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A researcher works in a lab that is developing testing for the COVID-19 virus.
- Researchers are testing a wide range of experimental treatments against the novel coronavirus, with clinical trials now happening across the US.
- Business Insider analyzed a federal database of studies to see where most of these trials are happening across the US.
- New York state leads the way with 11 trial listings.
- Fourteen states do not have any listed COVID-19 studies for treatments or vaccines. That includes Indiana and Nevada, which are both states with more than 1,000 confirmed cases.
- Visit Business Insider's homepage for more stories.
Research activity has ramped up in the US against COVID-19, with dozens of clinical trials underway or starting soon testing a range of potential treatment options.
An analysis of a federal database by Business Insider found a wide range of research activity varying by state. New York leads the nation with 11 coronavirus trials in the state.
Many trials are recruiting patients across the country, such as a study led by the National Institutes of Health to test remdesivir, an antiviral. That trial, for instance, is recruiting patients in more than a dozen states.
But 14 states still have no listed coronavirus trials, even as the virus has spread across the nation. Indiana and Nevada both have more than 1,000 confirmed COVID-19 cases but no clinical trials in their states to test experimental treatments.
The most widespread treatments being tested include the antiviral remdesivir, developed by Gilead Sciences, the anti-malaria pill hydroxychloroquine, and Kevzara, an anti-inflammatory arthritis drug developed by Sanofi and Regeneron.
The first US coronavirus vaccine trial is also underway, testing healthy volunteers in Washington state and Georgia.
Business Insider conducted the analysis on April 3. Additional listings are being added daily to the database, which has grown from listing 19 US-based trials a week ago on March 27 to 44 studies.
The analysis is limited to the timeliness of the database. Federal law requires clinical trials to be posted no later than three weeks after a study starts enrolling patients, which could mean some studies aren't yet included. Most researchers post a listing on the site before they start recruiting participants.
Additionally, Business Insider went through the listings to remove trials that were either observational, meaning they are not testing any treatment option, or mentioned COVID-19 in the listing but were not actually focused on the disease. (For example, one study in the District of Columbia focused on high blood pressure was updated to state that it was delayed due to the COVID-19 outbreak.)
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