Nike's first "Just Do It" spot in 1988 addressed ageism when it featured 80-year-old Bay Area icon Walter Stack, who ran approximately 62,000 miles in his lifetime.
A year later, the company advocated for people with disabilities in a spot starring Paralympian Craig Blanchette.
In 1993, an ad starring Charles Barkley sparked a conversation about whether celebrities and professional athletes should be held to higher standards. "I'm not paid to be a role model. I'm paid to wreak havoc on the basketball court," Barkley says in the ad.
Nike made a statement when a 1995 "Just Do It" ad featured openly gay, HIV-positive runner Ric Munoz. AIDS activists applauded Nike for the campaign.
next slide will load in 15 secondsSkip AdSkip AdIn 1995, Nike tackled gender issues with its "If You Let Me Play" ad, which addressed the benefits of organized sports for girls. The ad featured young girls quoting statistics about the benefits of how sports can improve their lives.
In 2007, Nike featured Matt Scott of the National Wheelchair Basketball Association in a "Just Do It" ad.
Nike touched on gender issues again in 2012 with its "Voices" ad, which celebrated the 40th anniversary of Title IX.
Nike's 2017 "Equality" campaign featured black athletes like LeBron James, Serena Williams, Gabby Douglas, and Kevin Durant, along with actor Michael B. Jordan talking of the parallels between equality in sports and equality in the broader world.
Nike also released the "What Will They Say About You?" ad in 2017, which featured five Middle Eastern women pushing social norms to succeed in sports like boxing and skateboarding.
next slide will load in 15 secondsSkip AdSkip AdEarlier this year, Nike celebrated 30 years of the "Just Do It" tagline with an ad campaign following Serena Williams' path to the US Open.
The Colin Kaepernick ad is the most recent Nike ad to tackle a social issue. The ad comes after Kaepernick brought a lawsuit accusing NFL owners of colluding to keep him out of the league after his protests against racial inequality and police brutality.