Of the 546 fresh cases, 458 were reported from the Greater Hyderabad Municipal Corporation (GHMC), followed by Ranga Reddy district, neighbouring Hyderabad, with 50 cases.
A state government bulletin said 3,506 people have been discharged so far, while 3,363 were under treatment.
According to the bulletin, 3,188 samples were tested on Saturday.
Cumulatively, 53,757 samples have been tested.
Meanwhile, BJP MLA Raja Singh on Saturday said his gunman has tested positive for the virus and that he underwent the test whose result is awaited.
In a video message, he expressed confidence that he would defeat the virus even if he tested positive. SJR