Maker Studios creates content aimed mostly at millennials.
Re/code reports Maker receives 5.5 billion views per month on its channels.
Maker is home to one of YouTube's biggest stars, "PewDiePie," a 24-year-old Swedish videogame commenter, Felix Arvid Ulf Kjelberg.
All together, Kjelberg has received 3.7 billion views on YouTube and has 23.9 million subscribers.
The Financial Times valued Maker at $300 million in 2013.
The Mouse House wouldn't be the first studio to invest in YouTube talent.
DreamWorks Animation purchased AwesomenessTV for $33 million last year, a deal that could eventually pay up to $117 million.