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That's according to the 2017 Kauffman Index of Growth Entrepreneurship, a study that measures startup growth at the city, state, and national level.
The study focuses on metrics like the average employment growth at startups, how many companies have scaled up, and how many high-growth startups are in a given area. This year, entrepreneurship grew in 26 of the 40 metro areas measured.
The usual big players like San Francisco and Boston stayed relatively stable compared to 2016's ranking, but other mid-sized cities went through some changes in the past year: Indianapolis and Atlanta both jumped 10 spots since last year, and Minneapolis cracked the top 10.
Here are the 21 cities with the highest startup growth: