Salma Hayek is married to Francois-Henri Pinault, the billionaire who runs Gucci, among other brands.
Why she's awesome: Hayek received an Oscar nomination for her role in the film "Frida," and has starred in a number of blockbusters.
She does philanthropy through UNICEF, helping raise awareness for child vaccines. She's also advocated for charitable causes from domestic violence to climate change.
Amal Alamuddin recently married actor and activist George Clooney.
Why she's awesome: Alamuddin is a highly accomplished human rights lawyer who has represented everyone from former Ukrainian Prime Minister Yulia Tymoshenko to the country of Armenia in its fight for recognition of the Armenian Genocide.
Stephanie Seymour is married to billionaire Peter Brant. They reconciled after a rough patch a couple years ago.
Why she's awesome: Seymour is a former supermodel who has appeared on the cover of Vogue and in many Sports Illustrated swimsuit issues.
She's also appeared on television and movies.
Nita Ambani is married to industrialist Mukesh Ambani, the richest man in India.
Why she's awesome: Nita is co-owner of the Mumbai Indians cricket team and is actively involved in fundraising for the blind, education and disaster relief.
She's also the founder of the Dhirubhai Ambani International School, a competitive private school in Mumbai, and a director on the board of Reliance Industries, her husband's company.
Sonia Tudor Jones is married to legendary hedge funder Paul Tudor Jones.
Why she's awesome: Sonia (Klein) is a former Australian fashion model. She's also a big yogi and has been practicing yoga for more than a decade. She's a teacher-certified Ashtanga practitioner and the founder of JOIS Yoga studios, which teaches Ashtanga.
Dasha Zhukova is married to billionaire Russian oligarch Roman Abramovich, one of the richest men in the world.
Why she's awesome: The gorgeous Dasha is an entrepreneur, magazine editor and fashion designer. She's currently working with architect Rem Koolhaas to build a modern art museum in Moscow.
Zhukova and Abramovich have two children.
Mackenzie Bezos is married to Jeff, the billionaire founder of Amazon.
Why she's awesome: Mackenzie is a best-selling novelist who won the National Book Award for "The Testing of Luther Albright."
She has a degree from Princeton, and she and Jeff are well-known philanthropists.
Julie Chen is married to Les Moonves, president and CEO of CBS.
Why she's awesome: Chen is the longtime host of CBS hit "Big Brother," and a co-host on CBS' daytime show "The Talk."
Irina Viner has been married to Russian oligarch and billionaire Alisher Usmanov for more than 20 years.
Why she's awesome: Irina is the head coach for the Russian national gymnastics team, and considered to be one of the most successful gymnastics coaches of all time.
She's also known for her fashion sense and taste in art.
Diane von Furstenberg is married to IAC chairman Barry Diller.
Why she's awesome: Von Furstenberg is a massively successful businesswoman and fashion designer credited with designing the wrap dress.
The pair are major philanthropists in New York City — their latest project is a $130 million floating park to be built in the Hudson River.
Dr. Priscilla Chan is married to Facebook founder Mark Zuckerberg.
Why she's awesome: Priscilla is currently in pediatric residency at the University of California at San Francisco. Despite being married to one of the world's richest men, she had a low-key wedding with Zuckerberg and picked out an off-the-rack dress.
The pair have become major philanthropists, donating to causes ranging from health to education.
Susan Dell is married to computer magnate Michael Dell and the couple has four children.
Why she's awesome: Susan is an elite-level athlete who has competed in the Ironman triathlons. She's also the chairwoman of the fashion label Phi, which has appeared in Vogue.
Gabrielle de Heinrich Sacconaghi is married to billionaire hedge funder Louis Bacon Moore.
Why she's awesome: Sacconaghi is a native of Canada who works as a consultant for art buyers. She graduated from McGill University and she received her master’s in international relations from Cambridge, according to the New York Times.
Ali Pincus is married to Zynga founder Mark Pincus.
Why she's awesome: Ali Pincus co-founded online home furnishings retailer One King's Lane in 2009. It raised $112 million last year, valuing the company at nearly $1 billion.
Lucy Southworth is married to Google co-founder Larry Page.
Why she's awesome: In addition to her model-worthy looks, Southworth did doctoral work at Stanford and is now a research scientist. She's done medical work in South Africa and has also studied at Oxford and the University of Pennsylvania.
The couple have two children.