The six-story home sits along the River Seine, right next to the Eiffel Tower and the Champs de Mars, the public green space that surrounds it.
The mansion's location at the intersection of Avenue de Suffren and Quai Branly in the ritzy seventh arrondissement is one of the most sought-after areas of Paris.
The seventh arrondissement is home to embassies and ministry buildings, as well as world-renowned museums and cultural institutions.
According to Paris Property Group, a view of the Eiffel Tower can double or triple a property's price.
"Since the end of 2018, we've noticed increased interest in the 7th linked to Brexit with the return of French citizens from abroad who have a high budget at their disposal," Dominique de Saint Priest of the Era Saint Priest agency told Paris Property Group.
The opulent mansion remains mysterious except to those elite few who may actually be prospective buyers.
The owners of the mansion, reportedly two elderly sisters who are "representatives of a rich French dynasty," have forbidden Kalinka Realty to publish photos of the interior and any additional details about the home, the company told Business Insider.
If the home sells for its asking price of $280 million, it would be one of the most expensive homes ever sold in the world.