Brian Snyder/Reuters
The most recent stream started on Saturday, when Cuban responded to a tweet from Ryan Saavedra, a writer for the alt-right site Breitbart, about a Russian company that purchased a Canadian uranium mining company with a subsidiary in the US in 2013.
Clinton was secretary of state at the time of the Russian acquisition. She was one of nine agency heads who had to sign off on the deal because of its potential effects on national security.
Trump has called for an investigation into the deal. Right-wing media has attempted to connect the deal to donors of the Clinton Foundation, many of whom had an interest in seeing the deal approved. However, there is no evidence anything improper occurred.
Cuban countered with another point.
"Question for you," Cuban tweeted at Saavedra. "Why does it matter that any uranium was sold to the Russians or anyone else for that matter?"
Cuban pointed to the fact that the US Nuclear Regulatory Commission (NRC) prohibits the export of any uranium from the US to a foreign country. So while a Russian company owns the US mines, it is not able to export uranium from the US.
"I would congratulate him because he sold them a useless asset," Cuban tweeted when asked what he would say if Trump, instead of Clinton, had been involved in signing off on the deal. "They can't export any of that uranium. It's worth less than Trump U degree."
Cuban also said he spoke to a Clinton Foundation donor connected to the uranium mine, Frank Giustra, who told Cuban he had nothing to do with the sale.
Cuban's comments, however, drew the ire of a wide array of Twitter followers who believed Clinton to be part of an improper scheme.
Cuban appeared to joke that Trump should sign an executive order to ban the sale of uranium to adversarial nations, which is already illegal.
"Why hasn't @realDonaldTrump reversed the sale of our Uranium mines and stopped all sales of Uranium to Russia/NoKo/china etc?" Cuban said.
"I know right! She screwed us all!" Cuban later tweeted about Clinton. "When is @realDonaldTrump going to issue an exec order banning the export of uranium from those mines!"
Cuban also weighed in on the current state of Trump's presidency and other issues, like net neutrality and healthcare.
"If any republican other than maybe @tedcruz had won the republican nomination, we would be a far more united and safer country," Cuban tweeted.
Cuban also criticized Health and Human Services Secretary Tom Price, Education Secretary Betsy DeVos, EPA administrator Scott Pruitt, and Housing and Urban Development Secretary Ben Carson, tweeting that the cabinet members "have been awful."
On net neutrality, Cuban said the Federal Communication Commission is doing a good job. And on healthcare, he reiterated previous opinions that the insurance system in the US should be drastically altered.
View some of the tweets below:
Why hasn't @realDonaldTrump reversed the sale of our Uranium mines and stopped all sales of Uranium to Russia/NoKo/china etc ? https://t.co/VEqaXVV9ls
- Mark Cuban (@mcuban) August 7, 2017
Then @realDonaldTrump failed to issue the executive order we are asking for ? He decided not to stop the criminal Clinton's dastardly deed? https://t.co/TXnz5jwpQA
- Mark Cuban (@mcuban) August 8, 2017
Will all Americans join us in asking @potus to issue an exec order ending Hillary Clinton's horrific export of our uranium to the Russians? https://t.co/vYnpiyB8jA
- Mark Cuban (@mcuban) August 8, 2017
I also seriously believe @SecPriceMD , @ScottPruittOK, @RealBenCarson and Devos have been awful. https://t.co/c31Yp3qjXi
- Mark Cuban (@mcuban) August 7, 2017