Until now, SpaceX has not launched a used Falcon 9 booster more than twice. The reason: the 16-story boosters careen back to Earth from the edge of space at speeds of thousands of miles per hour, which heats and wears down their parts. The booster has to be thoroughly inspected, and parts often need to get refurbished or replaced because of damage.
To make the boosters hold up better, Block 5 will use thermal-protection coating instead of paint. Its engineers also added shielding to the tail-end of the rocket to better protect the heavy, expensive engines. And the booster's grid fins, which guide it to a landing like a skydiver's arms and legs, are made of titanium (which doesn't melt during reentry) instead of aluminum (which gets damaged).
Musk said in March 2017 that each Block 5 booster will fly a minimum of 10 times without replacing major components, though possibly more than that with some refurbishment
"In other words, the only thing you change is you reload the propellant," he said. "With moderate refurbishment that doesn't have a significant effect on the cost, it can be reflown at least 100 times."