Youtube screencap / AP Matt Sayles
This was the case for Jeremy Renner, who didn't get his big break until "The Hurt Locker" in 2008 when he was 37 years old.
He went on to become Hawkeye in 2012's $1.5 billion hit "The Avengers" and is now a household name.
Yet, Renner isn't the only late-bloomer when it comes to fame and success in Hollywood.