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The poll, from Quinnipiac University, found Clinton leading Sanders among national Democratic-primary voters, 44% to 42%.
That was a wild swing from a mid-December Quinnipiac poll that found Clinton leading 61% to 30% nationally over Sanders.
"Democrats nationwide are feeling the Bern as Sen. Bernie Sanders closes a 31-point gap to tie Secretary Hillary Clinton," said Tim Malloy, the assistant director of the Quinnipiac poll.
The Quinnipiac survey is the most bullish for Sanders on a national scale recently. Clinton remained ahead of Sanders in a Real Clear
Still, the Friday survey presented fresh signs of momentum for Sanders, who surprised much of the political world when he came close to overtaking Clinton in the Monday-night Iowa caucuses. He also appears primed for a win in New Hampshire, which holds its primaries next Tuesday: He's up by more than 20 points in an average of recent polls.
The Quinnipiac poll found that Sanders would fare better than Clinton in hypothetical general-election matchups, an argument he has started to make on the campaign trail. For example, while Clinton would lose to Sen. Marco Rubio (R-Florida) by seven points, Sanders would tie him, according to the survey. He would also double Clinton's margin of victory over real-estate magnate Donald Trump.
For his part, Trump continued to lead on the Republican side, according to Quinnipiac. He received 31% of the vote, followed by Sen. Ted Cruz (R-Texas) at 22% and Rubio at 19%.