Four-time Super Bowl champion Mike Webster retired from the NFL in 1990.
After his retirement, he had amnesia, dementia, depression, and acute bone and muscle pain. He also became very agitated and restless.
In 2002, Webster died of a heart attack at the age of 50.
The autopsy revealed that Webster had CTE, making him the first former NFL player to be diagnosed with the neurodegenerative disease. His autopsy is credited with initiated changes in football regarding head injuries and player safety.
Webster's doctors said that multiple concussions caused damage to his frontal lobe, resulting in cognitive dysfunction.