London to Venice: Venice Simplon-Orient-Express

The Venice Simplon-Orient-Express is one of the most iconic luxury trains in the world. It features Art Deco interiors, plush fabric, crystal glassware, and a champagne bar.

It's best known for its classic route from London to Venice, with a stop in Paris. But you can also opt for a journey from Paris to Istanbul or from Istanbul to Venice. Tickets start at roughly $2,500 per person.