The actor showed up on the late-night host's set in a tank with two "goddesses."
It was Sheen's first time on the Warner Bros. lot in two years since his firing from "Two and a Half Men."
During his interview, Sheen made reference to his notorious 2011 meltdown — which he now calls a melt forward — blaming it on a combination of Dave Chappelle and testosterone cream.
The "Scary Movie 5" actor claims he suffered a ruptured hernia from laughing too hard while watching the popular "Chappelle Show" sketch about a blind white supremacist.
Sheen claimed the producers of "Two and a Half Men" thought he overdosed, and, as a result, fired him from the CBS show.
As for the testosterone cream, Sheen said he was using it in excess.
Here's Sheen's big entrance on "Conan":
And, here he is discussing the cause of his "melt-forward":