This marks the first time the US Navy has had a carrier in the region since US guided-missile destroyers struck Syrian President Bashar Assad's air force after his regime carried out a deadly chemical weapon attack on civilians.
In the immediate aftermath of that strike on April 6, Russia, Assad's stalwart ally, sent two corvettes of their own.
The US has dispatched the Bush and four guided-missile destroyers as part of a carrier strike group.
The carrier arrives at a time when US and coalition forces have all but stomped out the last remaining ISIS strongholds in Iraq and Syria, though they increasingly find themselves under attack from new adversaries - Iranian-backed pro-Assad forces.
Iran recently released footage of one of its drones scoping out a US drone, and the very next day the US announced an F/A-18 had shot down a pro-Syrian drone.
Increasingly, US-led coalition forces find themselves bombing pro-Syrian and Iranian-backed forces that threaten US troops in deconfliction zones.
With the addition of the aircraft carrier, the US will have an additional few dozen F/A-18s handy to police the skies.