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But there's a reason Segel has neglected his over 2.5 million followers and it's all because of the backlash he received after announcing that sandwiches are better than burritos during a late night eating session.
At the New York screening of his new movie "Sex Tape," Segel told Variety what went down on the fateful night that led him to quit Twitter:
"I realized that's not a power I want to wield. At one point, at 3 a.m., I was deciding between eating a sandwich and a burrito, and I ate a sandwich. It was delicious, and I tweeted, 'Sandwiches are better than burritos.' And then there was a firestorm of debate. People hated me: 'You don't know about burritos,' they'd say. I decided that was too much responsibility for me."
Segel did try to make amends:
Ok. Burrito lovers. I made a giant delicious burrito. Get off my back. It's still not as good as a sandwich. Sorry pic.twitter.com/ZAz54hIL
- Jason Segel (@jasonsegel) November 28, 2011
But alas, the whole thing was "too much responsibility."
Segel appeared on "The Late Show" with David Letterman last night and the two discussed the incident.
Segel, who stands by his sandwich preference, revealed his top five favorites:
- BLT
- Reuben
- Tuna Melt
- Grilled cheese
- PB&J
Letterman agreed that he is a "a big fan of the BLT," but told the actor "what you omitted there is a good club sandwich."
Ultimately, Letterman says, "My all time favorite is wheat bread, ham, lettuce, tomato, mayonnaise, and mustard. And really, really sharp cheddar cheese. That's like a week off, you have one of those babies and you're fine."
Segel, who had to cut down on his sandwich intake to prep for all of the nude scenes in "Sex Tape," says he found a great new weight loss trick.
"I had to lose a bunch of weight for this movie," Segel told Letterman. "So I made a really simple rule at Mexican restaurants: you should only eat the amount of chips they give you in the basket, I don't ask for more - even if there's guacamole left!"
Watch the full interview below: