AP Photo/Jess Tan
The legendary boxer had been suffering from respiratory symptoms which were linked to Parkinson's Disease.
Since he died, prominent artists, politicians, and public figures - from Barack Obama and Donald Trump to Sean Diddy Combs and Hamilton auteur Lin Manuel-Miranda - have paid homage to the boxing great.
Here's what some are saying:
@MuhammadAli A champion. In the ring. In life. #TheGreatest
- Hugh Jackman (@RealHughJackman) June 4, 2016
God came for his champion. So long great one. @MuhammadAli #TheGreatest #RIP pic.twitter.com/jhXyqOuabi
- Mike Tyson (@MikeTyson) June 4, 2016
Ali, you were generous every time I met you. Thank you for all you did for so many. Your memory will live on forever #Olympicgold #GOAT
- Caitlyn Jenner (@Caitlyn_Jenner) June 4, 2016
We love you. We miss you. Rest in peace great one. #RIPALI @RevoltTV pic.twitter.com/q3hBkO5yHp
- Sean Diddy Combs (@iamdiddy) June 4, 2016
Didn't know Muhammad was dead??At T.Hearns/Sugar Ray
Fight in Vegas he explained boxing 2me.I Yelled,He Said Ooo-Wee Cher u got a mouth on u
- Cher (@cher) June 4, 2016
Ran out of room,got caught up in memories.it was so much fun to be in ring with him.Son was like a kid pic.twitter.com/MtJERqpOJ4
- Cher (@cher) June 4, 2016
"I am the greatest!" Yes you were #MuhummadAli!!!! https://t.co/UXG1hYDyxI
- octavia spencer (@octaviaspencer) June 4, 2016
This man inspired me. The Champ. Rest in peace. 2016 is a rough one. pic.twitter.com/GVA6wCenEZ
- Idris Elba (@idriselba) June 4, 2016
Thanks CHAMP!!! RIP! Nuff said.
- Samuel L. Jackson (@SamuelLJackson) June 4, 2016
God bless Muhammad Ali peace and love to all his family. ????????
- #RingoStarr (@ringostarrmusic) June 4, 2016
Ali, the G-O-A-T. A giant, an inspiration, a man of peace, a warrior for the cure. Thank you. pic.twitter.com/MCLyJhLC0X
- Michael J. Fox (@realmikefox) June 4, 2016
He shook up the world, and the world's better for it. Rest in peace, Champ. pic.twitter.com/z1yM3sSLH3
- President Obama (@POTUS) June 4, 2016
Paul on the passing of Muhammad Ali: https://t.co/AfhcmeL4Vq pic.twitter.com/2wuQdrAtJf
- Paul McCartney (@PaulMcCartney) June 4, 2016
Our families would get together, just sit around and watch you fight.
You fought for so much.
Thank you Champ pic.twitter.com/xgA4UOIAcP
- Pharrell Williams (@Pharrell) June 4, 2016
Rest in peace, champ. #thegreatest pic.twitter.com/PAABp2QgwR
- Kris Jenner (@KrisJenner) June 4, 2016
You'll always be The Greatest for more than just what you did in the ring. A champion to so many people in so many ways.
- Tiger Woods (@TigerWoods) June 4, 2016
Goodbye my friend. You were Great in so many ways. https://t.co/4rY68GF8mB
- Bill Clinton (@billclinton) June 4, 2016
Muhammad Ali is dead at 74! A truly great champion and a wonderful guy. He will be missed by all!
- Donald J. Trump (@realDonaldTrump) June 4, 2016
His may be the Greatest of 20th century American stories. Muhammad Ali, rest In peace 1942-2016
- Neil deGrasse Tyson (@neiltyson) June 4, 2016
The world has lost a Legend and real Champion. #RIPMuhammadAli pic.twitter.com/0CHBR7od5N
- Oprah Winfrey (@Oprah) June 4, 2016
You will always be my hero ... #MuhammadAli pic.twitter.com/Rbp7Be3JAK
- Lionel Richie (@LionelRichie) June 4, 2016
I met him a few times . And he was always the funniest guy in the room. So sad. pic.twitter.com/gl6hjV7Y0W
- Chris Rock (@chrisrock) June 4, 2016
...Passionately smashing every expectation.
Every action's an act of creation. #AliBomaye pic.twitter.com/tS80h82zYg
- Lin-Manuel Miranda (@Lin_Manuel) June 4, 2016