These were the 10 worst-performing stocks in the S&P 500 in 2021

• Despite the S&P 500's 2021 gain of about 30%, there were plenty of member stocks that lost money for investors.
• Low interest rates and a growing economy weren't enough to boost the 70 S&P 500 stocks that generated negative returns in 2021.
• These were the 10 worst-performing S&P 500 stocks in 2021, according to data from Koyfin.
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With the S&P 500 on track to generate a total return of more than 30%, 2021 has been a strong year for investors.

Historically low interest rates, a continued economic expansion, and record earnings helped drive most S&P 500 stocks into positive territory, with some of the top performing stocks jumping as much as 200%.

But there were still about 70 stocks within the popular index that generated negative returns in 2021, including casino stocks and high-fliers from 2020 that have since consolidated their gains.

These were the top 10 worst-performing S&P 500 stocks in 2021, according to data from Koyfin, and based on December 28 closing prices.

10. Fidelity National Information Services

Ticker: FIS
Market Capitalization: $66.6 billion
2021 Performance: -21.7%

9. Wynn Resorts

Ticker: WYNN
Market Capitalization: $10.0 billion
2021 Performance: -23.3%

8. IPG Photonics

Ticker: IPGP
Market Capitalization: $9.1 billion
2021 Performance: -23.7%

7. Citrix Systems

Ticker: CTXS
Market Capitalization: $12.0 billion
2021 Performance: -25.0%

6. Viatris

Ticker: VTRS
Market Capitalization: $16.5 billion
2021 Performance: -25.6%

5. MarketAxess

Ticker: MKTX
Market Capitalization: $15.8 billion
2021 Performance: -26.9%

4. Activision Blizzard

Ticker: ATVI
Market Capitalization: $51.8 billion
2021 Performance: -28.0%

3. Las Vegas Sands

Ticker: LVS
Market Capitalization: $28.8 billion
2021 Performance: -36.6%

2. Global Payments

Ticker: GPN
Market Capitalization: $39.2 billion
2021 Performance: -36.9%

1. Penn National Gaming

Ticker: PENN
Market Capitalization: $8.4 billion
2021 Performance: -42.9%