'Scream 6' characters ranked from most to least likely to die

Since Neve Campbell isn't returning to play Sidney Prescott in "Scream 6," Courteney Cox's Gale Weathers is the only core cast member from the original trilogy headlining the film. So unfortunately that puts her right on the chopping block in the sequel.

The new trailer shows a scene where Ghostface starts hunting Gale in her apartment and although she can hold her own, even threatening to shoot the killer "in the fucking head," it's not exactly looking good for her.

Ghostface makes a point of saying that they're not like the previous people to don the iconic mask, and what better way of standing apart from the rest than by slaughtering Gale in her own home?

It does feel like cheating to put both Mindy and Chad Meeks-Martin down in the same entry, but it makes sense. Their uncle, Randy Meeks (Jamie Kennedy), died back in "Scream 2" in one of the franchise's most devastating deaths, so could the twins face the same fate?

Unfortunately, it looks highly likely. There's a brief moment where Ghostface attacks Mindy and pins her up against a subway train door, and it would be very surprising if she made it out of that scene without at least some sort of wound.

Mind and Chad both made it out alive of 2022's "Scream" with survivable wounds, and since the "Scream" franchise has always been about escalating the violence and building on the previous film, it's plausible that they'll be quite high on Ghostface's list. Let's hope death doesn't run in the family.

"Spider-Man" and "The Grand Budapest Hotel" star Tony Revolori joins "Scream 6" as Gabe, who's clearly a student in New York along with the rest of the young cast. He only shows up briefly in the footage, but he just screams easy-second-kill for Ghostface.

Tara Carpenter is an interesting potential victim because she survived several Ghostface attacks in the 2022 movie, but the whole story really revolved around her sister, Sam.

So, if Tara were to die in the sequel, it would definitely push Sam's character in an interesting direction because they both rely on each other.

We also have to acknowledge the "Wednesday" in the room. Jenna Ortega has obviously had huge success because of the Netflix series, and it's possible that she'll want to focus on leading her own franchise rather than missing out on filming because of another "Scream" film further down the line.

That's obviously just speculation and it could also go the other way because she's already shown that she enjoys playing these kinds of characters thanks to projects like "X" and "The Babysitter: Killer Queen."

Who knows, maybe she'll be back for a third film? But Tara's death would be a huge surprise for the audience considering how popular Ortega is right now.

"Trainwreck," "Arrow," and "She-Hulk" star Josh Segarra is a newcomer to the franchise, and we don't know much about his character other than his name: David. He can be spotted in the subway scene along with the rest of the key characters, and he's also with Gale and Mindy when Tara suggests they "execute" Ghostface.

The fact that he doesn't have a line of dialogue and doesn't show up in any moments where Ghostface is attacking people is a little suspicious. He could be one of the killers, but he could equally wind up getting brutally murdered, so it's hard to make a prediction on this one.

Another newcomer in the trailer is Dermot Mulroney as Williams, and we don't know much about him either. It's possible that he's a detective, or at least part of law enforcement in some way judging by the gun on his hip.

It's hard to predict his chances, but considering one shot in the trailer shows him bloody and alone, he's definitely going to have a fight on his hands. Basically, let's not get too attached to Williams.

Oh yes, Samara Weaving is making her "Scream" debut in the sixth film!

It's perfect because she collaborated with directors Matt Bettinelli-Olpin and Tyler Gillett on the comedy horror "Ready or Not" back in 2019.

The Australian actor is playing a woman named Sasha in the film, and she makes a blink-and-you'll-miss-it appearance towards the end of the trailer where she's stood in a dingy, deserted alleyway talking to someone on the phone.

It would be silly to kill Weaving off this quickly because she'd be a great ongoing addition to the franchise. Keep her in!

Oh, come on. It would be an actual crime to bring Hayden Panettiere back as Kirby Reed to just kill her off in the same film.

"Scream" fans have spent years begging for Panettiere to come back after her scene-stealing performance in 2011's "Scream 4."

Obviously, it's not impossible that she could get brutally killed as revenge for surviving the fourth film, but it would just feel mean. She survived Jill Roberts and schooled her on a lot of horror trivia, so let Kirby live, even if it's just to criticize "elevated" horror movies and snobbery.

Let's face it, this whole new franchise is focused around the Carpenter family and Sam Carpenter's connection to Billy Loomis (Skeet Ulrich). That arc is clearly continuing through "Scream 6" judging by that moody shot of Sam looking at the old Ghostface mask.

That's not to say she's going to make it out of this unscathed as it looks like she gets thrown off a balcony inside that creepy shrine set at one point, so Sam's definitely going to get put through the wringer.

But chances are she'll live to fight/stab/shoot another day.