Jeff Saturday was a 295-pound center who spent most of his career with the Colts and retired after the 2012 season.
Here is Jeff Saturday at a recent Colts game
Nate Newton, a 320-pound offensive lineman, played most of his 14-year career with the Cowboys before retiring in 1999
Nate Newton is now a shell of his former self
next slide will load in 15 secondsSkip AdSkip AdJaMarcus Russell struggled with his weight with the Raiders and even more before attempting to get back into the NFL.
Earlier this year, JaMarcus Russell lost of ton of weight hoping for another shot in the NFL.
Tom Nalen was a 290-pound center for the Denver Broncos, last playing in 2007.
A skinnier Tom Nalen was recently inducted into the Broncos's Ring of Fame.
Brad Culpepper (no. 77) was a 275-pound defensive tackle for three different teams and retired after the 2000 season.
next slide will load in 15 secondsSkip AdSkip AdHere is Brad Culpepper with his wife on the show "Survivor."
Antone Davis (no. 78) was a 330-pound offensive lineman and grew to 475 pounds after he stopped playing in 1997.
Antone Davis was recently a runner-up on NBC's "The Biggest Loser," where he lost more than 200 pounds.
Matt Birk was a 310-pound center for the Vikings and Ravens who retired last season.
Since he stopped playing, Matt Birk has lost 75 pounds and is now a model.
next slide will load in 15 secondsSkip AdSkip AdAlan Faneca was a 320-pound offensive lineman for the Steelers, Jets, and Cardinals and last played in 2010.
Alan Faneca has lost 100 pounds since he stopped playing.
Mark Schlereth was a 290-pound offensive lineman for Washington and Denver and last played in 2000.
Mark Schlereth is now a slimmed-down commentator on ESPN.
David Pollack was a 260-pound linebacker for the Bengals, last playing in 2006.
next slide will load in 15 secondsSkip AdSkip AdDavid Pollack has lost a lot of weight and is now a college football commentator for ESPN.
Before And After Photos Of NFL Players Who Lost A Shocking Amount Of Weight When They Retired