18 on-screen friends who are actually best friends in real life

Victoria MontaltiJul 6, 2022, 02:38 IST

Drew Barrymore and Cameron Diaz; Martin Short and Steve Martin.Tommaso Boddi/Getty Images; Bruce Glikas/Getty Images

Hollywood has given us many fictional friendships that have turned into real-life friendships.
Some duos, like the frenemies of "The Office" and "Victorious," might surprise you.

Jane Fonda and Lily Tomlin are life-long friends who have played pals in several projects.

Jane Fonda and Lily Tomlin.Kevin Winter/Getty Images

Steve Martin and Martin Short were always destined to be friends, just going by their matching names.

Martin Short and Steve Martin.Bruce Glikas/Getty Images

Leonardo DiCaprio and Tobey Maguire became friends as child actors, and have since played friends in two films.

Leonardo DiCaprio and Tobey Maguire.Victor Boyko/Getty Images

It's comforting that Rachel Green and Monica Geller's friendship lives on through "Friends" alums Jennifer Aniston and Courteney Cox.

Courteney Cox and Jennifer Aniston.Gregg DeGuire/Getty Images

Matt Damon and Ben Affleck are childhood friends, famously played friends in "Good Will Hunting," and continue to support each other today.

Matt Damon and Ben Affleck.NBC/Getty Images

Michelle Williams and Busy Philipps became inseparable while playing teenage best friends in the early 2000s.

Michelle Williams and Busy Philipps.Frazer Harrison/Getty Images

Drew Barrymore and Cameron Diaz were friends before "Charlie's Angels" and constantly talk today, over 20 years later.

Drew Barrymore and Cameron Diaz.Tommaso Boddi/Getty Images

Brad Pitt and George Clooney have a long history of pranking each other on and off film sets.

Brad Pitt and George Clooney.Jason LaVeris/Getty Images

"One Tree Hill's" Hilarie Burton, Bethany Joy Lenz, and Sophia Bush are still besties and even host an "OTH" podcast together.

Hilarie Burton, Bethany Joy Lenz, and Sophia Bush.CBS Photo Archive/Getty Images

"Scrubs" stars Donald Faison and Zach Braff also share a podcast documenting their on- and off-screen friendship.

Donald Faison and Zach Braff.Paul Archuleta/Getty Images

Salma Hayek was Penélope Cruz's first friend in America. They gave each other the nickname "huevos" while filming together.

Salma Hayek and Penélope Cruz.Kevork Djansezian/Getty Images

"The Sisterhood of the Traveling Pants" cast have an undying bond, and all still celebrate milestones and holidays together.

America Ferrera, Amber Tamblyn, Blake Lively, and Alexis Bledel.Andrew Toth/Getty Images

Jenna Fischer and Angela Kinsey have created a podcast and written a book about their time as real (and fictional) coworkers and friends on "The Office."

Jenna Fischer and Angela Kinsey.NBC/Getty Images

"Pretty Little Liars" stars Ashley Benson and Shay Mitchell bring out each other's goofy sides.

Ashley Benson and Shay Mitchell.Desiree Navarro/Getty Images

Ariana Grande and Elizabeth Gillies have continued their singalongs from their "Victorious" days.

Elizabeth Gillies and Ariana Grande.Alberto E. Rodriguez/Getty Images

Kevin Hart and Dwayne Johnson have one of the most enviable bromances in Hollywood.

Kevin Hart and Dwayne Johnson.Albert L. Ortega/Getty Images

Childhood besties Millie Bobby Brown and Noah Schnapp made a marriage pact.

Noah Schnapp and Millie Bobby Brown.Cindy Ord/Getty Images

Zendaya and Hunter Schafer's vulnerable relationship on "Euphoria" shaped their real-life friendship.

Hunter Schafer and Zendaya.Jeff Kravitz/Getty Images

What the star-studded cast of 'Minions: The Rise of Gru' looks like in real life

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