The Iskander is "an extremely flexible battlefield system," according to CSIS, and has been deployed to Kaliningrad, where it can reach Poland, Sweden, and the Baltics.
However, it's not invincible to the US' Patriot PAC-3 missiles, according to Popular Mechanics.
You can read more about the Patriot system here >>
Russia has sold the Iskander to Armenia, Algeria and possibly Iran and Syria, CSIS reported. Russia also deployed the Iskander to its Latakia base in Syria in early January 2017.