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After two cases of the <keyword id="11445972" type="UNKNOWN" weightage="20" keywordseo="delta-plus">Delta plus</keyword> strain were found in Deoria and Gorakhpur, a patient has now tested <keyword id="6439681" type="UNKNOWN" weightage="20" keywordseo="positive">positive</keyword> to the <keyword id="2139218" type="ENTERTAINMENT" weightage="20" keywordseo="Kappa">Kappa</keyword> strain of Covid-19 in Sant Kabir Nagar. The patient, a 66-year-old man, has died. The strain was detected during the genome sequencing exercise. His sample was collected on June 13 as a routine and sent to CSIR's Institute of Genomics and Integrative Biology, <keyword id="6358777" type="UNKNOWN" weightage="20" keywordseo="New-Delhi">New Delhi</keyword> that has confirmed the Kappa strain in the sample. Like <keyword id="6383835" type="ORGANIZATION" weightage="20" keywordseo="delta">Delta</keyword> plus, Kappa too has been declared as a variant of concern. Head of microbiology department at <keyword id="6355646" type="UNKNOWN" weightage="20" keywordseo="BRD-Medical-College">BRD Medical College</keyword>, Amresh Singh, said the patient had tested Covid positive on May 27 and was brought to the medical college on June 12. The sample was taken on June 13. "The patient died in the course of treatment on June 14. He had no travel history," Singh said. Health officials said more than 2,000 samples have been sent for genome sequencing from the state. Two cases of Delta Plus strain were recorded for the first time in <keyword id="6357713" type="COMPANY" weightage="20" keywordseo="Uttar-Pradesh">Uttar Pradesh</keyword> this week. Officials said that since none of the three patients had a travel history, it suggests the virus was mutating in the state. SEE ALSO - <a href="https://www.businessinsider.in/tech/news/google-calendars-new-rsvp-option-will-let-you-specify-how-you-want-to-attend-a-meeting/articleshow/84237490.cms">Google Calendar’s new RSVP option will let you specify how you want to attend a meeting</a> <a href="https://www.businessinsider.in/business/corporates/news/tcs-hires-over-20000-in-june-quarter-its-highest-ever-quarterly-addition/articleshow/84240423.cms">TCS has loaded up half a million peeps as it expects many to move on</a>

After Delta Plus, now coronavirus Kappa variant found in Uttar Pradesh

<ul><li>Serum Institute of India will begin human trials of Oxford-AstraZeneca’s COVID-19 vaccine candidate in India today. </li><li>The hospital has been given a target of enlisting 300 to 350 volunteers. Those chosen for receiving a dose of vaccine will be in the age group of 18 to 99 years. </li><li>The other site for phase 2 trial in Pune, BJ Medical College, is ready and waiting for the vaccine candidate to arrive. The human trials there are set to begin there next week. </li><li> On successful completion of the trials at all sites, the vaccine will be launched under the brand name “Covishield” </li></ul>Serum Institute of India will begin human trials of Oxford-AstraZeneca’s COVID-19 vaccine candidate in India today at Bharti Vidyapeeth Medical College and <a href="https://indianexpress.com/article/cities/pune/pune-first-dose-of-covishield-to-be-given-at-bharati-hospital-today-6569763/">Hospital in Pune. </a> "To start with we have identified five volunteers who will undergo COVID-19 and antibodies tests. Those whose reports are negative will be shortlisted for vaccination on Wednesday," told Dr Sanjay Lalwani, Medical Director, Bharti Vidyapeeth''s Medical College and Hospital and Research Centre PTI. The hospital has been given a target of enlisting 300 to 350 volunteers. Those chosen for receiving a dose of vaccine will be in the age group of 18 to 99 years. The other site for phase 2 trial in Pune, BJ Medical College — to which the Sassoon General Hospital is attached — is ready and waiting for the vaccine candidate to arrive. The human trials there are set to begin there next week. SII has selected 14 locations for the trial — <table style="border-width: initial; border-style: none; width: 468pt; table-layout: fixed;"></colgroup><tbody><tr><td style="border-left:solid #000000 1pt;border-right:solid #000000 1pt;border-bottom:solid #000000 1pt;border-top:solid #000000 1pt;vertical-align:top;padding:5pt 5pt 5pt 5pt;overflow:hidden;overflow-wrap:break-word;">The ICMR-Regional Medical Research Centre, Gorakhpur </td><td style="border-left:solid #000000 1pt;border-right:solid #000000 1pt;border-bottom:solid #000000 1pt;border-top:solid #000000 1pt;vertical-align:top;padding:5pt 5pt 5pt 5pt;overflow:hidden;overflow-wrap:break-word;">Bharti Vidyapeeth''s Medical College and Hospital and Research Centre. </td><td style="border-left:solid #000000 1pt;border-right:solid #000000 1pt;border-bottom:solid #000000 1pt;border-top:solid #000000 1pt;vertical-align:top;padding:5pt 5pt 5pt 5pt;overflow:hidden;overflow-wrap:break-word;"> Jehangir Clinical Development Centre </td></tr><tr><td style="border-left:solid #000000 1pt;border-right:solid #000000 1pt;border-bottom:solid #000000 1pt;border-top:solid #000000 1pt;vertical-align:top;padding:5pt 5pt 5pt 5pt;overflow:hidden;overflow-wrap:break-word;">Andhra Medical College in Visakhapatnam </td><td style="border-left:solid #000000 1pt;border-right:solid #000000 1pt;border-bottom:solid #000000 1pt;border-top:solid #000000 1pt;vertical-align:top;padding:5pt 5pt 5pt 5pt;overflow:hidden;overflow-wrap:break-word;">JSS Academy of Higher Education and Research in Mysuru. </td><td style="border-left:solid #000000 1pt;border-right:solid #000000 1pt;border-bottom:solid #000000 1pt;border-top:solid #000000 1pt;vertical-align:top;padding:5pt 5pt 5pt 5pt;overflow:hidden;overflow-wrap:break-word;"> BJ Medical College </td></tr><tr><td style="border-left:solid #000000 1pt;border-right:solid #000000 1pt;border-bottom:solid #000000 1pt;border-top:solid #000000 1pt;vertical-align:top;padding:5pt 5pt 5pt 5pt;overflow:hidden;overflow-wrap:break-word;">AIIMS in Delhi </td><td style="border-left:solid #000000 1pt;border-right:solid #000000 1pt;border-bottom:solid #000000 1pt;border-top:solid #000000 1pt;vertical-align:top;padding:5pt 5pt 5pt 5pt;overflow:hidden;overflow-wrap:break-word;">Rajendra Memorial Research Institute of Medical Sciences (RMRIMS) in Patna </td><td style="border-left:solid #000000 1pt;border-right:solid #000000 1pt;border-bottom:solid #000000 1pt;border-top:solid #000000 1pt;vertical-align:top;padding:5pt 5pt 5pt 5pt;overflow:hidden;overflow-wrap:break-word;">Nehru Hospital in Gorakhpur </td></tr><tr><td style="border-left:solid #000000 1pt;border-right:solid #000000 1pt;border-bottom:solid #000000 1pt;border-top:solid #000000 1pt;vertical-align:top;padding:5pt 5pt 5pt 5pt;overflow:hidden;overflow-wrap:break-word;">PGIMER in Chandigarh </td><td style="border-left:solid #000000 1pt;border-right:solid #000000 1pt;border-bottom:solid #000000 1pt;border-top:solid #000000 1pt;vertical-align:top;padding:5pt 5pt 5pt 5pt;overflow:hidden;overflow-wrap:break-word;">ABJ Medical College in Pune </td><td style="border-left:solid #000000 1pt;border-right:solid #000000 1pt;border-bottom:solid #000000 1pt;border-top:solid #000000 1pt;vertical-align:top;padding:5pt 5pt 5pt 5pt;overflow:hidden;overflow-wrap:break-word;">AIIMS in Jodhpur </td></tr><tr><td style="border-left:solid #000000 1pt;border-right:solid #000000 1pt;border-bottom:solid #000000 1pt;border-top:solid #000000 1pt;vertical-align:top;padding:5pt 5pt 5pt 5pt;overflow:hidden;overflow-wrap:break-word;">The King Edward Memorial (KEM) in Mumbai </td><td style="border-left:solid #000000 1pt;border-right:solid #000000 1pt;border-bottom:solid #000000 1pt;border-top:solid #000000 1pt;vertical-align:top;padding:5pt 5pt 5pt 5pt;overflow:hidden;overflow-wrap:break-word;">Nair Hospital in Mumbai </td><td style="border-left:solid #000000 1pt;border-right:solid #000000 1pt;border-bottom:solid #000000 1pt;border-top:solid #000000 1pt;vertical-align:top;padding:5pt 5pt 5pt 5pt;overflow:hidden;overflow-wrap:break-word;"> </td></tr></tbody></table> The vaccine will be launched under the brand name “Covishield” once the trials are successfully completed at all the sites. SII has signed two agreements for the supply of Covid-19 vaccines, the first being AstraZeneca-Oxford's candidate, for which the company has agreed to produce up to 1 billion doses for low and middle-income countries. The Oxford University vaccine candidate has received permission to start phase-two and three trials in India earlier this month. The Serum Institute of India would introduce candidate vaccines from AstraZeneca and Novavax for COVID-19 at less than ₹250 per dose in India. The Pune-based institute <a href="https://www.hindustantimes.com/india-news/serum-institute-ties-up-with-bill-gates-foundation-gavi-to-speed-up-covid-19-vaccine-manufacture-process/story-h20YRO9mdooYA8ysqenE9L.html">partnered with </a>Bill &amp; Melinda Gates Foundation to offer up to 100 million doses, with the price capped at $3 for 92 low and middle-income countries (LMIC), including India. According to SII, <a href="https://www.businessinsider.in/science/health/news/serum-institute-may-begin-human-trials-of-oxford-astrazenecas-covid-19-vaccine-candidate-from-august-25/articleshow/77540739.cms">the vaccines will be available as early as the first half of 2021</a> after gaining approvals and qualifications from the World Health Organization (WHO). If successful, Novavax's candidate will be available to all 92 countries, while AstraZeneca's candidate vaccine will be available to 57 Gavi-eligible countries. SEE ALSO: <a href="https://www.businessinsider.in/education/news/heres-a-list-of-instructions-neet-and-jee-aspirants-have-to-follow-during-exam-this-year-according-to-nta/articleshow/77735246.cms">Here’s a list of Instructions NEET and JEE aspirants have to follow during exam this year, according to NTA</a>

Oxford-Astrazeneca COVID-19 Vaccine: Phase II trials will begin in India today

<ul><li>The pharma giant will be meeting principal investigators at 17 different sites across the country. </li><li>Once these formal procedures are completed, SII <a href="https://www.financialexpress.com/lifestyle/health/covid-19-human-trials-of-oxford-vaccine-set-to-begin-in-2-weeks-serum-institute-icmr-members-to-meet-today/2054835/">will begin human trials anytime after August 25. </a> </li><li>The trials will be held at PGIMER Chandigarh, AIIMS in Delhi, ABJ Medical College in Pune, Rajendra Memorial Research Institute of Medical Sciences (RMRIMS) in Patna, and 13 other sites in the country. </li></ul>Serum Institute of India is likely to begin human trials of <keyword id="9605255" type="COMPANY" weightage="20" keywordseo="oxford-astrazeneca">Oxford-AstraZeneca</keyword>’s COVID-19 vaccine candidate in India in the next few weeks. The pharma giant is expected to meet principal investigators on August 14 at 17 different sites across the country. The trials will be held at PGIMER Chandigarh, AIIMS in Delhi, ABJ Medical College in Pune, Rajendra Memorial Research Institute of Medical Sciences (RMRIMS) in Patna, AIIMS in Jodhpur, Nehru Hospital in Gorakhpur, Andhra Medical College in Visakhapatnam and JSS Academy of Higher Education and Research in Mysuru. The virtual meet is going to establish a standard operating procedure for conducting phase 2 and phase 3 clinical trials of the vaccine candidate in India. Once these formal procedures are completed, SII <a href="https://www.financialexpress.com/lifestyle/health/covid-19-human-trials-of-oxford-vaccine-set-to-begin-in-2-weeks-serum-institute-icmr-members-to-meet-today/2054835/">will begin human trials anytime after August 25. </a> SII has signed two agreements for the supply of Covid-19 vaccines, the first being AstraZeneca-Oxford's candidate, for which the company has agreed to produce up to 1 billion doses for low and middle-income countries. The Oxford University vaccine candidate has received permission to start phase-two and three trials in India earlier this month. The Serum Institute of India would introduce candidate vaccines from <keyword id="6409874" type="COMPANY" weightage="20" keywordseo="astrazeneca">AstraZeneca</keyword> and Novavax for COVID-19 at less than ₹250 per dose in India. The Pune-based institute partnered with Bill &amp; Melinda Gates Foundation to offer up to 100 million doses, with the price capped at $3 for 92 low and middle-income countries (LMIC), including India. According to SII, the vaccines will be available as early as the first half of 2021 after gaining approvals and qualifications from the World Health Organization (WHO). If successful, Novavax's candidate will be available to all 92 countries, while AstraZeneca's candidate vaccine will be available to 57 Gavi-eligible countries. (With inputs from IANS) SEE ALSO: <a href="https://www.businessinsider.in/india/news/heres-how-indias-74th-independence-day-celebrations-will-take-place-this-year/slidelist/77523536.cms">Here’s how India’s 74th Independence Day celebrations will take place this year</a> <a href="https://www.businessinsider.in/careers/news/how-much-deloitte-kpmg-ey-and-pwc-accountants-and-consultants-make-from-entry-level-to-executive-roles/articleshow/77533447.cms">How much Deloitte, KPMG, EY, and PwC accountants and consultants make, from entry level to executive roles</a> <a href="https://www.businessinsider.in/science/news/a-dwarf-planet-between-mars-and-jupiter-has-a-salty-ocean-beneath-its-surface-making-it-a-contender-for-alien-life/articleshow/77495476.cms">A dwarf planet between Mars and Jupiter has a salty ocean beneath its surface, making it a contender for alien life</a>

Serum Institute may begin human trials of Oxford-AstraZeneca’s COVID-19 vaccine candidate from August 25

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After Delta Plus, now coronavirus Kappa variant found in Uttar Pradesh

IANS

Oxford-Astrazeneca COVID-19 Vaccine: Phase II trials will begin in India today

BI India Bureau

Serum Institute may begin human trials of Oxford-AstraZeneca’s COVID-19 vaccine candidate from August 25

BI India Bureau

Rahul Gandhi's first interview: Full text

Times Of India

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