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- Globally, there are at least 19 vaccines under human trials.
- Of the total, three of the institutions have managed to reach the final Phase III trials —the University of Oxford and China’s state-owned pharmaceutical Sinopharm and Sinovac.
- China — the country where coronavirus first broke — has at least five vaccine candidates under human trials.
Seven months into the coronavirus pandemic, there’s still no cure for the disease. In fact, the Health Organisation believes the coronavirus crisis, in the coming future, is only going to be “worse and worse and worse.”
Globally, there are at least 19 vaccines under human trials. Of the total, three of the institutions have managed to reach the final Phase III trials —the University of Oxford and China’s state-owned pharmaceutical Sinopharm and Sinovac.
China — the country where coronavirus first broke — has at least five vaccine candidates under human trials.
These are the coronavirus vaccine under human trials right now
ChAdOx1-S — the University of Oxford coronavirus vaccine candidate
Sinopharm— China’s state-owned pharmaceutical company — is the first in the world to start Phase III trials
Chinese pharmaceutical, Sinpharm, is the first in the world to start Phase III trials on a potential coronavirus vaccine. The vaccine is being developed in Wuhan — the same place where coronavirus first originated.
The company is working on an “inactivated” vaccine which is produced after scientists are able to grow the virus again in a lab setting and kill it.
ZyCov-D, a potential coronavirus vaccine candidate by Zydus Cadila
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(Representative image)
Drug firm Zydus Cadila on Wednesday said it has started human clinical trials of its COVID-19 vaccine candidate ZyCoV-D.In the phase of trials, the company will be enrolling over 1,000 subjects across multiple clinical study sites in India.
The adaptive phase I/ II human clinical trials of ZyCoV-D have commenced with the first human dosing, it said, adding that the adaptive phase I/II dose-escalation, multi-centric study will assess the safety, tolerability and immunogenicity of the vaccine. The entire trial is expected to be completed in a year.
CoronaVac by Sinovac Biotech might be available by autumn
Chinese pharmaceutical Sinovac Biotech on July 16 got the approval to conduct Phase III clinical trial for its coronavirus vaccine candidate, CoronaVac. The company will now hire 9,000 health professionals who are currently working in a COVID-19 facility in Brazil and will start the clinical trial this month.
It started developing COVID-19 vaccine as early as January 28. It aims to introduce its coronavirus vaccine this year.
COVAXIN, India’s first indigenous COVID-19 vaccine candidate by Bharat Biotech and ICMR
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COVAXIN — developed by the Indian vaccine and biotherapeutics manufacturer Bharat Biotech — is the first COVID-19 vaccine candidate in the country to get DGCI’s (Drug Controller General of India) nod. DGCI has allowed the company to conduct phase I and Phade II clinical trials. ICMR aims to launch the vaccine by August 15.
There are several firms whose coronavirus vaccine are likely to go under human trials soon like Moderna
mRNA-1273, Moderna’s vaccine candidate to begin human trials on July 23
The US-based biotech firm Moderna said on July 14 that it would enter the final stage of human trials for its COVID-19 vaccine on July 27 after the vaccine showed promising results. The Phase 3 trials are likely to have 30,000 volunteers in the US. Half of the participants will be given a 100 mg dose of the vaccine while the other half will receive a placebo. Moderna’s vaccine, if proven successful, could be available by the end of the year or early 2021.
Some of the other institutions whose vaccine candidate which are in the Phase I of the clinical trial include Medicago Inc., Walvax Biotech, Curevac, Imperial College London, University of Queensland, Vaxine Pty Ltd, Clover Biopharmaceuticals, Gamaleya Research Institute, Genexine Consortium and Pfizer.
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Moderna's COVID-19 vaccine will be in final stages of human trial starting July 27