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Between dazzling fireworks and delicious cold brews, millions of people will be firing up their grills and throwing on tenderloins, flank steaks, pork shoulder and many more combinations of savory meats to celebrate.
But what actually happens to the meat when it hits high heat that makes it so mouthwatering?
The video below, from our friends at the American Chemical Society, explains the delicious chemical reactions that transform a bloody chunk of meat into a tasty browned steak.
Before it touches the grill
A common misconception is that the red color of meat comes from blood, but the muscle's ruby red hue actually stems from the animal's behavior. Cows spend a ton of time standing, so their muscles must be able to withstand their weight for long stretches of time without fatiguing.
This creates lots of slow-twitch muscle fibers, which are more efficient at consuming oxygen and transforming it into energy because they contain more of a special protein called myoglobin, which turns red when it's bound to oxygen. The more myoglobin a piece of meat has, the redder it will be.
The same thing happens in the muscles of people who engage in endurance sports, like marathons and long-distance swimming.
Eventually, however, oxygen-exposed meat will turn back to gray - a sign that it's gone bad.
To side-step this, many grocery stores package their meat under carbon monoxide - the carbon monoxide stops the oxygen from reacting with the muscle over time, keeping it red.
Get that charcoal out
To perfect that barbecue flavor, you need some charcoal. While gas is convenient, it totally misses the mark in terms of good barbecue.
Many people don't realize that charcoal is actually wood that's been heated in the absence of oxygen. Wood chips contain a chemical compound called lignin which, when fired up, gets broken down and produces another compound called guaiacol. The guaiacol in the charcoal is what then produces that deep, smokey wood fired flavor.
Fire it up
The heat of the grill also changes that myoglobin - above 140 Fahrenheit, the molecule unfolds to the point where it can't hold onto oxygen and turns a tan color due to a compound called hemichrome. At about 170 Fahrenheit, myoglobin unfolds again into a new structure called metmyoglobin, which looks a darker grayish brown.
But the "holy grail of all culinary chemical reactions," according to the video, is when the Maillard reaction rearranges the amino acids and sugars in the muscle meat to produce the quintessential browned color and mouthwatering taste of barbecue.
This rearrangement occurs at around 285 Fahrenheit giving browned meat its distinctive color and flavor.
Overzealous grillers beware
It may be tempting to go overboard with that char to get more grilly flavor, but searing your meat into oblivion has some pretty nasty consequences. Not only does the meat lose its mouth-watering flavor and texture, but it also produces potentially cancer-causing compounds.
This can all be avoided by cooking your meat at lower temperatures and flipping it often. Insider tip: Invest in a meat thermometer to make sure your meat isn't overdone.
Happy barbecuing!Watch the full video, from the American Chemical Society's Reactions channel, on YouTube: