THEN: Matthew Fox was the leader of the Oceanic 815 survivors, Jack Shephard.
NOW: Fox has tried to become a breakout movie star, first in 2008's "Vantage Point" and as a villain in flop "Alex Cross."
THEN: Evangeline Lilly played fugitive bad girl Kate Austin.
NOW: Lilly played elf Tauriel in "The Hobbit: The Desolation of Smaug." She's also been in Oscar-winning "The Hurt Locker" and "Real Steel."
next slide will load in 15 secondsSkip AdSkip AdTHEN: Josh Holloway played con man Sawyer (James Ford), who gave dished out nicknames from Freckles to Blondie.
NOW: Halloway currently stars on CBS show "Intelligence."
He's also been in a string of movies including "Mission: Impossible — Ghost Protocol" and bomb "Paranoia."
Later this month he'll star opposite Arnold Schwarzenegger in crime drama "Sabotage."
THEN: Elizabeth Mitchell played doctor Juliet Burke and Sawyer's love interest.
NOW: Mitchell has jumped from ABC's cancelled "V" to NBC's new hit "Revolution."
THEN: Michael Emerson played main bad guy Benjamin Linus.
next slide will load in 15 secondsSkip AdSkip AdNow: Emerson has found a home on CBS' show "Person of Interest."
Emerson also took over voicing duties for the animated version of the Joker in "Batman: The Dark Knight Returns."
THEN: Tania Raymonde played Ben's daughter Alex Rousseau.
NOW: Raymonde has most recently appeared as a vet on CBS' "The Big Bang Theory."
She has also appeared on "Hawaii Five-0," the "90210" reboot, and "Chicago Fire."
Last year, Raymonde starred in horror thriller "Texas Chainsaw 3D."
THEN: Jorge Garcia played Hugo "Hurley" Reyes who found himself extremely unlucky after winning the lottery with what came to be known as the ever ubiquitous numbers: 4, 8, 15, 16, 23, 42.
NOW: Garcia recently made an appearance on ABC's "Once Upon a Time" series as a Giant.
He has also starred on episodes of "How I Met Your Mother," "Hawaii Five-0," "Fringe," and the dropped "Mr. Sunshine," before appearing on his own cancelled series, "Alcatraz."
This year, he played Steve Wozniak in a parody of "jOBS" called "iSteve."
next slide will load in 15 secondsSkip AdSkip AdTHEN: Emilie De Ravin starred as Claire Littleton, the girl who gave birth on the island before disappearing in season 4 and turning into a crazed squirrel-loving wild child.
NOW: De Ravin dyed her blonde locks brown to play Belle on ABC's "Once Upon a Time."
THEN: Dominic Monaghan played druggie lead singer Charlie Pace of fictional band "Drive Shaft."
NOW: He now hosts a reality BBC America program "Wild Things with Dominic Monaghan" in which he travels to exotic locations.
Monaghan has also been in several low-budget, low-grossing films along with Crackle's web series "The Unknown."
He has two films out this year, "Deep Burial" and "Molly Moon: The Incredible Hypnotist."
THEN: Terry O'Quinn played wheel-chair bound John Locke who found he could mysteriously walk after crashing onto the island.
next slide will load in 15 secondsSkip AdSkip AdNOW: O'Quinn will lead a Gang Task Force in Fox's new show, "Gang Related."
Previously, the actor returned to ABC for a short time on cancelled "666 Park Ave."
O'Quinn made regular appearances with former co-star Daniel Dae Kim on "Hawaii Five-0" and guest-starred in three episodes of TNT's "Falling Skies."
THEN: Naveen Andrews played Iraqi communications officer Sayid Jarrah.
NOW: Andrews also joined the "Once Upon a Time" crew. He plays Jafar in the show's spinoff series, "Once Upon a Time in Wonderland."
Last year, he played Princess Diana's rumored lover Dr. Hasnat Khan in biopic "Diana" opposite Naomi Watts.
THEN: Maggie Grace played spoiled brat Shannon whose character was compared to Paris Hillton during the casting process.
NOW: Grace went on to become the girl who was kidnapped in "Taken" and then seen again in "Taken 2."
Grace also stars on "Californication," web series "Susanna" and was in two of the "Twilight" films.
next slide will load in 15 secondsSkip AdSkip AdTHEN: Ian Somerhalder played Boone for one season on the island.
NOW: He plays a devilish vampire on CW's "Vampire Diaries."
THEN: Nestor Carbonell played the man who never aged, Richard Alpert.
NOW: Carbonell is playing a sheriff on A&E's "Bates Motel."
Carbonell made appearances in 2008's "The Dark Knight" and "The Dark Knight Rises" as Mayor Anthony Garcia.
He has also appeared on "Psych" and CW's "Ringer."
THEN: Michelle Rodriguez played fiery Ana Lucia.
next slide will load in 15 secondsSkip AdSkip AdNOW: After serving time in jail in 2005 and 2007 for DUI and violating probation respectively, she has returned to the big screen in "Fast & Furious 6."
She will be back in next year's "Fast and Furious 7."
THEN: Daniel Dae Kim played Korean-speaking Jin-Soo Kwon.
NOW: Kim is the star of CBS' "Hawaii Five-0" remake.
THEN: Yunjin Kim played Jin's wife, Sun.
NOW: She stars on ABC series "Mistresses."
Kim also starred in three South Korean films with the latest called "The Neighbors."
next slide will load in 15 secondsSkip AdSkip AdTHEN: Henry Ian Cusick played time-traveling Desmond.
NOW: Cusick appeared on season one of ABC's hit series "Scandal."
He also starred in episodes of "Fringe," "The Mentalist," and "Body of Proof."
Next, he'll be starring on The CW's futuristic show "The 100."
THEN: Sonya Walger played Desmond's love interest Penny.
NOW: Walger was on short-lived ABC drama "FlashForward" and has joined NBC's "Parenthood" in a recurring role.
The actress was also on the cancelled USA show "Common Law."
THEN: Alan Dale played Penny's villainous father Charles Widmore who was obsessed with the magical powers of the island.
next slide will load in 15 secondsSkip AdSkip AdNOW: The actor has shown up on many shows including "NCIS," "Hot in Cleveland," and "Once Upon a Time."
Dale has also appeared in "The Girl with the Dragon Tattoo," "Person of Interest," and will appear in "Captain America: The Winter Soldier."
As for some of the other cast members ...
Adewale Akinnuoye-Agbaje (Mr. Eko) was in "Thor: The Dark World," and box-office bomb "Pompeii." Later this year, he'll be in the remake of "Annie."
Cynthia Watros (Elizabeth "Libby" Smith) had a recurring role on "House, M.D.," and guest appearances on "Grey's Anatomy," and "Hawaii Five-0."
Harold Perrineau (Michael Dawson) was in the film "Zero Dark Thirty," and appeared on FX's "Sons of Anarchy." He'll be on TV series "Growing Up Fisher" and will reunite with fellow Lostie Josh Holloway later this month in "Sabotage."
L. Scott Caldwell (Rose Nadler) has been on "The Secret Life of the American Teenager," "Southland," and AMC's axed series "Low Winter Sun."
Sam Anderson (Bernard Nadler) has made appearances on various shows including "Hawaii Five-0," "Justified," and "Dallas."
Jeff Fahey (pilot Frank Lapidus) has popped up on "Revolution" and CBS' new series "Under the Dome."
Titus Welliver (The Man in Black) was most recently in "Argo," "Man on a Ledge," and "Promised Land." This year, he'll be in "Transformers: Age of Extinction."
Mark Pellegrino (Jacob) has been on "Being Human," "Supernatural," "Revolution," and appeared on an episode of "Person of Interest."
Now, that you know what happened to the castaways on "Lost" ...