resources," Yan said. The findings, according to the researchers, suggest that loss of smell may be predictive of a milder clinical course of COVID-19. "What's notable in the new findings is that it appears that loss of smell may be a predictor that a SARS-CoV-2 infection will not be as severe, and less likely to require hospitalisation," Yan said. "If an infected person loses that sense, it seems more likely they will experience milder symptoms, barring other underlying risk factors," she added. Risk factors for COVID-19 previously reported by other studies include age, and underlying medical conditions, such as chronic lung disease, serious heart conditions, diabetes, and obesity. In the current study, the scientists made a retrospective analysis between March 3 and April 8 including 169 patients who tested positive for COVID-19 at UC San Diego Health. They assessed olfactory and gustatory data for 128 of the 169 patients, 26 of whom required hospitalisation. According to the researchers, patients who were hospitalised for COVID-19 treatment were significantly less likely to report anosmia or loss of smell -- 26.9 per cent compared to 66.7 per cent for COVID-19-infected persons treated as outpatients. Similar percentages were found for loss of taste, known as dysgeusia, they said. "Patients who reported loss of smell were 10 times less likely to be admitted for COVID-19 compared to those without loss of smell," said study co-author Adam S. DeConde. "Moreover, anosmia was not associated with any other measures typically related to the decision to admit, suggesting that it's truly an independent factor and may serve as a marker for milder manifestations of Covid-19," DeConde said. The researchers suspect that the findings hint at some of the physiological characteristics of the infection. "The site and dosage of the initial viral burden, along with the effectiveness of the host immune response, are all potentially important variables in determining the spread of the virus within a person and, ultimately, the clinical course of the infection," DeConde said. If the SARS-CoV-2 virus initially concentrates in the nose and upper airway, where it impacts olfactory function, that may result in an infection that is less severe and sudden in onset, decreasing the risk of overwhelming the host immune response, respiratory failure, and hospitalisation, the scientists added. "This is a hypothesis, but it's also similar to the concept underlying live vaccinations," DeConde explained. "At low dosage and at a distant site of inoculation, the host can generate an immune response without severe infection," he added. Loss of smell, according to the study, might also indicate a robust immune response which has been localised to the nasal passages, limiting effects elsewhere in the body. Citing the limitations of the study, the scientists said they relied upon self-reporting of anosmia from participants, which posed a greater chance of recall bias among patients once they had been diagnosed with COVID-19. They added that patients with more severe respiratory disease requiring hospitalisation may not be as likely to recognise or recall the loss of smell. So the researchers said more expansive studies are needed for validating the results. VIS VISVIS

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Smell and taste loss an early sign of Covid-19, scientists confirm

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Smell, taste loss symptoms associated with COVID-19: Study

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Loss of smell may indicate mild to moderate COVID-19: Study

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