Kevin Winter/Getty Images for Coachella
Leading up to the performance, rumors swirled that Rihanna and Jay Z, both collaborators, were set to join Drake on-stage and surprise the massive crowd.
But it was Madonna who appeared mid-way through the rapper's 75-minute set, right after he sang the song "Madonna" off his newly released "If You're Reading This It's Too Late" album.
The 56-year-old pop star took the stage to perform "Human Nature":
Christopher Polk/Getty Images for Coachella
Christopher Polk/Getty Images for Coachella
Christopher Polk/Getty Images for Coachella
Christopher Polk/Getty Images for Coachella
YouTube/Coachella
But Drake, who seemed genuinely shocked by the kiss, didn't seem to enjoy it:
Christopher Polk/Getty Images for Coachella
Madonna didn't care, concluding by stating: "Bitch, I'm Madonna" and strutting off the stage.
YouTube/Coachella
"Oh sh*t, what the f*ck just happened?" Drake asked the audience after the incident.
The crowd and social media went nuts after the surprise smooch:
Drake's reaction after kissing Madonna ?????? pic.twitter.com/KmoYhQjA6d
- Hip Hop Depot (@HipHop_Depot) April 13, 2015
Wow. Poor old @Drake haha Madonna laid it on you son ????????
- CityOfGold (@ThePrototypesUK) April 13, 2015
Speith wins the Masters. Madonna kisses Drake. Goin' up on a Sunday.
- Michelle Marie (@MichelleMarieTV) April 13, 2015
YOU LAUGHIN BUT MADONNA JUST STOLE 10 YEARS OF DRAKE'S LIFE FORCE
- wavy-haired samurai (@mo0ty) April 13, 2015
Drake is in the 'Land Before Time' set and brought out Madonna... The jokes write themselves #coachella2015
- Sowmya Krishnamurthy (@SowmyaK) April 13, 2015