No. 6: Bromium – Turning computer security on its head

Company: Bromium 

What it does: It's been a long time since a startup with established cofounders came up a really good way to fend off computer viruses. Bromium launched its much-anticipated new computer security product earlier this month. It's tech is like having a thin sheet of glass between each app and the guts of your PC. A virus picked up on the 'net or through e-mail can't get through the glass to harm the actual computer. (Read more: Startup Bromium Could End Computer Viruses Forever)

Why its disruptive: Security has become a multibillion business built on the idea that to defend yourself, you have to disarm each way the bad guys can break in. Bromium lets them break in, and stops them from doing harm after that.

Who gets hurts: Traditional antivirus security companies like Symantec, Trend Micro, McAfee. Enterprises won't ditch their typical security software right away but this should lead to whole new ways to think about security.

Who else wins: Any other security company that's willing to attack the problem with new tech like virtualization.