Two passengers and three flight attendants aboard the Boeing 767 were transported to a local hospital.
The flight was carrying 192 passengers and 11 crew members.
One of the flight attendants remains in the hospital for observation, though all others have been released, a spokesperson for the airline said.
"We are taking care of our passengers and crew." The spokesperson said. "A replacement aircraft, along with additional American employees, arrived in Newfoundland. The aircraft will depart for Milan later today."
The fasten seatbelt light was illuminated at the time.