Sultan Qaboos bin Said al Said, 75, became ruler of Oman when he launched a successful coup against his father in 1970.
Since taking the throne, Qaboos has pursued reforms in the small sultanate, according to AFP.
Oman sits across the Strait of Hormuz from Iran, and the sultan helped arrange secret US-Iran meetings that started in Muscat in 2012. Those meetings led to the first formal talks between the US and Iran since the 1979 Islamic Revolution, helping to pave the way for the 2015 nuclear deal.
In return for facilitating those meetings, however, the US reportedly overlooked Oman's worsening record on forced labor and human trafficking.
Qaboos' health has been failing in recent years, and since 2014 he has been hospitalized in Germany on several occasions. He has no designated heir.