Aside from the fact that he tends to support Republican candidates, that's one main reason why he's not going to vote for her.
"I don't need anybody crapping all over what I do for a living," Cooperman, 72, told CNN Money's Cristina Alesci.
He added that Clinton "hangs out with these people in Martha's Vineyard and in the Hamptons and the very first thing she does is criticize hedge funds."
Cooperman said there's one thing that gets to him even more than Clinton.
"I don't need someone coming out and blatantly crapping on hedge funds. Most of the hedge funds I know, whether it is Carl Icahn, Stan Druckenmiller, Michael Steinhardt, Bill Ackman, I apologize to those I'm leaving out, Dan Loeb, these are extraordinary, generous people that work at what they do because they love what they do and are taking their financial success and giving it back to the system. This notion of crapping all over hedge funds is so bogus it makes me nauseous. The only thing that makes me more nauseous is those hedge funds that support her."
During the interview, Cooperman said that he has lived the "American dream."
He grew up poor in the South Bronx. His father was a plumber.
His parents were also immigrants and he was the first of his generation to graduate from college. He attended Hunter College in Manhattan and later graduated with his MBA from Columbia.
When he finished school, he had no money, student loan debt and a six-month old child to take care of.
He ended up going to work for Goldman Sachs where he stayed for 25 years where he became a partner and CEO of Goldman Sachs Asset Management.
After Goldman, he founded hedge fund Omega Advisors.
He now has an estimated networth of $3.7 billion. He has also donated millions to charity and to his alma maters. Cooperman and his wife Toby, a recently-retired teacher who taught special needs children in New Jersey for 25 years, have also signed Warren Buffett and Bill Gates' "Giving Pledge."
Watch the CNN Money video below: