Overall, meme trends have shifted from explicitly grappling with coronavirus to simply existing within the context of the pandemic.
Meme tones have shifted from lighthearted and joking pre-lockdown to more serious as things began to settle in. Over the course of April, an estimated 95% of Americans have come under lockdown and the global number of coronavirus cases has crossed 2 million. Despite the staggering figures, as much of the world has been limiting social interaction and staying at home, the pandemic has begun to feel less novel. Memes don't have to explicitly reference coronavirus, or quarantine, to be tied to them in some way.
Coronavirus is the cultural moment, and essentially the default context for all memes or viral events. There have been edits upon edits of the "Gossip Girl" logo, discussions over the best Spider-Man film, and people flooding the timeline with photos of themselves at age 20. Even though content is moving away from being explicitly about the pandemic, it's still a symptom of it.
In short, the memes show something that many of us likely feel to some degree: people are starting to adjust to this new normal, even though the world is still in crisis.